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L01EF Cyclin-dependent kinase (CDK) inhibitors

ATC group of level 4 – chemical subgroup · in plain English: targeted cancer medicines (kinase inhibitors)

This site has the patient leaflet or the SPC of 13 medicines in this group and its subgroups.

Place in the ATC classification

How to read ATC codes – what the levels mean and what a code does not tell you.

  1. L Antineoplastic and immunomodulating agents 1,791 medicines
    1. L01 Antineoplastic agents 1,025 medicines
      1. L01E Protein kinase inhibitors, antineoplastic and immunomodulating agents 353 medicines
        1. L01EF Cyclin-dependent kinase (CDK) inhibitors 13 medicines
          1. L01EF01 palbociclib 9 medicines
          2. L01EF02 ribociclib 1 medicine
          3. L01EF03 abemaciclib 3 medicines

Active substances in the group

Medicines in the group and its subgroups

MedicineLegal category
Ibrance 100 mg film-coated tablets SPC (L01EF01 palbociclib) Prescription only (POM)
Ibrance 100 mg hard capsules not available (L01EF01 palbociclib) –
Ibrance 125 mg film-coated tablets SPC (L01EF01 palbociclib) Prescription only (POM)
Ibrance 125 mg hard capsules not available (L01EF01 palbociclib) –
Ibrance 75 mg film-coated tablets SPC (L01EF01 palbociclib) Prescription only (POM)
Ibrance 75 mg hard capsules SPC no longer supplied (L01EF01 palbociclib) –
Kisqali 200 mg film-coated tablets SPC (L01EF02 ribociclib) Prescription only (POM)
Palbociclib 100 mg film-coated tablets SPC (L01EF01 palbociclib) Prescription only (POM)
Palbociclib 125 mg film-coated tablets SPC (L01EF01 palbociclib) Prescription only (POM)
Palbociclib 75 mg film-coated tablets (L01EF01 palbociclib) Prescription only (POM)
Verzenios 100 mg film-coated tablets SPC (L01EF03 abemaciclib) Prescription only (POM)
Verzenios 150 mg film-coated tablets SPC (L01EF03 abemaciclib) Prescription only (POM)
Verzenios 50 mg film-coated tablets SPC (L01EF03 abemaciclib) Prescription only (POM)

Other groups of the same level

Other names of the ATC group

Sources

  • Patient leaflets and SPCs: the MHRA product information (products.mhra.gov.uk) and the European Medicines Agency (EMA)
  • Active substances, ATC codes and legal categories: the NHS Dictionary of Medicines and Devices (dm+d), NHS Business Services Authority
  • World Health Organization (WHO): ATC/DDD classification, group L01EF

Contains public sector information licensed under the Open Government Licence v3.0.

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