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L04A Immunosuppressants

ATC group of level 3 – pharmacological subgroup · in plain English: medicines suppressing the immune system, e.g. after a transplant or for autoimmune diseases

This site has the patient leaflet or the SPC of 543 medicines in this group and its subgroups.

Place in the ATC classification

  1. L Antineoplastic and immunomodulating agents 1,791 medicines
    1. L04 Immunosuppressants 545 medicines
      1. L04A Immunosuppressants 543 medicines
        1. L04AA Selective immunosuppressants 115 medicines
        2. L04AB Tumor necrosis factor alpha (TNF-alpha) inhibitors 75 medicines
        3. L04AC Interleukin inhibitors 78 medicines
        4. L04AD Calcineurin inhibitors 69 medicines
        5. L04AX Other immunosuppressants 206 medicines

Medicines in the group and its subgroups

MedicineLegal category
Pirfenidone 267 mg capsules hard SPC not available (L04AX05 pirfenidone) –
Pirfenidone 267 mg film-coated tablets SPC no longer supplied (L04AX05 pirfenidone) –
Pirfenidone 267 mg tablets SPC (L04AX05 pirfenidone) Prescription only (POM)
Pirfenidone 276 mg film-coated tablets SPC (L04AX05 pirfenidone) Prescription only (POM)
Pirfenidone 534 mg film-coated tablets SPC (L04AX05 pirfenidone) –
Pirfenidone 801 mg film-coated tablets SPC (L04AX05 pirfenidone) Prescription only (POM)
Pirfenidone 801 mg tablets SPC (L04AX05 pirfenidone) Prescription only (POM)
Pirfenidone Lupin 267 mg film-coated tablets SPC no longer supplied (L04AX05 pirfenidone) –
Pirfenidone Lupin 801 mg film-coated tablets SPC no longer supplied (L04AX05 pirfenidone) –
Pirfenidone, 534 mg tablets SPC (L04AX05 pirfenidone) –
Pomalidomide 1 mg capsule, hard SPC no longer supplied (L04AX06 pomalidomide) –
Pomalidomide 2 mg capsule, hard SPC no longer supplied (L04AX06 pomalidomide) –
Pomalidomide 3 mg hard capsules no longer supplied (L04AX06 pomalidomide) –
Pomalidomide 4 mg capsule, hard SPC no longer supplied (L04AX06 pomalidomide) –
Pomalidomide Zentiva 1 mg hard capsules SPC (L04AX06 pomalidomide) Prescription only (POM)
Pomalidomide Zentiva 4 mg hard capsules SPC (L04AX06 pomalidomide) Prescription only (POM)
Ponvory 2 mg 3 mg 4 mg 5 mg 6 mg 7 mg 8 mg 9 mg 10 mg film-coated tablets SPC (L04AA Selective immunosuppressants) Prescription only (POM)
Prograf 0.5 mg capsules (L04AD02 tacrolimus) Prescription only (POM)
Prograf 0.5 mg hard capsules (L04AD02 tacrolimus) Prescription only (POM)
Prograf 1 mg capsules (L04AD02 tacrolimus) Prescription only (POM)
Prograf 1 mg hard capsules (L04AD02 tacrolimus) Prescription only (POM)
Prograf 5 mg capsules (L04AD02 tacrolimus) Prescription only (POM)
Prograf concentrate for infusion 5 mg/ml SPC (L04AD02 tacrolimus) Prescription only (POM)
Prograf hard capsules 0.5 mg SPC (L04AD02 tacrolimus) Prescription only (POM)
Prograf hard capsules 1 mg SPC (L04AD02 tacrolimus) Prescription only (POM)
Prograf hard capsules 5 mg SPC (L04AD02 tacrolimus) Prescription only (POM)
Pyzchiva 90 mg solution for injection in Pre-filled syringe (L04AC05 ustekinumab) Prescription only (POM)
Rapamune SPC (L04AA10 sirolimus) Prescription only (POM)
Rapamune 0.5 mg coated tablets SPC (L04AA10 sirolimus) Prescription only (POM)
Rapamune 1 mg / ml oral solution SPC (L04AA10 sirolimus) Prescription only (POM)
Rapamune 2 mg coated tablets SPC (L04AA10 sirolimus) Prescription only (POM)
Raptiva SPC (L04AA21 efalizumab) –
Remicade 100 mg powder for concentrate for solution for infusion SPC (L04AB02 infliximab) Prescription only (POM)
Remsima 100 mg powder for concentrate for solution for infusion SPC (L04AB02 infliximab) –
Remsima 120 mg solution for injection in Pre-filled pen SPC (L04AB02 infliximab) Prescription only (POM)
Repso SPC (L04AA13 leflunomide) –
Revlimid 10 mg hard capsules SPC no longer supplied (L04AX04 lenalidomide) –
Revlimid 15 mg hard capsules SPC no longer supplied (L04AX04 lenalidomide) –
Revlimid 2.5 mg hard capsules SPC no longer supplied (L04AX04 lenalidomide) –
Revlimid 20 mg hard capsules SPC no longer supplied (L04AX04 lenalidomide) –
Revlimid 25 mg hard capsules SPC no longer supplied (L04AX04 lenalidomide) –
Revlimid 5 mg hard capsules SPC no longer supplied (L04AX04 lenalidomide) –
Revlimid 7.5 mg hard capsules SPC no longer supplied (L04AX04 lenalidomide) –
Rilonacept Regeneron (previously Arcalyst) SPC (L04AC08 canakinumab) –
Rinvoq 15 mg prolonged-release tablets SPC (L04AA Selective immunosuppressants) Prescription only (POM)
Rinvoq 30 mg prolonged-release tablets SPC (L04AA44 upadacitinib) Prescription only (POM)
Roactemra 162 mg solution for injection in Pre-filled pen SPC (L04AC07 tocilizumab) Prescription only (POM)
Roactemra 162 mg solution for injection in Pre-filled syringe SPC (L04AC07 tocilizumab) Prescription only (POM)
Roactemra 20 mg / ml concentrate for solution for infusion SPC (L04AC07 tocilizumab) Prescription only (POM)
Sandimmun concentrate for solution for infusion 50 mg/ml SPC (L04AD01 ciclosporin) –
Sandimmun oral solution SPC (L04AD01 ciclosporin) –
Sandimmun soft Gelatin capsules 25 mg SPC (L04AD01 ciclosporin) –
Sandimmun soft Gelatin capsules 50 mg SPC (L04AD01 ciclosporin) –
Saphnelo 300 mg concentrate for solution for infusion SPC (L04AA Selective immunosuppressants) –
Simponi 100 mg solution for injection in Pre-filled pen SPC (L04AB06 golimumab) Prescription only (POM)
Simponi 45 mg / 0.45 ml solution for injection in Pre-filled pen SPC (L04AB06 golimumab) Prescription only (POM)
Simponi 50 mg solution for injection in Pre-filled pen SPC (L04AB06 golimumab) Prescription only (POM)
Simponi 50 mg solution for injection in Pre-filled syringe SPC (L04AB06 golimumab) Prescription only (POM)
Simulect 10 mg powder and solvent for solution for injection or infusion SPC (L04AC02 basiliximab) –
Simulect 10 mg powder for solution for injection or infusion SPC (L04AC02 basiliximab) –
Simulect 20 mg powder and solvent for solution for injection or infusion SPC (L04AC02 basiliximab) –
Simulect 20 mg powder for solution for injection or infusion SPC (L04AC02 basiliximab) –
Skilarence 120 mg gastro-resistant tablets SPC (L04AX07 dimethyl fumarate) Prescription only (POM)
Skilarence 30 mg gastro-resistant tablets SPC (L04AX07 dimethyl fumarate) Prescription only (POM)
Skyrizi 150 mg solution for injection in Pre-filled pen (L04AC18 risankizumab) Prescription only (POM)
Skyrizi 150 mg solution for injection in Pre-filled syringe SPC (L04AC18 risankizumab) Prescription only (POM)
Skyrizi 180 mg solution for injection in cartridge SPC (L04AC18 risankizumab) Prescription only (POM)
Skyrizi 180 mg solution for injection in Pre-filled syringe SPC (L04AC18 risankizumab) Prescription only (POM)
Skyrizi 360 mg solution for injection in cartridge SPC (L04AC18 risankizumab) Prescription only (POM)
Skyrizi 55 mg solution for injection in Pre-filled syringe SPC (L04AC18 risankizumab) Prescription only (POM)
Skyrizi 600 mg concentrate for solution for infusion (L04AC18 risankizumab) Prescription only (POM)
Skyrizi 75 mg solution for injection in Pre-filled syringe SPC not available (L04AC18 risankizumab) –
Skyrizi 90 mg solution for injection in Pre-filled syringe SPC (L04AC18 risankizumab) Prescription only (POM)
Soliris 300 mg concentrate for solution for infusion SPC (L04AA25 eculizumab) Prescription only (POM)
Solymbic SPC (L04AB04 adalimumab) –
Stelara 130 mg concentrate for solution for infusion (L04AC05 ustekinumab) Prescription only (POM)
Stelara 45 mg solution for injection SPC (L04AC05 ustekinumab) Prescription only (POM)
Stelara 45 mg solution for injection in Pre-filled syringe SPC (L04AC05 ustekinumab) Prescription only (POM)
Stelara 90 mg solution for injection in Pre-filled pen (L04AC05 ustekinumab) Prescription only (POM)
Stelara 90 mg solution for injection in Pre-filled syringe SPC (L04AC05 ustekinumab) Prescription only (POM)
Sylvant SPC (L04AC11 siltuximab) Prescription only (POM)
Sylvant 100 mg powder for concentrate for solution for infusion SPC (L04AC11 siltuximab) Prescription only (POM)
Sylvant 400 mg powder for concentrate for solution for infusion SPC (L04AC11 siltuximab) Prescription only (POM)
Tacforius SPC (L04AD02 tacrolimus) –
Tacforius 0.5 mg prolonged-release hard capsules SPC (L04AD02 tacrolimus) –
Tacforius 3 mg prolonged-release hard capsules SPC (L04AD02 tacrolimus) –
Tacforius 5 mg prolonged-release hard capsules SPC (L04AD02 tacrolimus) –
Tacni 0.5 mg hard capsules SPC no longer supplied (L04AD02 tacrolimus) –
Taltz 40 mg solution for injection in Pre-filled syringe SPC (L04AC13 ixekizumab) Prescription only (POM)
Taltz 80 mg solution for injection in Pre-filled pen (L04AC13 ixekizumab) Prescription only (POM)
Taltz 80 mg solution for injection in Pre-filled syringe (L04AC13 ixekizumab) Prescription only (POM)
Taltz 80 mg solution for injection Pre-filled pen SPC (L04AC Interleukin inhibitors) Prescription only (POM)
Taltz 80 mg solution for injection Pre-filled syringe SPC (L04AC13 ixekizumab) Prescription only (POM)
Tecfidera 120 mg gastro-resistant hard capsules SPC (L04AX07 dimethyl fumarate) Prescription only (POM)
Tecfidera 240 mg gastro-resistant hard capsules SPC (L04AX Other immunosuppressants) Prescription only (POM)
Thalidomide 50 mg capsules hard SPC (L04AX02 thalidomide) Prescription only (POM)
Thalidomide BMS 50 mg hard capsules SPC no longer supplied (L04AX02 thalidomide) –
Thalidomide Celgene (previously Thalidomide Pharmion) SPC (L04AX02 thalidomide) –
Thalidomide Lipomed 100 mg coated tablets SPC (L04AX02 thalidomide) Prescription only (POM)
Thymoglobuline 25 mg powder for solution for infusion SPC (L04AA04 antithymocyte immunoglobulin (rabbit)) Prescription only (POM)

Sources

  • Patient leaflets and SPCs: the MHRA product information (products.mhra.gov.uk) and the European Medicines Agency (EMA)
  • Active substances, ATC codes and legal categories: the NHS Dictionary of Medicines and Devices (dm+d), NHS Business Services Authority
  • World Health Organization (WHO): ATC/DDD classification, group L04A

Contains public sector information licensed under the Open Government Licence v3.0.

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