L01E Protein kinase inhibitors, antineoplastic and immunomodulating agents
ATC group of level 3 – pharmacological subgroup · in plain English: targeted cancer medicines (kinase inhibitors)
This site has the patient leaflet or the SPC of 353 medicines in this group and its subgroups.
- 300 prescription only (POM)
- 45 no longer supplied or not available
Place in the ATC classification
How to read ATC codes – what the levels mean and what a code does not tell you.
- L Antineoplastic and immunomodulating agents 1,791 medicines
- L01 Antineoplastic agents 1,025 medicines
-
L01E Protein kinase inhibitors, antineoplastic and immunomodulating agents 353 medicines
- L01EA BCR-ABL tyrosine kinase inhibitors 101 medicines
- L01EB Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors 40 medicines
- L01EC B-Raf serine-threonine kinase (BRAF) inhibitors 6 medicines
- L01ED Anaplastic lymphoma kinase (ALK) inhibitors 14 medicines
- L01EE Mitogen-activated protein kinase (MEK) inhibitors 10 medicines
- L01EF Cyclin-dependent kinase (CDK) inhibitors 13 medicines
- L01EG Mammalian target of rapamycin (mTOR) kinase inhibitors 27 medicines
- L01EH Human epidermal growth factor receptor 2 (HER2) tyrosine kinase inhibitors 4 medicines
- L01EJ Janus-associated kinase (JAK) inhibitors 18 medicines
- L01EK Vascular endothelial growth factor receptor (VEGFR) tyrosine kinase inhibitors 12 medicines
- L01EL Bruton's tyrosine kinase (BTK) inhibitors 8 medicines
- L01EM Phosphatidylinositol-3-kinase (Pi3K) inhibitors 6 medicines
- L01EX Other protein kinase inhibitors 94 medicines
-
L01E Protein kinase inhibitors, antineoplastic and immunomodulating agents 353 medicines
- L01 Antineoplastic agents 1,025 medicines
Active substances in the group
- Abemaciclib 3 medicines
- Acalabrutinib 1 medicine
- Afatinib 4 medicines
- Alectinib 1 medicine
- Alpelisib 3 medicines
- Avapritinib 5 medicines
- Axitinib 10 medicines
- Binimetinib 2 medicines
- Bosutinib 11 medicines
- Brigatinib 4 medicines
- Cabozantinib 8 medicines
- Ceritinib 2 medicines
- Cobimetinib 1 medicine
- Crizotinib 5 medicines
- Dabrafenib 3 medicines
- Dacomitinib 3 medicines
- Dasatinib 55 medicines
- Duvelisib 1 medicine
- Encorafenib 2 medicines
- Entrectinib 2 medicines
- Erlotinib 25 medicines
- Everolimus 26 medicines
- Fedratinib 1 medicine
- Gefitinib 6 medicines
- Gilteritinib 1 medicine
- Ibrutinib 5 medicines
- Idelalisib 2 medicines
- Imatinib 22 medicines
- Lapatinib 1 medicine
- Larotrectinib 3 medicines
- Lenvatinib 7 medicines
- Lorlatinib 2 medicines
- Midostaurin 1 medicine
- Neratinib 1 medicine
- Nilotinib 8 medicines
- Nintedanib 12 medicines
- Osimertinib 2 medicines
- Palbociclib 9 medicines
- Pazopanib 4 medicines
- Pemigatinib 1 medicine
- Ponatinib 5 medicines
- Quizartinib 1 medicine
- Regorafenib 1 medicine
- Ribociclib 1 medicine
- Ripretinib 1 medicine
- Ruxolitinib 16 medicines
- Selumetinib 4 medicines
- Sorafenib 6 medicines
- Sunitinib 37 medicines
- Temsirolimus 1 medicine
- Tepotinib 1 medicine
- Tivozanib 2 medicines
- Trametinib 3 medicines
- Tucatinib 2 medicines
- Vandetanib 2 medicines
- Vemurafenib 1 medicine
- Zanubrutinib 2 medicines
Medicines in the group and its subgroups
Other groups of the same level
- L01A Alkylating agents 123 medicines
- L01B Antimetabolites 182 medicines
- L01C Plant alkaloids and other natural products, antineoplastic drugs 97 medicines
- L01D Cytotoxic antibiotics and related substances 42 medicines
- L01X Other antineoplastic agents 225 medicines
Other names of the ATC group
- German: L01E Proteinkinase-Inhibitoren
- German: L01E Proteinkinase-Inhibitoren
- Italian: L01E Inibitori della protein chinasi
- Turkish: L01E PROTEİN KİNAZ İNHİBİTÖRLERİ, ANTİNEOPLASTİK VE İMMUNOMODÜLATÖR AJANLAR
- Czech: L01E Inhibitory proteinkináz
- Slovak: L01E Inhibítory proteínkinázy
- German (Switzerland): L01E Proteinkinase-Inhibitoren
- Italian (Switzerland): L01E Inibitori della protein chinasi
- Dutch: L01E Proteïnekinaseremmers, oncolytica en immunomodulerende middelen
- English (Canada): L01E Protein kinase inhibitors, antineoplastic and immunomodulating agents
Sources
- Patient leaflets and SPCs: the MHRA product information (products.mhra.gov.uk) and the European Medicines Agency (EMA)
- Active substances, ATC codes and legal categories: the NHS Dictionary of Medicines and Devices (dm+d), NHS Business Services Authority
- World Health Organization (WHO): ATC/DDD classification, group L01E
Contains public sector information licensed under the Open Government Licence v3.0.
Ask your doctor or pharmacist which medicine is right for you.