Medicines by ATC code L01EA BCR-ABL tyrosine kinase inhibitors

Place in the ATC classification

L Antineoplastic and immunomodulating agents 1,791 medicines
1. L01 Antineoplastic agents 1,025 medicines
  1. L01E Protein kinase inhibitors, antineoplastic and immunomodulating agents 353 medicines
    1. L01EA BCR-ABL tyrosine kinase inhibitors 101 medicines
      1. L01EA01 imatinib 22 medicines
      2. L01EA02 dasatinib 55 medicines
      3. L01EA03 nilotinib 8 medicines
      4. L01EA04 bosutinib 11 medicines
      5. L01EA05 ponatinib 5 medicines

Active substances in the group

Bosutinib 11 medicines
Dasatinib 55 medicines
Imatinib 22 medicines
Nilotinib 8 medicines
Ponatinib 5 medicines

Medicines in the group and its subgroups

Medicine	Legal category
Bosulif 100 mg film coated tablets (L01EA04 bosutinib)	Prescription only (POM)
Bosulif 100 mg hard capsules SPC (L01EA04 bosutinib)	Prescription only (POM)
Bosulif 400 mg film-coated tablets SPC (L01EA04 bosutinib)	Prescription only (POM)
Bosulif 50 mg hard capsules SPC (L01EA04 bosutinib)	Prescription only (POM)
Bosulif 500 mg film coated tablets (L01EA04 bosutinib)	Prescription only (POM)
Bosutinib 100 mg film coated tablets SPC (L01EA04 bosutinib)	Prescription only (POM)
Bosutinib 400 mg film-coated tablets (L01EA04 bosutinib)	Prescription only (POM)
Bosutinib 500 mg film-coated tablets (L01EA04 bosutinib)	Prescription only (POM)
Bosutinib Sandoz 100 mg film coated tablet (L01EA04 bosutinib)	Prescription only (POM)
Bosutinib Sandoz 400 mg film coated tablet (L01EA04 bosutinib)	Prescription only (POM)
Bosutinib Sandoz 500 mg film coated tablet (L01EA04 bosutinib)	Prescription only (POM)
Dasatinib 100 mg film-coated tablets SPC (L01EA02 dasatinib)	Prescription only (POM)
Dasatinib 140 mg film-coated tablets SPC (L01EA02 dasatinib)	Prescription only (POM)
Dasatinib 20 mg film-coated tablets SPC (L01EA02 dasatinib)	Prescription only (POM)
Dasatinib 50 mg film-coated tablets SPC (L01EA02 dasatinib)	Prescription only (POM)
Dasatinib 70 mg film-coated tablets not available (L01EA02 dasatinib)	–
Dasatinib 80 mg film-coated tablets SPC (L01EA02 dasatinib)	Prescription only (POM)
Dasatinib Accord 140 mg film-coated tablets (L01EA02 dasatinib)	Prescription only (POM)
Dasatinib Accord 50 mg film-coated tablets (L01EA02 dasatinib)	Prescription only (POM)
Dasatinib Accord 70 mg film-coated tablets not available (L01EA02 dasatinib)	–
Dasatinib Accord 80 mg film-coated tablets (L01EA02 dasatinib)	Prescription only (POM)
Dasatinib Sandoz 100 mg film-coated tablets SPC (L01EA02 dasatinib)	Prescription only (POM)
Dasatinib Sandoz 140 mg film-coated tablets SPC (L01EA02 dasatinib)	Prescription only (POM)
Dasatinib Sandoz 20 mg film-coated tablets SPC (L01EA02 dasatinib)	Prescription only (POM)
Dasatinib Sandoz 50 mg film-coated tablets SPC (L01EA02 dasatinib)	Prescription only (POM)
Dasatinib Sandoz 70 mg film-coated tablets SPC not available (L01EA02 dasatinib)	–
Dasatinib Sandoz 80 mg film-coated tablets SPC (L01EA02 dasatinib)	Prescription only (POM)
Dasatinib Stada 100 mg film-coated tablets SPC no longer supplied (L01EA02 dasatinib)	–
Dasatinib Stada 140 mg film-coated tablets SPC no longer supplied (L01EA02 dasatinib)	–
Dasatinib Stada 20 mg film-coated tablets SPC (L01EA02 dasatinib)	Prescription only (POM)
Dasatinib Stada 50 mg film-coated tablets SPC no longer supplied (L01EA02 dasatinib)	–
Dasatinib Stada 80 mg film-coated tablets SPC no longer supplied (L01EA02 dasatinib)	–
Dasatinib Teva 100 mg film-coated tablets SPC (L01EA02 dasatinib)	Prescription only (POM)
Dasatinib Teva 20 mg film-coated tablets SPC (L01EA02 dasatinib)	Prescription only (POM)
Dasatinib Teva 50 mg film-coated tablets SPC (L01EA02 dasatinib)	Prescription only (POM)
Dasatinib Teva 70 mg film-coated tablets SPC not available (L01EA02 dasatinib)	–
Dasatinib Teva 80 mg film-coated tablets SPC (L01EA02 dasatinib)	Prescription only (POM)
Dasatinib Tiefenbacher 100 mg film-coated tablets SPC (L01EA02 dasatinib)	Prescription only (POM)
Dasatinib Tiefenbacher 140 mg film-coated tablets SPC (L01EA02 dasatinib)	Prescription only (POM)
Dasatinib Tiefenbacher 50 mg film-coated tablets SPC (L01EA02 dasatinib)	Prescription only (POM)
Dasatinib Tiefenbacher 70 mg film-coated tablets SPC not available (L01EA02 dasatinib)	–
Dasatinib Tiefenbacher 80 mg film-coated tablets SPC (L01EA02 dasatinib)	Prescription only (POM)
Dasatinib Tillomed 100 mg film-coated tablets SPC (L01EA02 dasatinib)	Prescription only (POM)
Dasatinib Tillomed 140 mg film-coated tablets SPC (L01EA02 dasatinib)	Prescription only (POM)
Dasatinib Tillomed 20 mg film-coated tablets SPC (L01EA02 dasatinib)	Prescription only (POM)
Dasatinib Tillomed 50 mg film-coated tablets SPC (L01EA02 dasatinib)	Prescription only (POM)
Dasatinib Tillomed 70 mg film-coated tablets SPC not available (L01EA02 dasatinib)	–
Dasatinib Tillomed 80 mg film-coated tablets SPC (L01EA02 dasatinib)	Prescription only (POM)
Dasatinib Zentiva 100 mg film-coated tablets (L01EA02 dasatinib)	Prescription only (POM)
Dasatinib Zentiva 140 mg film-coated tablets SPC no longer supplied (L01EA02 dasatinib)	–
Dasatinib Zentiva 20 mg film-coated tablets (L01EA02 dasatinib)	Prescription only (POM)
Dasatinib Zentiva 50 mg film-coated tablets SPC no longer supplied (L01EA02 dasatinib)	–
Dasatinib Zentiva 70 mg film-coated tablets not available (L01EA02 dasatinib)	–
Dasatinib Zentiva 80 mg film-coated tablets SPC (L01EA02 dasatinib)	Prescription only (POM)
Glivec 100 mg film-coated tablets (L01EA01 imatinib)	Prescription only (POM)
Glivec 400 mg film-coated tablets SPC (L01EA01 imatinib)	Prescription only (POM)
Iclusig SPC no longer supplied (L01EA05 ponatinib)	–
Iclusig 15 mg film-coated tablets (L01EA05 ponatinib)	Prescription only (POM)
Iclusig 30 mg film-coated tablets SPC (L01EA05 ponatinib)	Prescription only (POM)
Iclusig 45 mg film-coated tablets SPC no longer supplied (L01EA05 ponatinib)	–
Imatinib 100 mg capsules hard SPC (L01EA01 imatinib)	Prescription only (POM)
Imatinib 100 mg dispersible tablets (L01EA01 imatinib)	Prescription only (POM)
Imatinib 100 mg film-coated tablets SPC (L01EA01 imatinib)	Prescription only (POM)
Imatinib 400 mg capsules hard SPC (L01EA01 imatinib)	Prescription only (POM)
Imatinib 400 mg film-coated tablets SPC (L01EA01 imatinib)	Prescription only (POM)
Imatinib 600 mg film-coated tablets SPC (L01EA01 imatinib)	Prescription only (POM)
Imatinib Accord 100 mg film coated tablets SPC (L01EA01 imatinib)	Prescription only (POM)
Imatinib Accord 400 mg film coated tablets SPC (L01EA01 imatinib)	Prescription only (POM)
Imatinib Actavis SPC (L01EA01 imatinib)	–
Imatinib Altan 100 mg hard capsules SPC (L01EA01 imatinib)	Prescription only (POM)
Imatinib DR. Reddys 100 mg capsules hard SPC (L01EA01 imatinib)	Prescription only (POM)
Imatinib DR. Reddys 400 mg capsules hard SPC (L01EA01 imatinib)	Prescription only (POM)
Imatinib Grindeks 100 mg hard capsules SPC (L01EA01 imatinib)	Prescription only (POM)
Imatinib Koanaa SPC (L01EA01 imatinib)	–
Imatinib Milpharm 100 mg film-coated tablets SPC (L01EA01 imatinib)	Prescription only (POM)
Imatinib Teva SPC (L01EA01 imatinib)	–
Imatinib Teva 400 mg film-coated tablets SPC (L01EA01 imatinib)	Prescription only (POM)
Imatinib Tillomed 100 mg film-coated tablets SPC (L01EA01 imatinib)	Prescription only (POM)
Nibix 100 mg capsule hard SPC no longer supplied (L01EA01 imatinib)	–
Nibix 400 mg hard capsules SPC no longer supplied (L01EA01 imatinib)	–
Nilotinib 150 mg hard capsules SPC (L01EA03 nilotinib)	Prescription only (POM)
Nilotinib 200 mg hard capsules SPC (L01EA03 nilotinib)	Prescription only (POM)
Nilotinib 50 mg hard capsules SPC (L01EA03 nilotinib)	Prescription only (POM)
Nilotinib Torrent 150 mg hard capsules SPC (L01EA03 nilotinib)	Prescription only (POM)
Nilotinib Torrent 200 mg hard capsules SPC (L01EA03 nilotinib)	Prescription only (POM)
Ponatinib Incyte 45 mg film-coated tablets SPC (L01EA05 ponatinib)	Prescription only (POM)
Sprycel 10 mg / ml powder for oral suspension SPC (L01EA02 dasatinib)	Prescription only (POM)
Sprycel 100 mg film-coated tablets SPC (L01EA02 dasatinib)	Prescription only (POM)
Sprycel 140 mg film-coated tablets SPC (L01EA02 dasatinib)	Prescription only (POM)
Sprycel 20 mg film-coated tablets SPC (L01EA02 dasatinib)	Prescription only (POM)
Sprycel 50 mg film coated tablet SPC (L01EA02 dasatinib)	Prescription only (POM)
Sprycel 80 mg film-coated tablets SPC (L01EA02 dasatinib)	Prescription only (POM)
Tasigna 150 mg hard capsules SPC (L01EA03 nilotinib)	Prescription only (POM)
Tasigna 200 mg hard capsules SPC (L01EA03 nilotinib)	Prescription only (POM)
Tasigna 50 mg hard capsules (L01EA03 nilotinib)	Prescription only (POM)
Uxil 110.6 mg film-coated tablets no longer supplied (L01EA02 dasatinib)	–
Uxil 15.8 mg film-coated tablets SPC no longer supplied (L01EA02 dasatinib)	–
Uxil 39.5 mg film-coated tablets SPC no longer supplied (L01EA02 dasatinib)	–
Uxil 55.3 mg film-coated tablets SPC no longer supplied (L01EA02 dasatinib)	–
Uxil 63.2 mg film-coated tablets no longer supplied (L01EA02 dasatinib)	–

Other groups of the same level

L01EB Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors 40 medicines
L01EC B-Raf serine-threonine kinase (BRAF) inhibitors 6 medicines
L01ED Anaplastic lymphoma kinase (ALK) inhibitors 14 medicines
L01EE Mitogen-activated protein kinase (MEK) inhibitors 10 medicines
L01EF Cyclin-dependent kinase (CDK) inhibitors 13 medicines
L01EG Mammalian target of rapamycin (mTOR) kinase inhibitors 27 medicines
L01EH Human epidermal growth factor receptor 2 (HER2) tyrosine kinase inhibitors 4 medicines
L01EJ Janus-associated kinase (JAK) inhibitors 18 medicines
L01EK Vascular endothelial growth factor receptor (VEGFR) tyrosine kinase inhibitors 12 medicines
L01EL Bruton's tyrosine kinase (BTK) inhibitors 8 medicines
L01EM Phosphatidylinositol-3-kinase (Pi3K) inhibitors 6 medicines
L01EX Other protein kinase inhibitors 94 medicines

Other names of the ATC group

German: L01EA BCR-ABL-Tyrosinkinase-Inhibitoren
German: L01EA BCR-ABL-Tyrosinkinase-Inhibitoren
Italian: L01EA Inibitori della trosin chinasi BCR-ABL
Turkish: L01EA BCR-ABL tirozin kinaz inhibitörleri
Czech: L01EA Tyrosinkinázové inhibitory BCR-ABL

Sources

Patient leaflets and SPCs: the MHRA product information (products.mhra.gov.uk) and the European Medicines Agency (EMA)
Active substances, ATC codes and legal categories: the NHS Dictionary of Medicines and Devices (dm+d), NHS Business Services Authority
World Health Organization (WHO): ATC/DDD classification, group L01EA

Contains public sector information licensed under the Open Government Licence v3.0.

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