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L04AA Selective immunosuppressants

ATC group of level 4 – chemical subgroup · in plain English: medicines suppressing the immune system, e.g. after a transplant or for autoimmune diseases

This site has the patient leaflet or the SPC of 115 medicines in this group and its subgroups.

Place in the ATC classification

How to read ATC codes – what the levels mean and what a code does not tell you.

  1. L Antineoplastic and immunomodulating agents 1,791 medicines
    1. L04 Immunosuppressants 545 medicines
      1. L04A Immunosuppressants 543 medicines
        1. L04AA Selective immunosuppressants 115 medicines
          1. L04AA03 antilymphocyte immunoglobulin (horse) 1 medicine
          2. L04AA04 antithymocyte immunoglobulin (rabbit) 1 medicine
          3. L04AA06 mycophenolic acid 26 medicines
          4. L04AA10 sirolimus 4 medicines
          5. L04AA13 leflunomide 18 medicines
          6. L04AA18 everolimus 3 medicines
          7. L04AA21 efalizumab 1 medicine
          8. L04AA23 natalizumab 2 medicines
          9. L04AA24 abatacept 5 medicines
          10. L04AA25 eculizumab 1 medicine
          11. L04AA26 belimumab 3 medicines
          12. L04AA27 fingolimod 12 medicines
          13. L04AA28 belatacept 1 medicine
          14. L04AA29 tofacitinib 3 medicines
          15. L04AA31 teriflunomide 1 medicine
          16. L04AA32 apremilast 10 medicines
          17. L04AA33 vedolizumab 3 medicines
          18. L04AA34 alemtuzumab 2 medicines
          19. L04AA36 ocrelizumab 1 medicine
          20. L04AA37 baricitinib 1 medicine
          21. L04AA38 ozanimod 3 medicines
          22. L04AA40 cladribine 2 medicines
          23. L04AA41 imlifidase 1 medicine
          24. L04AA42 siponimod 2 medicines
          25. L04AA43 ravulizumab 2 medicines
          26. L04AA44 upadacitinib 2 medicines
          27. L04AA45 filgotinib 2 medicines

8 more subgroups have no medicine with a leaflet on this site.

Active substances in the group

Medicines in the group and its subgroups

MedicineLegal category
Aderolio 250 mcg tablets SPC (L04AA18 everolimus) –
Aderolio 500 mcg tablets SPC (L04AA18 everolimus) –
Apremilast 10 mg + 20 mg + 30 mg film-coated tablets, treatment Initiation Pack SPC (L04AA32 apremilast) Prescription only (POM)
Apremilast 10 mg, 20 mg, 30 mg film-coated tablets SPC (L04AA32 apremilast) Prescription only (POM)
Apremilast 10 mg/20 mg/30 mg film-coated tablets treatment Initiation Pack SPC (L04AA32 apremilast) Prescription only (POM)
Apremilast 30 mg film-coated tablets SPC (L04AA32 apremilast) Prescription only (POM)
Apremilast Krka 30 mg film-coated tablets SPC (L04AA32 apremilast) Prescription only (POM)
Apremilast Zentiva 30 mg film-coated tablets (L04AA32 apremilast) Prescription only (POM)
Arava 20 mg film-coated tablets SPC no longer supplied (L04AA13 leflunomide) –
Atgam 50 mg / ml concentrate for solution for infusion SPC (L04AA03 antilymphocyte immunoglobulin (horse)) Prescription only (POM)
Aubagio 7 mg film-coated tablets SPC no longer supplied (L04AA31 teriflunomide) –
Benlysta SPC (L04AA26 belimumab) Prescription only (POM)
Benlysta 200 mg solution for injection in Pre-filled syringe., Benlysta 200 mg solution for injection in Pre-filled pen SPC (L04AA26 belimumab) Prescription only (POM)
Benlysta 400 mg powder for concentrate for solution for infusion SPC (L04AA26 belimumab) Prescription only (POM)
Cellcept 1 g/5 ml powder for oral suspension SPC (L04AA06 mycophenolic acid) Prescription only (POM)
Cellcept 250 mg capsule-hard SPC (L04AA06 mycophenolic acid) Prescription only (POM)
Cellcept 500 mg film-coated tablets SPC (L04AA06 mycophenolic acid) Prescription only (POM)
Cellcept 500 mg powder for concentrate for solution for infusion SPC (L04AA06 mycophenolic acid) Prescription only (POM)
Ceptava 180 mg gastro-resistant tablets SPC (L04AA06 mycophenolic acid) Prescription only (POM)
Ceptava 360 mg gastro-resistant tablets SPC (L04AA06 mycophenolic acid) Prescription only (POM)
Certican 0.25 mg tablets SPC (L04AA18 everolimus) Prescription only (POM)
Cladribine 10 mg tablets SPC (L04AA40 cladribine) Prescription only (POM)
Entyvio 108 mg solution for injection in Pre Filled pen SPC Prescription only (POM)
Entyvio 108 mg solution for injection in Pre Filled syringe SPC (L04AA33 vedolizumab) Prescription only (POM)
Entyvio 300 mg powder for concentrate for solution for infusion SPC (L04AA33 vedolizumab) Prescription only (POM)
Fingolimod 0.5 mg hard capsules SPC (L04AA27 fingolimod) Prescription only (POM)
Fingolimod Accord 0.5 mg hard capsules (L04AA27 fingolimod) Prescription only (POM)
Fingolimod Aristo 0.5 mg hard capsules SPC (L04AA27 fingolimod) Prescription only (POM)
Fingolimod Fresenius Kabi 0.5 mg hard capsules SPC (L04AA27 fingolimod) Prescription only (POM)
Fingolimod Hydrochloride Sandoz 0.5 mg hard capsules SPC (L04AA27 fingolimod) Prescription only (POM)
Fingolimod Krka 0.5 mg hard capsules SPC (L04AA27 fingolimod) Prescription only (POM)
Fingolimod Mylan SPC (L04AA27 fingolimod) –
Fingolimod Sun 0.5 mg hard capsules SPC (L04AA27 fingolimod) Prescription only (POM)
Fingolimod Teva 0.5 mg capsule hard SPC (L04AA27 fingolimod) Prescription only (POM)
Fingolimod Zentiva 0.5 mg hard capsules SPC (L04AA27 fingolimod) Prescription only (POM)
Gilenya 0.5 mg hard capsules SPC (L04AA27 fingolimod) Prescription only (POM)
Idefirix 11 mg powder for concentrate for solution for infusion SPC Prescription only (POM)
Inzolfi 0.5 mg hard capsules SPC (L04AA27 fingolimod) –
Jyseleca 100 mg film-coated tablets SPC (L04AA45 filgotinib) Prescription only (POM)
Jyseleca 200 mg film-coated tablets SPC Prescription only (POM)
Leflunomide 10 mg film-coated tablets SPC (L04AA13 leflunomide) Prescription only (POM)
Leflunomide 10 mg tablets SPC (L04AA13 leflunomide) Prescription only (POM)
Leflunomide 100 mg film-coated tablets SPC not available (L04AA13 leflunomide) –
Leflunomide 100 mg tablets SPC not available (L04AA13 leflunomide) –
Leflunomide 20 mg film-coated tablets SPC (L04AA13 leflunomide) Prescription only (POM)
Leflunomide medac SPC (L04AA13 leflunomide) –
Leflunomide Medac 15 mg film-coated tablets SPC (L04AA13 leflunomide) Prescription only (POM)
Leflunomide Medac 20 mg film-coated tablets SPC (L04AA13 leflunomide) Prescription only (POM)
Leflunomide Mylan 20 mg film-coated tablets SPC (L04AA13 leflunomide) Prescription only (POM)
Leflunomide ratiopharm SPC (L04AA13 leflunomide) –
Leflunomide Teva SPC (L04AA13 leflunomide) –
Leflunomide Tillomed 10 mg tablets SPC (L04AA13 leflunomide) Prescription only (POM)
Leflunomide Tillomed 20 mg tablets SPC (L04AA13 leflunomide) Prescription only (POM)
Leflunomide Zentiva (previously Leflunomide Winthrop) SPC (L04AA13 leflunomide) –
Leflunomide Zentiva 100 mg film-coated tablets SPC not available (L04AA13 leflunomide) –
Leflunomide Zentiva 20 mg film-coated tablets SPC (L04AA13 leflunomide) Prescription only (POM)
Lemtrada SPC (L04AA34 alemtuzumab) Prescription only (POM)
Lemtrada 12 mg concentrate for solution for infusion SPC (L04AA34 alemtuzumab) Prescription only (POM)
Mavenclad 10 mg tablets SPC (L04AA40 cladribine) Prescription only (POM)
Mayzent 0.25 mg film-coated tablets SPC (L04AA42 siponimod) Prescription only (POM)
Mayzent 2 mg film-coated tablets SPC (L04AA42 siponimod) Prescription only (POM)
Myclausen SPC (L04AA06 mycophenolic acid) –
Mycophenolate Mofetil 1 g/5 ml oral suspension SPC (L04AA06 mycophenolic acid) Prescription only (POM)
Mycophenolate Mofetil 1 g/5 ml powder for oral suspension SPC (L04AA06 mycophenolic acid) Prescription only (POM)
Mycophenolate Mofetil 250 mg capsules (L04AA06 mycophenolic acid) Prescription only (POM)
Mycophenolate Mofetil 500 mg film-coated tablets SPC (L04AA06 mycophenolic acid) Prescription only (POM)
Mycophenolate Mofetil 500 mg powder for concentrate for solution for infusion SPC no longer supplied (L04AA06 mycophenolic acid) –
Mycophenolate Mofetil Ascend 1 g /5 ml powder for oral suspension (L04AA06 mycophenolic acid) Prescription only (POM)
Mycophenolate Mofetil Mylan 500 mg film-coated tablets SPC no longer supplied (L04AA06 mycophenolic acid) –
Mycophenolate Mofetil Sandoz 250 mg capsules hard SPC no longer supplied (L04AA06 mycophenolic acid) –
Mycophenolate Mofetil Sandoz 500 mg film-coated tablets SPC no longer supplied (L04AA06 mycophenolic acid) –
Mycophenolate mofetil Teva SPC (L04AA06 mycophenolic acid) –
Mycophenolate Mofetil Teva 500 mg film-coated tablets SPC (L04AA06 mycophenolic acid) Prescription only (POM)
Mycophenolate Mofetil Tillomed 250 mg capsules SPC (L04AA06 mycophenolic acid) Prescription only (POM)
Mycophenolate Mofetil Tillomed 500 mg film-coated tablets SPC (L04AA06 mycophenolic acid) Prescription only (POM)
Mycophenolic Acid 180 mg gastro-resistant tablets SPC (L04AA06 mycophenolic acid) Prescription only (POM)
Mycophenolic Acid 360 mg gastro-resistant tablets SPC (L04AA06 mycophenolic acid) Prescription only (POM)
Myfenax 250 mg hard capsules SPC (L04AA06 mycophenolic acid) Prescription only (POM)
Myfenax 500 mg film-coated tablets SPC (L04AA06 mycophenolic acid) Prescription only (POM)
Myfortic 180 mg film-coated gastro-resistant tablets SPC (L04AA06 mycophenolic acid) Prescription only (POM)
Myfortic 360 mg film-coated gastro-resistant tablets SPC (L04AA06 mycophenolic acid) Prescription only (POM)
Nulojix 250 mg powder for concentrate for solution for infusion (L04AA28 belatacept) Prescription only (POM)
Ocrevus 300 mg concentrate for solution for infusion SPC Prescription only (POM)
Olumiant 4 mg film-coated tablets SPC (L04AA37 baricitinib) Prescription only (POM)
Orencia 125 mg solution for injection in Pre-filled pen SPC (L04AA24 abatacept) Prescription only (POM)
Orencia 125 mg solution for injection in Pre-filled syringe SPC (L04AA24 abatacept) Prescription only (POM)
Orencia 250 mg powder for concentrate for solution for infusion SPC (L04AA24 abatacept) Prescription only (POM)
Orencia 50 mg solution for injection in Pre-filled syringe SPC (L04AA24 abatacept) Prescription only (POM)
Orencia 87.5 mg solution for injection in Pre-filled syringe SPC (L04AA24 abatacept) Prescription only (POM)
Otezla SPC (L04AA32 apremilast) Prescription only (POM)
Otezla 20 mg film-coated tablets, Otezla 10 mg film-coated tablets SPC (L04AA32 apremilast) Prescription only (POM)
Otezla 30 mg film-coated tablets (L04AA32 apremilast) Prescription only (POM)
Ponvory 2 mg 3 mg 4 mg 5 mg 6 mg 7 mg 8 mg 9 mg 10 mg film-coated tablets SPC Prescription only (POM)
Rapamune SPC (L04AA10 sirolimus) Prescription only (POM)
Rapamune 0.5 mg coated tablets SPC (L04AA10 sirolimus) Prescription only (POM)
Rapamune 1 mg / ml oral solution SPC (L04AA10 sirolimus) Prescription only (POM)
Rapamune 2 mg coated tablets SPC (L04AA10 sirolimus) Prescription only (POM)
Raptiva SPC (L04AA21 efalizumab) –
Repso SPC (L04AA13 leflunomide) –
Rinvoq 15 mg prolonged-release tablets SPC Prescription only (POM)

Other groups of the same level

Other names of the ATC group

Sources

  • Patient leaflets and SPCs: the MHRA product information (products.mhra.gov.uk) and the European Medicines Agency (EMA)
  • Active substances, ATC codes and legal categories: the NHS Dictionary of Medicines and Devices (dm+d), NHS Business Services Authority
  • World Health Organization (WHO): ATC/DDD classification, group L04AA

Contains public sector information licensed under the Open Government Licence v3.0.

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