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L04AA Selective immunosuppressants

ATC group of level 4 – chemical subgroup · in plain English: medicines suppressing the immune system, e.g. after a transplant or for autoimmune diseases

This site has the patient leaflet or the SPC of 115 medicines in this group and its subgroups.

Place in the ATC classification

How to read ATC codes – what the levels mean and what a code does not tell you.

  1. L Antineoplastic and immunomodulating agents 1,791 medicines
    1. L04 Immunosuppressants 545 medicines
      1. L04A Immunosuppressants 543 medicines
        1. L04AA Selective immunosuppressants 115 medicines
          1. L04AA03 antilymphocyte immunoglobulin (horse) 1 medicine
          2. L04AA04 antithymocyte immunoglobulin (rabbit) 1 medicine
          3. L04AA06 mycophenolic acid 26 medicines
          4. L04AA10 sirolimus 4 medicines
          5. L04AA13 leflunomide 18 medicines
          6. L04AA18 everolimus 3 medicines
          7. L04AA21 efalizumab 1 medicine
          8. L04AA23 natalizumab 2 medicines
          9. L04AA24 abatacept 5 medicines
          10. L04AA25 eculizumab 1 medicine
          11. L04AA26 belimumab 3 medicines
          12. L04AA27 fingolimod 12 medicines
          13. L04AA28 belatacept 1 medicine
          14. L04AA29 tofacitinib 3 medicines
          15. L04AA31 teriflunomide 1 medicine
          16. L04AA32 apremilast 10 medicines
          17. L04AA33 vedolizumab 3 medicines
          18. L04AA34 alemtuzumab 2 medicines
          19. L04AA36 ocrelizumab 1 medicine
          20. L04AA37 baricitinib 1 medicine
          21. L04AA38 ozanimod 3 medicines
          22. L04AA40 cladribine 2 medicines
          23. L04AA41 imlifidase 1 medicine
          24. L04AA42 siponimod 2 medicines
          25. L04AA43 ravulizumab 2 medicines
          26. L04AA44 upadacitinib 2 medicines
          27. L04AA45 filgotinib 2 medicines

8 more subgroups have no medicine with a leaflet on this site.

Medicines in the group and its subgroups

MedicineLegal category
Rinvoq 30 mg prolonged-release tablets SPC (L04AA44 upadacitinib) Prescription only (POM)
Saphnelo 300 mg concentrate for solution for infusion SPC –
Soliris 300 mg concentrate for solution for infusion SPC (L04AA25 eculizumab) Prescription only (POM)
Thymoglobuline 25 mg powder for solution for infusion SPC (L04AA04 antithymocyte immunoglobulin (rabbit)) Prescription only (POM)
Treatment Initiation Pack -, Apremilast 10 mg + 20 mg + 30 mg film-coated tablets SPC (L04AA32 apremilast) –
Tysabri 150 mg solution for injection in Pre-filled syringe SPC (L04AA23 natalizumab) Prescription only (POM)
Tysabri 300 mg concentrate for solution for infusion SPC (L04AA23 natalizumab) Prescription only (POM)
Ultomiris SPC (L04AA43 ravulizumab) Prescription only (POM)
Ultomiris 10 mg / ml concentrate for solution for infusion SPC no longer supplied (L04AA43 ravulizumab) –
Xeljanz 1 mg / ml oral solution SPC (L04AA29 tofacitinib) Prescription only (POM)
Xeljanz 10 mg film-coated tablets SPC (L04AA29 tofacitinib) Prescription only (POM)
Xeljanz 11 mg prolonged-release tablets SPC (L04AA29 tofacitinib) Prescription only (POM)
Zeposia SPC (L04AA38 ozanimod) Prescription only (POM)
Zeposia 0.23 mg / 0.46 mg hard capsules SPC (L04AA38 ozanimod) Prescription only (POM)
Zeposia 0.92 mg hard capsules SPC (L04AA38 ozanimod) Prescription only (POM)

Sources

  • Patient leaflets and SPCs: the MHRA product information (products.mhra.gov.uk) and the European Medicines Agency (EMA)
  • Active substances, ATC codes and legal categories: the NHS Dictionary of Medicines and Devices (dm+d), NHS Business Services Authority
  • World Health Organization (WHO): ATC/DDD classification, group L04AA

Contains public sector information licensed under the Open Government Licence v3.0.

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