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L01ED Anaplastic lymphoma kinase (ALK) inhibitors

ATC group of level 4 – chemical subgroup · in plain English: targeted cancer medicines (kinase inhibitors)

This site has the patient leaflet or the SPC of 14 medicines in this group and its subgroups.

Place in the ATC classification

  1. L Antineoplastic and immunomodulating agents 1,791 medicines
    1. L01 Antineoplastic agents 1,025 medicines
      1. L01E Protein kinase inhibitors, antineoplastic and immunomodulating agents 353 medicines
        1. L01ED Anaplastic lymphoma kinase (ALK) inhibitors 14 medicines
          1. L01ED01 crizotinib 5 medicines
          2. L01ED02 ceritinib 2 medicines
          3. L01ED03 alectinib 1 medicine
          4. L01ED04 brigatinib 4 medicines
          5. L01ED05 lorlatinib 2 medicines

Active substances in the group

Medicines in the group and its subgroups

MedicineLegal category
Alecensa 150 mg hard capsules SPC (L01ED03 alectinib) Prescription only (POM)
Alunbrig 180 mg film-coated tablets SPC (L01ED04 brigatinib) Prescription only (POM)
Alunbrig 30 mg film-coated tablets SPC (L01ED04 brigatinib) Prescription only (POM)
Alunbrig 90 mg film-coated tablets SPC (L01ED04 brigatinib) Prescription only (POM)
Alunbrig treatment Initiation Pack (90 mg film-coated tablets + 180 mg film-coated tablets) (L01ED04 brigatinib) Prescription only (POM)
Lorviqua 100 mg film-coated tablets SPC (L01ED05 lorlatinib) Prescription only (POM)
Lorviqua 25 mg film-coated tablets SPC (L01ED05 lorlatinib) Prescription only (POM)
Xalkori 150 mg granules in capsules for Opening SPC (L01ED01 crizotinib) Prescription only (POM)
Xalkori 20 mg granules in capsules for Opening SPC (L01ED01 crizotinib) Prescription only (POM)
Xalkori 200 mg hard capsules SPC (L01ED01 crizotinib) Prescription only (POM)
Xalkori 250 mg hard capsules SPC (L01ED01 crizotinib) Prescription only (POM)
Xalkori 50 mg granules in capsules for Opening (L01ED01 crizotinib) Prescription only (POM)
Zykadia 150 mg film-coated tablets SPC (L01ED02 ceritinib) Prescription only (POM)
Zykadia 150 mg hard capsules SPC no longer supplied (L01ED02 ceritinib) –

Other groups of the same level

Other names of the ATC group

Sources

  • Patient leaflets and SPCs: the MHRA product information (products.mhra.gov.uk) and the European Medicines Agency (EMA)
  • Active substances, ATC codes and legal categories: the NHS Dictionary of Medicines and Devices (dm+d), NHS Business Services Authority
  • World Health Organization (WHO): ATC/DDD classification, group L01ED

Contains public sector information licensed under the Open Government Licence v3.0.

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