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L01B Antimetabolites

ATC group of level 3 – pharmacological subgroup · in plain English: cancer medicines that stop cells from dividing

This site has the patient leaflet or the SPC of 182 medicines in this group and its subgroups.

Place in the ATC classification

  1. L Antineoplastic and immunomodulating agents 1,791 medicines
    1. L01 Antineoplastic agents 1,025 medicines
      1. L01B Antimetabolites 182 medicines
        1. L01BA Folic acid analogs, antimetabolites 79 medicines
        2. L01BB Purine analogs, antimetabolites antineoplastic 25 medicines
        3. L01BC Pyrimidine analogues, antineoplastic antimetabolites 78 medicines

Active substances in the group

Medicines in the group and its subgroups

MedicineLegal category
Actikerall 5 mg / g + 100 mg / g cutaneous solution SPC (L01BC52 fluorouracil, combinations) Prescription only (POM)
Alimta 100 mg powder for concentrate for solution for infusion SPC (L01BA04 pemetrexed) Prescription only (POM)
Alimta 500 mg powder for concentrate for solution for infusion SPC (L01BA04 pemetrexed) Prescription only (POM)
Armisarte (previously Pemetrexed Actavis) SPC (L01BA04 pemetrexed) –
Atriance 5 mg / ml solution for infusion SPC (L01BB07 nelarabine) Prescription only (POM)
Azacitidine 200 mg film-coated tablets SPC (L01BC07 azacitidine) Prescription only (POM)
Azacitidine 300 mg film-coated tablets SPC (L01BC07 azacitidine) Prescription only (POM)
Azacitidine Accord SPC (L01BC07 azacitidine) –
Azacitidine Accord 25 mg/ml powder for suspension for injection SPC (L01BC07 azacitidine) –
Azacitidine Betapharm 25 mg / ml powder for suspension for injection SPC (L01BC07 azacitidine) –
Azacitidine Celgene SPC (L01BC07 azacitidine) –
Azacitidine Celgene 25 mg / ml powder for suspension for injection SPC (L01BC07 azacitidine) –
Azacitidine Kabi 25 mg/ml powder for suspension for injection SPC (L01BC07 azacitidine) –
Azacitidine Mylan SPC (L01BC07 azacitidine) –
Azacitidine Sandoz 25 mg / ml powder for suspension for injection SPC (L01BC07 azacitidine) –
Azacitidine Seacross 25 mg / ml powder for suspension for injection SPC (L01BC07 azacitidine) –
Azacitidine Tillomed 25 mg / ml powder for suspension for injection SPC (L01BC07 azacitidine) –
Azapan 25 mg/ml, powder for suspension for injection SPC (L01BC07 azacitidine) –
Capecitabine 150 mg film-coated tablets SPC (L01BC06 capecitabine) Prescription only (POM)
Capecitabine 500 mg film-coated tablets SPC no longer supplied (L01BC06 capecitabine) –
Capecitabine Accord 150 mg film-coated tablets SPC (L01BC06 capecitabine) Prescription only (POM)
Capecitabine Accord 300 mg film-coated tablets (L01BC06 capecitabine) Prescription only (POM)
Capecitabine Accord 500 mg film-coated tablets SPC (L01BC06 capecitabine) Prescription only (POM)
Capecitabine DR Reddys 500 mg film coated tablets (L01BC06 capecitabine) Prescription only (POM)
Capecitabine DR. Reddys 150 mg film-coated tablets SPC no longer supplied (L01BC06 capecitabine) –
Capecitabine Glenmark 150 mg film-coated tablets SPC (L01BC06 capecitabine) Prescription only (POM)
Capecitabine Glenmark 500 mg film-coated tablets SPC (L01BC06 capecitabine) Prescription only (POM)
Capecitabine Krka 500 mg film-coated tablets SPC (L01BC06 capecitabine) Prescription only (POM)
Capecitabine Medac SPC (L01BC06 capecitabine) –
Capecitabine Mylan 150 mg film-coated tablets SPC no longer supplied (L01BC06 capecitabine) –
Capecitabine Mylan 500 mg film-coated tablets no longer supplied (L01BC06 capecitabine) –
Capecitabine Sandoz 150 mg film-coated tablets SPC (L01BC06 capecitabine) Prescription only (POM)
Capecitabine Sandoz 500 mg film-coated tablets (L01BC06 capecitabine) Prescription only (POM)
Capecitabine SUN SPC (L01BC06 capecitabine) –
Capecitabine Teva 150 mg film-coated tablets SPC (L01BC06 capecitabine) Prescription only (POM)
Capecitabine Teva 500 mg film-coated tablets SPC (L01BC06 capecitabine) Prescription only (POM)
Capecitabine Waverley 150 mg film-coated tablets SPC (L01BC06 capecitabine) Prescription only (POM)
Capecitabine Waverley 500 mg film-coated tablets SPC (L01BC06 capecitabine) Prescription only (POM)
Capecitabine Zentiva 150 mg film-coated tablets SPC no longer supplied (L01BC06 capecitabine) –
Capecitabine Zentiva 500 mg film-coated tablets SPC no longer supplied (L01BC06 capecitabine) –
Ciambra SPC (L01BA04 pemetrexed) –
Ciambra 100 mg powder for concentrate for solution for infusion SPC (L01BA04 pemetrexed) –
Clofarabine 1 mg / ml concentrate for solution for infusion SPC (L01BB06 clofarabine) Prescription only (POM)
Clofarabine Neon Healthcare 1 mg / ml concentrate for solution for infusion (L01BB06 clofarabine) Prescription only (POM)
Clofarabine Sandoz 1 mg / ml concentrate for solution for infusion SPC (L01BB06 clofarabine) Prescription only (POM)
Clofarabine Teva 1 mg / ml concentrate for solution for infusion SPC (L01BB06 clofarabine) Prescription only (POM)
Cytarabine 100 mg / ml injection SPC (L01BC01 cytarabine) –
Cytarabine 100 mg / ml solution for injection or infusion SPC (L01BC01 cytarabine) –
Cytarabine 20 mg / ml solution for injection/infusion SPC (L01BC01 cytarabine) Prescription only (POM)
Cytarabine 20 mg/ml injection SPC (L01BC01 cytarabine) –
Dacogen 50 mg powder for concentrate for solution for infusion SPC (L01BC08 decitabine) Prescription only (POM)
Decitabine 50 mg powder for concentrate for solution for infusion SPC (L01BC08 decitabine) Prescription only (POM)
DepoCyte no longer supplied (L01BC01 cytarabine) –
Ecansya (previously Capecitabine Krka) SPC (L01BC06 capecitabine) –
Ecansya 150 mg film-coated tablets SPC (L01BC06 capecitabine) Prescription only (POM)
Ecansya 300 mg film-coated tablets SPC (L01BC06 capecitabine) Prescription only (POM)
Efudix 5% cream (L01BC02 fluorouracil) Prescription only (POM)
Efudix 5% w/w cream (L01BC02 fluorouracil) Prescription only (POM)
Efudix cream SPC (L01BC02 fluorouracil) Prescription only (POM)
Evoltra SPC no longer supplied (L01BB06 clofarabine) –
Evoltra 1 mg / ml Concentration for solution for infusion no longer supplied (L01BB06 clofarabine) –
Fludara 50 mg powder for solution for injection or infusion SPC no longer supplied (L01BB05 fludarabine) –
Fludara oral 10 mg film-coated tablets SPC (L01BB05 fludarabine) Prescription only (POM)
Fludarabine 25 mg / ml concentrate for solution for injection or infusion SPC (L01BB05 fludarabine) Prescription only (POM)
Fludarabine 50 mg powder for solution for injection or infusion SPC (L01BB05 fludarabine) –
Fludarabine Phosphate 25 mg / ml concentrate for solution for injection or infusion SPC (L01BB05 fludarabine) Prescription only (POM)
Fludarabine Phosphate 25 mg/ml concentrate for solution for injection/infusion SPC (L01BB05 fludarabine) Prescription only (POM)
Fluorouracil 25 mg / ml injection SPC (L01BC02 fluorouracil) –
Fluorouracil 5% w/w cream, Efudix 5% w/w cream (L01BC02 fluorouracil) Prescription only (POM)
Fluorouracil 50 mg / ml injection SPC no longer supplied (L01BC02 fluorouracil) –
Fluorouracil 50 mg/ml solution for injection/infusion SPC (L01BC02 fluorouracil) –
Fluorouracil 50 mg/ml, solution for injection or infusion (L01BC02 fluorouracil) –
Fluorouracil injection 25 mg/ml, solution for injection SPC (L01BC02 fluorouracil) –
Fluorouracil injection 50 mg / ml solution for injection (L01BC02 fluorouracil) –
Gemcitabine 1 g powder for solution for infusion (L01BC05 gemcitabine) –
Gemcitabine 10 mg / ml solution for infusion SPC (L01BC05 gemcitabine) –
Gemcitabine 100 mg/ml concentrate for solution for infusion SPC (L01BC05 gemcitabine) –
Gemcitabine 1000 mg powder for solution for infusion SPC (L01BC05 gemcitabine) –
Gemcitabine 2 g powder for solution for infusion SPC (L01BC05 gemcitabine) Prescription only (POM)
Gemcitabine 200 mg powder for solution for infusion SPC (L01BC05 gemcitabine) –
Gemcitabine 38 mg / ml concentrate for solution for infusion SPC (L01BC05 gemcitabine) –
Gemcitabine 38 mg / ml powder for solution for infusion SPC (L01BC05 gemcitabine) –
Gemcitabine 40 mg/ml concentrate for solution for infusion (L01BC05 gemcitabine) –
Hanixol 50 mg tablets SPC (L01BB02 mercaptopurine) Prescription only (POM)
Ivozall SPC (L01BB06 clofarabine) –
Jylamvo 2 mg/ml oral solution (L01BA01 methotrexate) Prescription only (POM)
Leustat subcutaneous 2 mg/ml solution for injection SPC (L01BB04 cladribine) –
Litak 2 mg/ml solution for injection SPC (L01BB04 cladribine) Prescription only (POM)
Lonsurf SPC (L01BC Pyrimidine analogues, antineoplastic antimetabolites) Prescription only (POM)
Lonsurf 15 mg / 6.14 mg film-coated tablets SPC (L01BC59 trifluridine, combinations) Prescription only (POM)
Mercaptopurine 50 mg tablets SPC (L01BB02 mercaptopurine) Prescription only (POM)
Mercaptopurine 50 mg tablets,Puri-nethol 50 mg tablets (L01BB02 mercaptopurine) Prescription only (POM)
Mercaptopurine Silver Pharma 50 mg tablets SPC (L01BB02 mercaptopurine) –
Methotrexate 100 mg / ml injection SPC (L01BA01 methotrexate) Prescription only (POM)
Methotrexate 100 mg / ml injection BP (L01BA01 methotrexate) Prescription only (POM)
Methotrexate 100 mg / ml solution for injection SPC (L01BA01 methotrexate) Prescription only (POM)
Methotrexate 100 mg/ml concentrate for solution for infusion SPC (L01BA01 methotrexate) Prescription only (POM)
Methotrexate 2.5 mg / ml injection SPC (L01BA01 methotrexate) Prescription only (POM)
Methotrexate 2.5 mg / ml solution for injection SPC (L01BA01 methotrexate) Prescription only (POM)
Methotrexate 25 mg / ml solution for injection SPC (L01BA01 methotrexate) –

Other groups of the same level

Other names of the ATC group

Sources

  • Patient leaflets and SPCs: the MHRA product information (products.mhra.gov.uk) and the European Medicines Agency (EMA)
  • Active substances, ATC codes and legal categories: the NHS Dictionary of Medicines and Devices (dm+d), NHS Business Services Authority
  • World Health Organization (WHO): ATC/DDD classification, group L01B

Contains public sector information licensed under the Open Government Licence v3.0.

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