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B02B Vitamin K and other hemostatics

ATC group of level 3 – pharmacological subgroup · in plain English: medicines to stop bleeding

This site has the patient leaflet or the SPC of 180 medicines in this group and its subgroups.

Place in the ATC classification

  1. B Blood and blood forming organ drugs 1,013 medicines
    1. B02 Antihemorrhagics 196 medicines
      1. B02B Vitamin K and other hemostatics 180 medicines
        1. B02BA Vitamin K containing hemostatics 6 medicines
        2. B02BB Fibrinogen containing hemostatics 3 medicines
        3. B02BC Local hemostatics 7 medicines
        4. B02BD Blood coagulation factors 136 medicines
        5. B02BX Other systemic hemostatics 28 medicines

Medicines in the group and its subgroups

MedicineLegal category
Konakion mm paediatric 2 mg / 0.2 ml solution for injection, Phytomenadione 2 mg / 0.2 ml solution for injection SPC (B02BA01 phytomenadione) –
Kovaltry 500 IU powder and solvent for solution for injection SPC (B02BD02 coagulation factor VIII) –
Menadiol Diphosphate 10 mg tablets SPC (B02BA02 menadione) Pharmacy medicine (P)
Mulpleo (previously Lusutrombopag Shionogi) SPC (B02BX Other systemic hemostatics) –
Mulpleo 3 mg film-coated tablets SPC no longer supplied (B02BX07 lusutrombopag) –
Neokay 1 mg capsules SPC no longer supplied (B02BA01 phytomenadione) –
Nonafact SPC (B02BD04 coagulation factor IX) –
Novoeight 1000 IU powder and solvent for solution for injection SPC no longer supplied (B02BD02 coagulation factor VIII) –
Novoeight 1500 IU powder and solvent for solution for injection SPC no longer supplied (B02BD02 coagulation factor VIII) –
Novoeight 2000 IU powder and solvent for solution for injection SPC no longer supplied (B02BD02 coagulation factor VIII) –
Novoeight 250 IU powder and solvent for solution for injection SPC no longer supplied (B02BD02 coagulation factor VIII) –
Novoeight 3000 IU powder and solvent for solution for injection SPC no longer supplied (B02BD02 coagulation factor VIII) –
Novoeight 500 IU powder and solvent for solution for injection SPC no longer supplied (B02BD02 coagulation factor VIII) –
Novoseven 1 mg (50 Kiu) powder and solvent for solution for injection (B02BD08 coagulation factor VIIa) Prescription only (POM)
Novoseven 2 mg (100 Kiu) powder and solvent for solution for injection SPC (B02BD08 coagulation factor VIIa) Prescription only (POM)
Novoseven 5 mg (250 Kiu) powder and solvent for solution for injection (B02BD08 coagulation factor VIIa) Prescription only (POM)
Novoseven 8 mg (400 Kiu) powder and solvent for solution for injection SPC (B02BD08 coagulation factor VIIa) Prescription only (POM)
Novothirteen 2500 IU powder and solvent for solution for injection (B02BD11 catridecacog) Prescription only (POM)
Nplate 125 micrograms powder for solution for injection SPC (B02BX04 romiplostim) Prescription only (POM)
Nplate 250 micrograms powder and solvent for solution for injection SPC (B02BX04 romiplostim) –
Nplate 250 micrograms powder for solution for injection SPC (B02BX04 romiplostim) Prescription only (POM)
Nplate 500 micrograms powder for solution for injection SPC (B02BX04 romiplostim) Prescription only (POM)
Nuwiq 1000 IU powder and solvent for solution for injection SPC (B02BD02 coagulation factor VIII) Prescription only (POM)
Nuwiq 1500 IU powder and solvent for solution for injection SPC (B02BD02 coagulation factor VIII) Prescription only (POM)
Nuwiq 2000 IU powder and solvent for solution for injection SPC (B02BD02 coagulation factor VIII) Prescription only (POM)
Nuwiq 250 IU powder and solvent for solution for injection SPC (B02BD02 coagulation factor VIII) Prescription only (POM)
Nuwiq 2500 IU powder and solvent for solution for injection SPC (B02BD02 coagulation factor VIII) Prescription only (POM)
Nuwiq 3000 IU powder and solvent for solution for injection SPC no longer supplied (B02BD02 coagulation factor VIII) –
Nuwiq 4000 IU powder and solvent for solution for injection (B02BD02 coagulation factor VIII) Prescription only (POM)
Nuwiq 500 IU powder and solvent for solution for injection SPC (B02BD02 coagulation factor VIII) Prescription only (POM)
Obizur 500 U/ml powder and solvent for solution for injection SPC (B02BD14 susoctocog alfa) Prescription only (POM)
Octanate LV 200 IU/ml powder and solvent for solution for injection SPC (B02BD06 von Willebrand factor and coagulation factor VIII in combination) Prescription only (POM)
Octaplex 1000 IU powder and solvent for solution for injection SPC (B02BD01 coagulation factor IX, II, VII and X in combination) Prescription only (POM)
Octaplex 500 IU powder and solvent for suspension for injection SPC (B02BD01 coagulation factor IX, II, VII and X in combination) Prescription only (POM)
Optivate 100 IU/ml A powder for solution for injection SPC (B02BD02 coagulation factor VIII) Prescription only (POM)
Optivate 250 IU 500 IU 1000 IU powder and solvent for solution for injection SPC (B02BD02 coagulation factor VIII) Prescription only (POM)
Prothromplex Total 1500 IU powder and solvent for solution for injection SPC (B02BD01 coagulation factor IX, II, VII and X in combination) Prescription only (POM)
Prothromplex Total 500 IU powder and solvent for solution for injection SPC (B02BD01 coagulation factor IX, II, VII and X in combination) Prescription only (POM)
Prothromplex Total 600 IU powder and solvent for solution for injection SPC no longer supplied (B02BD01 coagulation factor IX, II, VII and X in combination) –
Raplixa SPC (B02BC30 Local hemostatic combinations) –
Refacto AF 1000 IU powder and solvent for solution for injection SPC (B02BD02 coagulation factor VIII) –
Refacto AF 1000 IU powder and solvent for solution for injection in Pre-filled syringe SPC (B02BD02 coagulation factor VIII) Prescription only (POM)
Refacto AF 2000 IU powder and solvent for solution for injection SPC (B02BD02 coagulation factor VIII) –
Refacto AF 2000 IU powder and solvent for solution for injection in Pre-filled syringe SPC (B02BD02 coagulation factor VIII) Prescription only (POM)
Refacto AF 250 IU powder and solvent for solution for injection SPC (B02BD02 coagulation factor VIII) –
Refacto AF 250 IU powder and solvent for solution for injection in Pre-filled syringe SPC (B02BD02 coagulation factor VIII) Prescription only (POM)
Refacto AF 3000 IU powder and solvent for solution for injection in Pre-filled syringe SPC (B02BD02 coagulation factor VIII) Prescription only (POM)
Refacto AF 500 IU powder and solvent for solution for injection SPC (B02BD02 coagulation factor VIII) –
Refacto AF 500 IU powder and solvent for solution for injection in Pre-filled syringe SPC (B02BD02 coagulation factor VIII) Prescription only (POM)
Refixia SPC (B02BD04 coagulation factor IX) Prescription only (POM)
Refixia 1000 IU powder and solvent for solution for injection SPC (B02BD04 coagulation factor IX) Prescription only (POM)
Refixia 2000 IU powder and solvent for solution for injection SPC (B02BD04 coagulation factor IX) Prescription only (POM)
Refixia 500 IU powder and solvent for solution for injection SPC (B02BD04 coagulation factor IX) Prescription only (POM)
Replenine-vf 50 IU/ml Human Factor IX A powder for solution SPC (B02BD04 coagulation factor IX) Prescription only (POM)
Revolade 12.5 mg film-coated tablets SPC (B02BX05 eltrombopag) Prescription only (POM)
Revolade 25 mg film-coated tablets SPC (B02BX05 eltrombopag) Prescription only (POM)
Revolade 25 mg powder for oral suspension SPC (B02BX05 eltrombopag) Prescription only (POM)
Revolade 50 mg film-coated tablets SPC (B02BX05 eltrombopag) Prescription only (POM)
Revolade 75 mg film-coated tablets SPC (B02BX05 eltrombopag) Prescription only (POM)
Riastap 1 g powder for solution for injection or infusion SPC (B02BB01 fibrinogen, human) Prescription only (POM)
Rixubis 1000 IU powder for solution for injection SPC (B02BD04 coagulation factor IX) Prescription only (POM)
Rixubis 2000 IU powder for solution for injection SPC (B02BD04 coagulation factor IX) Prescription only (POM)
Rixubis 250 IU powder for solution for injection SPC no longer supplied (B02BD04 coagulation factor IX) –
Rixubis 3000 IU powder for solution for injection SPC no longer supplied (B02BD04 coagulation factor IX) –
Rixubis 500 IU powder for solution for injection SPC no longer supplied (B02BD04 coagulation factor IX) –
Tachosil Sealant Matrix SPC (B02BC30 Local hemostatic combinations) –
Tavlesse 100 mg film-coated tablets SPC (B02BX Other systemic hemostatics) Prescription only (POM)
Tavlesse 150 mg film-coated tablets SPC (B02BX09 fostamatinib) Prescription only (POM)
VeraSeal SPC (B02BC Local hemostatics) Prescription only (POM)
Veraseal Solutions for Sealant SPC (B02BC Local hemostatics) –
Veyvondi 1300 IU powder and solvent for solution for injection SPC (B02BD10 von Willebrand factor) Prescription only (POM)
Veyvondi 650 IU powder and solvent for solution for injection SPC (B02BD10 von Willebrand factor) Prescription only (POM)
Vihuma SPC (B02BD02 coagulation factor VIII) –
Voncento 1000 IU Fviii/2400 IU VWF (10 ml solvent) powder and solvent for solution for injection (B02BD06 von Willebrand factor and coagulation factor VIII in combination) Prescription only (POM)
Voncento 250 IU Fviii / 600 IU VWF (5 ml solvent) powder and solvent for solution for injection (B02BD06 von Willebrand factor and coagulation factor VIII in combination) Prescription only (POM)
Voncento 500 IU Fviii / 1200 IU VWF (10 ml solvent) powder and solvent for solution for injection (B02BD06 von Willebrand factor and coagulation factor VIII in combination) Prescription only (POM)
Voncento 500 IU Fviii /1200 IU VWF (5 ml solvent) powder and solvent for solution for injection (B02BD06 von Willebrand factor and coagulation factor VIII in combination) Prescription only (POM)
Willfact 1000 IU powder and solvent for solution for injection SPC (B02BD10 von Willebrand factor) Prescription only (POM)
Willfact 2000 I.U powder and solvent for solution for injection SPC (B02BD10 von Willebrand factor) Prescription only (POM)
Willfact 500 I.U powder and solvent for solution for injection SPC (B02BD10 von Willebrand factor) Prescription only (POM)

Sources

  • Patient leaflets and SPCs: the MHRA product information (products.mhra.gov.uk) and the European Medicines Agency (EMA)
  • Active substances, ATC codes and legal categories: the NHS Dictionary of Medicines and Devices (dm+d), NHS Business Services Authority
  • World Health Organization (WHO): ATC/DDD classification, group B02B

Contains public sector information licensed under the Open Government Licence v3.0.

Ask your doctor or pharmacist which medicine is right for you.