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L01E Protein kinase inhibitors, antineoplastic and immunomodulating agents

ATC group of level 3 – pharmacological subgroup · in plain English: targeted cancer medicines (kinase inhibitors)

This site has the patient leaflet or the SPC of 353 medicines in this group and its subgroups.

Place in the ATC classification

  1. L Antineoplastic and immunomodulating agents 1,791 medicines
    1. L01 Antineoplastic agents 1,025 medicines
      1. L01E Protein kinase inhibitors, antineoplastic and immunomodulating agents 353 medicines
        1. L01EA BCR-ABL tyrosine kinase inhibitors 101 medicines
        2. L01EB Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors 40 medicines
        3. L01EC B-Raf serine-threonine kinase (BRAF) inhibitors 6 medicines
        4. L01ED Anaplastic lymphoma kinase (ALK) inhibitors 14 medicines
        5. L01EE Mitogen-activated protein kinase (MEK) inhibitors 10 medicines
        6. L01EF Cyclin-dependent kinase (CDK) inhibitors 13 medicines
        7. L01EG Mammalian target of rapamycin (mTOR) kinase inhibitors 27 medicines
        8. L01EH Human epidermal growth factor receptor 2 (HER2) tyrosine kinase inhibitors 4 medicines
        9. L01EJ Janus-associated kinase (JAK) inhibitors 18 medicines
        10. L01EK Vascular endothelial growth factor receptor (VEGFR) tyrosine kinase inhibitors 12 medicines
        11. L01EL Bruton's tyrosine kinase (BTK) inhibitors 8 medicines
        12. L01EM Phosphatidylinositol-3-kinase (Pi3K) inhibitors 6 medicines
        13. L01EX Other protein kinase inhibitors 94 medicines

Active substances in the group

Medicines in the group and its subgroups

MedicineLegal category
Afinitor 10 mg tablets SPC (L01EG02 everolimus) Prescription only (POM)
Afinitor 2.5 mg tablets SPC (L01EG02 everolimus) Prescription only (POM)
Afinitor 5 mg tablets SPC (L01EG02 everolimus) Prescription only (POM)
Alecensa 150 mg hard capsules SPC (L01ED03 alectinib) Prescription only (POM)
Alunbrig 180 mg film-coated tablets SPC (L01ED04 brigatinib) Prescription only (POM)
Alunbrig 30 mg film-coated tablets SPC (L01ED04 brigatinib) Prescription only (POM)
Alunbrig 90 mg film-coated tablets SPC (L01ED04 brigatinib) Prescription only (POM)
Alunbrig treatment Initiation Pack (90 mg film-coated tablets + 180 mg film-coated tablets) (L01ED04 brigatinib) Prescription only (POM)
Axitinib 1 mg film-coated tablets SPC (L01EK01 axitinib) Prescription only (POM)
Axitinib 3 mg film-coated tablets SPC (L01EK01 axitinib) Prescription only (POM)
Axitinib 5 mg film-coated tablets SPC (L01EK01 axitinib) Prescription only (POM)
Axitinib 7 mg film-coated tablets SPC (L01EK01 axitinib) Prescription only (POM)
Ayvakyt 100 mg film-coated tablets SPC (L01EX18 avapritinib) Prescription only (POM)
Ayvakyt 200 mg film-coated tablets SPC (L01EX18 avapritinib) Prescription only (POM)
Ayvakyt 25 mg film-coated tablets SPC (L01EX18 avapritinib) Prescription only (POM)
Ayvakyt 300 mg film-coated tablets SPC (L01EX18 avapritinib) Prescription only (POM)
Ayvakyt 50 mg film-coated tablets (L01EX18 avapritinib) Prescription only (POM)
Bosulif 100 mg film coated tablets (L01EA04 bosutinib) Prescription only (POM)
Bosulif 100 mg hard capsules SPC (L01EA04 bosutinib) Prescription only (POM)
Bosulif 400 mg film-coated tablets SPC (L01EA04 bosutinib) Prescription only (POM)
Bosulif 50 mg hard capsules SPC (L01EA04 bosutinib) Prescription only (POM)
Bosulif 500 mg film coated tablets (L01EA04 bosutinib) Prescription only (POM)
Bosutinib 100 mg film coated tablets SPC (L01EA04 bosutinib) Prescription only (POM)
Bosutinib 400 mg film-coated tablets (L01EA04 bosutinib) Prescription only (POM)
Bosutinib 500 mg film-coated tablets (L01EA04 bosutinib) Prescription only (POM)
Bosutinib Sandoz 100 mg film coated tablet (L01EA04 bosutinib) Prescription only (POM)
Bosutinib Sandoz 400 mg film coated tablet (L01EA04 bosutinib) Prescription only (POM)
Bosutinib Sandoz 500 mg film coated tablet (L01EA04 bosutinib) Prescription only (POM)
Braftovi 50 mg hard capsules SPC (L01EC03 encorafenib) Prescription only (POM)
Braftovi 75 mg hard capsules SPC (L01EC03 encorafenib) Prescription only (POM)
Brukinsa 160 mg film-coated tablets (L01EL03 zanubrutinib) Prescription only (POM)
Brukinsa 80 mg hard capsules SPC (L01EL03 zanubrutinib) Prescription only (POM)
Cabometyx 20 mg film-coated tablets SPC (L01EX07 cabozantinib) Prescription only (POM)
Cabometyx 40 mg film-coated tablets (L01EX07 cabozantinib) Prescription only (POM)
Cabometyx 60 mg film-coated tablets SPC (L01EX07 cabozantinib) Prescription only (POM)
Cabozantinib 20 mg film-coated tablets (L01EX07 cabozantinib) Prescription only (POM)
Cabozantinib 40 mg film-coated tablets (L01EX07 cabozantinib) Prescription only (POM)
Cabozantinib 60 mg film-coated tablets (L01EX07 cabozantinib) Prescription only (POM)
Cabozantinib Ipsen 40 mg film-coated tablets (L01EX07 cabozantinib) Prescription only (POM)
Calquence 100 mg film-coated tablets (L01EL02 acalabrutinib) Prescription only (POM)
Caprelsa 100 mg film coated tablets SPC (L01EX04 vandetanib) Prescription only (POM)
Caprelsa 300 mg film coated tablets SPC (L01EX04 vandetanib) Prescription only (POM)
Cometriq 20 mg hard capsules SPC (L01EX07 cabozantinib) Prescription only (POM)
Copiktra 15 mg hard capsules (L01EM04 duvelisib) –
Cotellic 20 mg film-coated tablets SPC (L01EE02 cobimetinib) Prescription only (POM)
Dasatinib 100 mg film-coated tablets SPC (L01EA02 dasatinib) Prescription only (POM)
Dasatinib 140 mg film-coated tablets SPC (L01EA02 dasatinib) Prescription only (POM)
Dasatinib 20 mg film-coated tablets SPC (L01EA02 dasatinib) Prescription only (POM)
Dasatinib 50 mg film-coated tablets SPC (L01EA02 dasatinib) Prescription only (POM)
Dasatinib 70 mg film-coated tablets not available (L01EA02 dasatinib) –
Dasatinib 80 mg film-coated tablets SPC (L01EA02 dasatinib) Prescription only (POM)
Dasatinib Accord 140 mg film-coated tablets (L01EA02 dasatinib) Prescription only (POM)
Dasatinib Accord 50 mg film-coated tablets (L01EA02 dasatinib) Prescription only (POM)
Dasatinib Accord 70 mg film-coated tablets not available (L01EA02 dasatinib) –
Dasatinib Accord 80 mg film-coated tablets (L01EA02 dasatinib) Prescription only (POM)
Dasatinib Sandoz 100 mg film-coated tablets SPC (L01EA02 dasatinib) Prescription only (POM)
Dasatinib Sandoz 140 mg film-coated tablets SPC (L01EA02 dasatinib) Prescription only (POM)
Dasatinib Sandoz 20 mg film-coated tablets SPC (L01EA02 dasatinib) Prescription only (POM)
Dasatinib Sandoz 50 mg film-coated tablets SPC (L01EA02 dasatinib) Prescription only (POM)
Dasatinib Sandoz 70 mg film-coated tablets SPC not available (L01EA02 dasatinib) –
Dasatinib Sandoz 80 mg film-coated tablets SPC (L01EA02 dasatinib) Prescription only (POM)
Dasatinib Stada 100 mg film-coated tablets SPC no longer supplied (L01EA02 dasatinib) –
Dasatinib Stada 140 mg film-coated tablets SPC no longer supplied (L01EA02 dasatinib) –
Dasatinib Stada 20 mg film-coated tablets SPC (L01EA02 dasatinib) Prescription only (POM)
Dasatinib Stada 50 mg film-coated tablets SPC no longer supplied (L01EA02 dasatinib) –
Dasatinib Stada 80 mg film-coated tablets SPC no longer supplied (L01EA02 dasatinib) –
Dasatinib Teva 100 mg film-coated tablets SPC (L01EA02 dasatinib) Prescription only (POM)
Dasatinib Teva 20 mg film-coated tablets SPC (L01EA02 dasatinib) Prescription only (POM)
Dasatinib Teva 50 mg film-coated tablets SPC (L01EA02 dasatinib) Prescription only (POM)
Dasatinib Teva 70 mg film-coated tablets SPC not available (L01EA02 dasatinib) –
Dasatinib Teva 80 mg film-coated tablets SPC (L01EA02 dasatinib) Prescription only (POM)
Dasatinib Tiefenbacher 100 mg film-coated tablets SPC (L01EA02 dasatinib) Prescription only (POM)
Dasatinib Tiefenbacher 140 mg film-coated tablets SPC (L01EA02 dasatinib) Prescription only (POM)
Dasatinib Tiefenbacher 50 mg film-coated tablets SPC (L01EA02 dasatinib) Prescription only (POM)
Dasatinib Tiefenbacher 70 mg film-coated tablets SPC not available (L01EA02 dasatinib) –
Dasatinib Tiefenbacher 80 mg film-coated tablets SPC (L01EA02 dasatinib) Prescription only (POM)
Dasatinib Tillomed 100 mg film-coated tablets SPC (L01EA02 dasatinib) Prescription only (POM)
Dasatinib Tillomed 140 mg film-coated tablets SPC (L01EA02 dasatinib) Prescription only (POM)
Dasatinib Tillomed 20 mg film-coated tablets SPC (L01EA02 dasatinib) Prescription only (POM)
Dasatinib Tillomed 50 mg film-coated tablets SPC (L01EA02 dasatinib) Prescription only (POM)
Dasatinib Tillomed 70 mg film-coated tablets SPC not available (L01EA02 dasatinib) –
Dasatinib Tillomed 80 mg film-coated tablets SPC (L01EA02 dasatinib) Prescription only (POM)
Dasatinib Zentiva 100 mg film-coated tablets (L01EA02 dasatinib) Prescription only (POM)
Dasatinib Zentiva 140 mg film-coated tablets SPC no longer supplied (L01EA02 dasatinib) –
Dasatinib Zentiva 20 mg film-coated tablets (L01EA02 dasatinib) Prescription only (POM)
Dasatinib Zentiva 50 mg film-coated tablets SPC no longer supplied (L01EA02 dasatinib) –
Dasatinib Zentiva 70 mg film-coated tablets not available (L01EA02 dasatinib) –
Dasatinib Zentiva 80 mg film-coated tablets SPC (L01EA02 dasatinib) Prescription only (POM)
Erlotinib 100 mg film-coated tablets SPC (L01EB02 erlotinib) Prescription only (POM)
Erlotinib 150 mg film-coated tablets SPC (L01EB02 erlotinib) Prescription only (POM)
Erlotinib 25 mg film-coated tablets SPC (L01EB02 erlotinib) Prescription only (POM)
Erlotinib Amarox 100 mg film-coated tablets SPC (L01EB02 erlotinib) Prescription only (POM)
Erlotinib Amarox 150 mg film-coated tablets SPC (L01EB02 erlotinib) Prescription only (POM)
Erlotinib Amarox 25 mg film-coated tablets SPC (L01EB02 erlotinib) Prescription only (POM)
Erlotinib Glenmark 100 mg film-coated tablets SPC (L01EB02 erlotinib) Prescription only (POM)
Erlotinib Glenmark 150 mg film-coated tablets SPC (L01EB02 erlotinib) Prescription only (POM)
Erlotinib Glenmark 25 mg film-coated tablets SPC (L01EB02 erlotinib) Prescription only (POM)
Erlotinib Mylan 150 mg film-coated tablets SPC (L01EB02 erlotinib) Prescription only (POM)
Erlotinib Sandoz 100 mg film coated tablets SPC no longer supplied (L01EB02 erlotinib) –
Erlotinib Sandoz 150 mg film-coated tablets SPC no longer supplied (L01EB02 erlotinib) –

Other groups of the same level

Other names of the ATC group

Sources

  • Patient leaflets and SPCs: the MHRA product information (products.mhra.gov.uk) and the European Medicines Agency (EMA)
  • Active substances, ATC codes and legal categories: the NHS Dictionary of Medicines and Devices (dm+d), NHS Business Services Authority
  • World Health Organization (WHO): ATC/DDD classification, group L01E

Contains public sector information licensed under the Open Government Licence v3.0.

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