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L04AB Tumor necrosis factor alpha (TNF-alpha) inhibitors

ATC group of level 4 – chemical subgroup · in plain English: medicines suppressing the immune system, e.g. after a transplant or for autoimmune diseases

This site has the patient leaflet or the SPC of 75 medicines in this group and its subgroups.

Place in the ATC classification

  1. L Antineoplastic and immunomodulating agents 1,791 medicines
    1. L04 Immunosuppressants 545 medicines
      1. L04A Immunosuppressants 543 medicines
        1. L04AB Tumor necrosis factor alpha (TNF-alpha) inhibitors 75 medicines
          1. L04AB01 etanercept 15 medicines
          2. L04AB02 infliximab 7 medicines
          3. L04AB04 adalimumab 42 medicines
          4. L04AB05 certolizumab pegol 3 medicines
          5. L04AB06 golimumab 8 medicines

2 more subgroups have no medicine with a leaflet on this site.

Active substances in the group

Medicines in the group and its subgroups

MedicineLegal category
A Mgevita 20 mg solution for injection in Pre-filled syringe no longer supplied (L04AB04 adalimumab) –
A Mgevita 40 mg solution for injection in Pre-filled pen no longer supplied (L04AB04 adalimumab) –
Amgevita HCF 20 mg solution for injection in Pre-filled syringe (L04AB04 adalimumab) Prescription only (POM)
Amgevita HCF 40 mg solution for injection in Pre-filled pen SPC (L04AB04 adalimumab) Prescription only (POM)
Amgevita HCF 40 mg solution for injection in Pre-filled syringe (L04AB04 adalimumab) Prescription only (POM)
Amgevita HCF 80 mg solution for injection in Pre-filled pen SPC (L04AB04 adalimumab) Prescription only (POM)
Amgevita HCF 80 mg solution for injection in Pre-filled syringe SPC (L04AB04 adalimumab) Prescription only (POM)
Amsparity SPC (L04AB04 adalimumab) –
Amsparity 20 mg solution for injection in Pre Filled syringe SPC (L04AB04 adalimumab) –
Benepali 25 mg solution for injection in Pre-filled syringe SPC (L04AB01 etanercept) Prescription only (POM)
Benepali 50 mg solution for injection in Pre-filled pen SPC (L04AB01 etanercept) Prescription only (POM)
Benepali 50 mg solution for injection in Pre-filled syringe SPC (L04AB01 etanercept) Prescription only (POM)
Cimzia 200 mg solution for injection in dose-dispenser cartridge SPC no longer supplied (L04AB05 certolizumab pegol) –
Cimzia 200 mg solution for injection in Pre-filled pen SPC (L04AB05 certolizumab pegol) Prescription only (POM)
Cimzia 200 mg solution for injection in Pre-filled syringe SPC (L04AB05 certolizumab pegol) Prescription only (POM)
Cyltezo SPC (L04AB04 adalimumab) –
Enbrel 10 mg powder and solvent for solution for injection for paediatric use SPC (L04AB01 etanercept) Prescription only (POM)
Enbrel 25 mg powder and solvent for solution for injection SPC (L04AB01 etanercept) –
Enbrel 25 mg solution for injection in Pre-filled pen SPC (L04AB01 etanercept) –
Enbrel 25 mg solution for injection in Pre-filled syringe, Enbrel 25 mg solution for injection in Pre-filled pen SPC (L04AB01 etanercept) Prescription only (POM)
Enbrel 50 mg solution for injection in Pre-filled pen SPC (L04AB01 etanercept) Prescription only (POM)
Enbrel 50 mg solution for injection in Pre-filled pen, Enbrel 50 mg solution for injection in Pre-filled syringe SPC (L04AB01 etanercept) Prescription only (POM)
Erelzi 25 mg solution for injection in Pre Filled syringe SPC (L04AB01 etanercept) Prescription only (POM)
Erelzi 50 mg solution for injection in Pre Filled pen SPC (L04AB01 etanercept) Prescription only (POM)
Flixabi SPC (L04AB02 infliximab) Prescription only (POM)
Flixabi 100 mg powder for concentrate for solution for infusion SPC (L04AB02 infliximab) Prescription only (POM)
Gobivaz 100 mg solution for injection in Pre-filled pen SPC (L04AB06 golimumab) Prescription only (POM)
Gobivaz 100 mg solution for injection in Pre-filled syringe SPC (L04AB06 golimumab) Prescription only (POM)
Gobivaz 50 mg solution for injection in Pre-filled pen SPC (L04AB06 golimumab) Prescription only (POM)
Gobivaz 50 mg solution for injection in Pre-filled syringe SPC (L04AB06 golimumab) Prescription only (POM)
Hefiya SPC (L04AB04 adalimumab) –
Hukyndra 40 mg solution for injection in Pre-filled syringe SPC (L04AB04 adalimumab) –
Hukyndra 80 mg solution for injection in Pre-filled syringe SPC (L04AB04 adalimumab) –
Hulio (Adalimumab) / 40 mg / solution for injection in prefilled pen (L04AB04 adalimumab) –
Hulio 20 mg solution for injection in Pre-filled syringe SPC no longer supplied (L04AB04 adalimumab) –
Hulio 40 mg / 0.8 ml solution for injection SPC no longer supplied (L04AB04 adalimumab) –
Hulio 40 mg solution for injection in Pre-filled syringe SPC no longer supplied (L04AB04 adalimumab) –
Humira 20 mg solution for injection in Pre-filled syringe SPC (L04AB04 adalimumab) Prescription only (POM)
Humira 40 mg solution for injection in Pre-filled syringe SPC (L04AB04 adalimumab) –
Humira 40 mg solution for injection in Pre-filled syringe, Humira 40 mg solution for injection in Pre-filled pen SPC (L04AB04 adalimumab) –
Humira 80 mg solution for injection in Pre-filled syringe no longer supplied (L04AB04 adalimumab) –
Hyrimoz 20 mg solution for injection in Pre-filled syringe SPC (L04AB04 adalimumab) Prescription only (POM)
Hyrimoz 20 mg/0.2 ml solution for injection in Pre-filled syringe SPC (L04AB04 adalimumab) Prescription only (POM)
Hyrimoz 40 mg solution for injection in Pre-filled syringe SPC (L04AB04 adalimumab) –
Hyrimoz 40 mg/0.4 ml solution for injection in Pre-filled pen SPC (L04AB04 adalimumab) Prescription only (POM)
Hyrimoz 40 mg/0.4 ml solution for injection in Pre-filled syringe SPC (L04AB04 adalimumab) Prescription only (POM)
Hyrimoz 80 mg/0.8 ml solution for injection in Pre-filled syringe SPC (L04AB04 adalimumab) Prescription only (POM)
Idacio 40 mg / 0.8 ml solution for injection for paediatric use SPC (L04AB04 adalimumab) Prescription only (POM)
Idacio 40 mg solution for injection in Pre-filled pen SPC (L04AB04 adalimumab) Prescription only (POM)
Idacio 40 mg solution for injection in Pre-filled syringe SPC (L04AB04 adalimumab) Prescription only (POM)
Imraldi SPC (L04AB04 adalimumab) Prescription only (POM)
Imraldi 40 mg / 0.8 ml solution for injection SPC (L04AB04 adalimumab) Prescription only (POM)
Imraldi 40 mg solution for injection in Pre-filled syringe SPC (L04AB04 adalimumab) –
Inflectra 100 mg powder for concentrate for solution for infusion SPC no longer supplied (L04AB02 infliximab) –
Kromeya SPC (L04AB04 adalimumab) –
Libmyris SPC (L04AB04 adalimumab) –
Lifmior SPC (L04AB01 etanercept) –
Nepexto 25 mg solution for injection in Pre-filled syringe SPC (L04AB01 etanercept) –
Nepexto 50 mg solution for injection in Pre-filled pen SPC (L04AB01 etanercept) –
Nepexto 50 mg solution for injection in Pre-filled syringe SPC (L04AB01 etanercept) –
Remicade 100 mg powder for concentrate for solution for infusion SPC (L04AB02 infliximab) Prescription only (POM)
Remsima 100 mg powder for concentrate for solution for infusion SPC (L04AB02 infliximab) –
Remsima 120 mg solution for injection in Pre-filled pen SPC (L04AB02 infliximab) Prescription only (POM)
Simponi 100 mg solution for injection in Pre-filled pen SPC (L04AB06 golimumab) Prescription only (POM)
Simponi 45 mg / 0.45 ml solution for injection in Pre-filled pen SPC (L04AB06 golimumab) Prescription only (POM)
Simponi 50 mg solution for injection in Pre-filled pen SPC (L04AB06 golimumab) Prescription only (POM)
Simponi 50 mg solution for injection in Pre-filled syringe SPC (L04AB06 golimumab) Prescription only (POM)
Solymbic SPC (L04AB04 adalimumab) –
Yuflyma SPC (L04AB04 adalimumab) Prescription only (POM)
Yuflyma 20 mg solution for injection in Pre-filled syringe SPC (L04AB04 adalimumab) Prescription only (POM)
Yuflyma 40 mg solution for injection in Pre-filled pen (L04AB04 adalimumab) Prescription only (POM)
Yuflyma 40 mg solution for injection in Pre-filled pen, Yuflyma 40 mg solution for injection in Pre-filled syringe SPC (L04AB04 adalimumab) Prescription only (POM)
Yuflyma 40 mg solution for injection in Pre-filled syringe SPC no longer supplied (L04AB04 adalimumab) –
Yuflyma 80 mg solution for injection in Pre-filled pen (L04AB04 adalimumab) Prescription only (POM)
Zessly 100 mg powder for concentrate for solution for infusion SPC (L04AB02 infliximab) Prescription only (POM)

Other groups of the same level

Other names of the ATC group

Sources

  • Patient leaflets and SPCs: the MHRA product information (products.mhra.gov.uk) and the European Medicines Agency (EMA)
  • Active substances, ATC codes and legal categories: the NHS Dictionary of Medicines and Devices (dm+d), NHS Business Services Authority
  • World Health Organization (WHO): ATC/DDD classification, group L04AB

Contains public sector information licensed under the Open Government Licence v3.0.

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