Medicines by ATC code L01EX Other protein kinase inhibitors

Place in the ATC classification

L Antineoplastic and immunomodulating agents 1,791 medicines
1. L01 Antineoplastic agents 1,025 medicines
  1. L01E Protein kinase inhibitors, antineoplastic and immunomodulating agents 353 medicines
    1. L01EX Other protein kinase inhibitors 94 medicines
      1. L01EX01 sunitinib 37 medicines
      2. L01EX02 sorafenib 6 medicines
      3. L01EX03 pazopanib 4 medicines
      4. L01EX04 vandetanib 2 medicines
      5. L01EX05 regorafenib 1 medicine
      6. L01EX07 cabozantinib 8 medicines
      7. L01EX08 lenvatinib 7 medicines
      8. L01EX09 nintedanib 12 medicines
      9. L01EX10 midostaurin 1 medicine
      10. L01EX11 quizartinib 1 medicine
      11. L01EX12 larotrectinib 3 medicines
      12. L01EX13 gilteritinib 1 medicine
      13. L01EX14 entrectinib 2 medicines
      14. L01EX17 capmatinib 1 medicine
      15. L01EX18 avapritinib 5 medicines
      16. L01EX19 ripretinib 1 medicine
      17. L01EX20 pemigatinib 1 medicine
      18. L01EX21 tepotinib 1 medicine

3 more subgroups have no medicine with a leaflet on this site.

Active substances in the group

Avapritinib 5 medicines
Cabozantinib 8 medicines
Entrectinib 2 medicines
Gilteritinib 1 medicine
Larotrectinib 3 medicines
Lenvatinib 7 medicines
Midostaurin 1 medicine
Nintedanib 12 medicines
Pazopanib 4 medicines
Pemigatinib 1 medicine
Quizartinib 1 medicine
Regorafenib 1 medicine
Ripretinib 1 medicine
Sorafenib 6 medicines
Sunitinib 37 medicines
Tepotinib 1 medicine
Vandetanib 2 medicines

Medicines in the group and its subgroups

Medicine	Legal category
Ayvakyt 100 mg film-coated tablets SPC (L01EX18 avapritinib)	Prescription only (POM)
Ayvakyt 200 mg film-coated tablets SPC (L01EX18 avapritinib)	Prescription only (POM)
Ayvakyt 25 mg film-coated tablets SPC (L01EX18 avapritinib)	Prescription only (POM)
Ayvakyt 300 mg film-coated tablets SPC (L01EX18 avapritinib)	Prescription only (POM)
Ayvakyt 50 mg film-coated tablets (L01EX18 avapritinib)	Prescription only (POM)
Cabometyx 20 mg film-coated tablets SPC (L01EX07 cabozantinib)	Prescription only (POM)
Cabometyx 40 mg film-coated tablets (L01EX07 cabozantinib)	Prescription only (POM)
Cabometyx 60 mg film-coated tablets SPC (L01EX07 cabozantinib)	Prescription only (POM)
Cabozantinib 20 mg film-coated tablets (L01EX07 cabozantinib)	Prescription only (POM)
Cabozantinib 40 mg film-coated tablets (L01EX07 cabozantinib)	Prescription only (POM)
Cabozantinib 60 mg film-coated tablets (L01EX07 cabozantinib)	Prescription only (POM)
Cabozantinib Ipsen 40 mg film-coated tablets (L01EX07 cabozantinib)	Prescription only (POM)
Caprelsa 100 mg film coated tablets SPC (L01EX04 vandetanib)	Prescription only (POM)
Caprelsa 300 mg film coated tablets SPC (L01EX04 vandetanib)	Prescription only (POM)
Cometriq 20 mg hard capsules SPC (L01EX07 cabozantinib)	Prescription only (POM)
Kisplyx 10 mg hard capsules SPC (L01EX08 lenvatinib)	Prescription only (POM)
Kisplyx 4 mg hard capsules SPC (L01EX08 lenvatinib)	Prescription only (POM)
Lenvatinib 10 mg hard capsules SPC (L01EX08 lenvatinib)	Prescription only (POM)
Lenvatinib 4 mg hard capsules SPC (L01EX08 lenvatinib)	Prescription only (POM)
Lenvatinib Torrent 10 mg hard capsules SPC (L01EX08 lenvatinib)	Prescription only (POM)
Lenvima 10 mg hard capsules SPC (L01EX08 lenvatinib)	Prescription only (POM)
Lenvima 4 mg hard capsules (L01EX08 lenvatinib)	Prescription only (POM)
Nexavar 200 mg film-coated tablets SPC (L01EX02 sorafenib)	Prescription only (POM)
Nintedanib 100 mg soft capsules SPC (L01EX09 nintedanib)	Prescription only (POM)
Nintedanib 150 mg soft capsules SPC (L01EX09 nintedanib)	Prescription only (POM)
Nintedanib Advanz Pharma 150 mg soft capsules SPC (L01EX09 nintedanib)	Prescription only (POM)
Nintedanib Olpha 100 mg soft capsules SPC (L01EX09 nintedanib)	Prescription only (POM)
Nintedanib Olpha 150 mg soft capsules SPC (L01EX09 nintedanib)	Prescription only (POM)
Nintedanib Sandoz 100 mg soft capsules SPC (L01EX09 nintedanib)	Prescription only (POM)
Nintedanib Sandoz 150 mg soft capsules SPC (L01EX09 nintedanib)	Prescription only (POM)
Ofev 100 mg soft capsules SPC (L01EX09 nintedanib)	Prescription only (POM)
Ofev 150 mg soft capsules SPC (L01EX09 nintedanib)	Prescription only (POM)
Ofev 25 mg soft capsules SPC (L01EX09 nintedanib)	Prescription only (POM)
Pazopanib 200 mg film-coated tablets SPC (L01EX03 pazopanib)	Prescription only (POM)
Pazopanib 400 mg film-coated tablets SPC (L01EX03 pazopanib)	Prescription only (POM)
Pemazyre 4.5 mg tablets SPC (L01EX20 pemigatinib)	Prescription only (POM)
Qinlock 50 mg tablets SPC (L01EX19 ripretinib)	Prescription only (POM)
Rozlytrek 100 mg hard capsules SPC (L01EX14 entrectinib)	Prescription only (POM)
Rozlytrek 200 mg hard capsules SPC (L01EX14 entrectinib)	Prescription only (POM)
Rydapt 25 mg soft capsules SPC (L01EX10 midostaurin)	Prescription only (POM)
Sorafenib 200 mg film-coated tablets SPC (L01EX02 sorafenib)	Prescription only (POM)
Sorafenib Sandoz 200 mg film-coated tablets SPC no longer supplied (L01EX02 sorafenib)	–
Sorafenib Teva 200 mg film-coated tablets SPC (L01EX02 sorafenib)	Prescription only (POM)
Sorafenib Torrent 200 mg film-coated tablets SPC (L01EX02 sorafenib)	Prescription only (POM)
Sorafenib Zentiva 200 mg film-coated tablets SPC (L01EX02 sorafenib)	Prescription only (POM)
Stivarga 40 mg film-coated tablets SPC (L01EX05 regorafenib)	Prescription only (POM)
Sunitinib 12.5 mg hard capsules SPC (L01EX01 sunitinib)	Prescription only (POM)
Sunitinib 25 mg hard capsules SPC (L01EX01 sunitinib)	Prescription only (POM)
Sunitinib 37.5 mg hard capsules SPC no longer supplied (L01EX01 sunitinib)	–
Sunitinib 50 mg hard capsules SPC (L01EX01 sunitinib)	Prescription only (POM)
Sunitinib Accord 12.5 mg hard capsules SPC (L01EX01 sunitinib)	Prescription only (POM)
Sunitinib Accord 25 mg hard capsules SPC (L01EX01 sunitinib)	Prescription only (POM)
Sunitinib Accord 37.5 mg hard capsules SPC no longer supplied (L01EX01 sunitinib)	–
Sunitinib Accord 50 mg hard capsules SPC (L01EX01 sunitinib)	Prescription only (POM)
Sunitinib Bluepharma 12.5 mg, hard capsule SPC (L01EX01 sunitinib)	Prescription only (POM)
Sunitinib Bluepharma 25 mg, hard capsule SPC (L01EX01 sunitinib)	Prescription only (POM)
Sunitinib Bluepharma 37.5 mg hard capsule SPC not available (L01EX01 sunitinib)	–
Sunitinib Bluepharma 50 mg, hard capsule SPC (L01EX01 sunitinib)	Prescription only (POM)
Sunitinib Cipla 12.5 mg hard capsules SPC (L01EX01 sunitinib)	Prescription only (POM)
Sunitinib Cipla 25 mg hard capsules SPC (L01EX01 sunitinib)	Prescription only (POM)
Sunitinib Cipla 50 mg hard capsules (L01EX01 sunitinib)	Prescription only (POM)
Sunitinib DR. Reddys 12.5 mg hard capsules SPC (L01EX01 sunitinib)	Prescription only (POM)
Sunitinib DR. Reddys 25 mg hard capsules SPC (L01EX01 sunitinib)	Prescription only (POM)
Sunitinib Egis 12.5 mg hard capsules SPC (L01EX01 sunitinib)	Prescription only (POM)
Sunitinib Egis 25 mg hard capsules SPC (L01EX01 sunitinib)	Prescription only (POM)
Sunitinib Mylan 12.5 mg hard capsules SPC (L01EX01 sunitinib)	Prescription only (POM)
Sunitinib Mylan 25 mg hard capsules SPC (L01EX01 sunitinib)	Prescription only (POM)
Sunitinib Mylan 37.5 mg hard capsules SPC not available (L01EX01 sunitinib)	–
Sunitinib Mylan 50 mg hard capsules SPC (L01EX01 sunitinib)	Prescription only (POM)
Sunitinib Piramal 12.5 mg hard capsules SPC (L01EX01 sunitinib)	Prescription only (POM)
Sunitinib Piramal 25 mg hard capsules SPC (L01EX01 sunitinib)	Prescription only (POM)
Sunitinib Piramal 37.5 mg hard capsules SPC not available (L01EX01 sunitinib)	–
Sunitinib Piramal 50 mg hard capsules SPC (L01EX01 sunitinib)	Prescription only (POM)
Sunitinib Sandoz 12.5 mg hard capsules SPC (L01EX01 sunitinib)	Prescription only (POM)
Sunitinib Stada 12.5 mg hard capsules SPC (L01EX01 sunitinib)	Prescription only (POM)
Sunitinib Stada 25 mg hard capsules SPC (L01EX01 sunitinib)	Prescription only (POM)
Sunitinib Zentiva 12.5 mg hard capsules SPC no longer supplied (L01EX01 sunitinib)	–
Sunitinib Zentiva 25 mg hard capsules SPC no longer supplied (L01EX01 sunitinib)	–
Sunitinib Zentiva 37.5 mg hard capsules SPC not available (L01EX01 sunitinib)	–
Sunitinib Zentiva 50 mg hard capsules SPC no longer supplied (L01EX01 sunitinib)	–
Sutent 12.5 mg hard capsules SPC (L01EX01 sunitinib)	Prescription only (POM)
Sutent 25 mg hard capsules SPC (L01EX01 sunitinib)	Prescription only (POM)
Sutent 50 mg hard capsules SPC (L01EX01 sunitinib)	Prescription only (POM)
Tabrecta 200 mg film-coated tablets SPC (L01EX17 capmatinib)	–
Tepmetko 225 mg film-coated tablets SPC (L01EX21 tepotinib)	Prescription only (POM)
Vanflyta 26.5 mg film-coated tablets SPC (L01EX11 quizartinib)	Prescription only (POM)
Vargatef 100 mg soft capsules SPC (L01EX09 nintedanib)	Prescription only (POM)
Vargatef 150 mg soft capsules SPC (L01EX09 nintedanib)	Prescription only (POM)
Vitrakvi 100 mg hard capsules SPC (L01EX12 larotrectinib)	Prescription only (POM)
Vitrakvi 20 mg / ml oral solution SPC (L01EX12 larotrectinib)	–
Vitrakvi 25 mg hard capsules SPC (L01EX12 larotrectinib)	Prescription only (POM)
Votrient 200 mg film-coated tablets SPC (L01EX03 pazopanib)	Prescription only (POM)
Votrient 400 mg film-coated tablets SPC (L01EX03 pazopanib)	Prescription only (POM)
Xospata 40 mg film-coated tablets SPC (L01EX13 gilteritinib)	Prescription only (POM)

Other groups of the same level

L01EA BCR-ABL tyrosine kinase inhibitors 101 medicines
L01EB Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors 40 medicines
L01EC B-Raf serine-threonine kinase (BRAF) inhibitors 6 medicines
L01ED Anaplastic lymphoma kinase (ALK) inhibitors 14 medicines
L01EE Mitogen-activated protein kinase (MEK) inhibitors 10 medicines
L01EF Cyclin-dependent kinase (CDK) inhibitors 13 medicines
L01EG Mammalian target of rapamycin (mTOR) kinase inhibitors 27 medicines
L01EH Human epidermal growth factor receptor 2 (HER2) tyrosine kinase inhibitors 4 medicines
L01EJ Janus-associated kinase (JAK) inhibitors 18 medicines
L01EK Vascular endothelial growth factor receptor (VEGFR) tyrosine kinase inhibitors 12 medicines
L01EL Bruton's tyrosine kinase (BTK) inhibitors 8 medicines
L01EM Phosphatidylinositol-3-kinase (Pi3K) inhibitors 6 medicines

Other names of the ATC group

German: L01EX Andere Proteinkinase-Inhibitoren
German: L01EX Andere Proteinkinase-Inhibitoren
Italian: L01EX Altri inbitori della proteina chinasi
Turkish: L01EX ATC'deki diğer protein kinaz inhibitörleri
Czech: L01EX Jiné inhibitory proteinkináz

Sources

Patient leaflets and SPCs: the MHRA product information (products.mhra.gov.uk) and the European Medicines Agency (EMA)
Active substances, ATC codes and legal categories: the NHS Dictionary of Medicines and Devices (dm+d), NHS Business Services Authority
World Health Organization (WHO): ATC/DDD classification, group L01EX

Contains public sector information licensed under the Open Government Licence v3.0.

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