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L04A Immunosuppressants

ATC group of level 3 – pharmacological subgroup · in plain English: medicines suppressing the immune system, e.g. after a transplant or for autoimmune diseases

This site has the patient leaflet or the SPC of 543 medicines in this group and its subgroups.

Place in the ATC classification

  1. L Antineoplastic and immunomodulating agents 1,791 medicines
    1. L04 Immunosuppressants 545 medicines
      1. L04A Immunosuppressants 543 medicines
        1. L04AA Selective immunosuppressants 115 medicines
        2. L04AB Tumor necrosis factor alpha (TNF-alpha) inhibitors 75 medicines
        3. L04AC Interleukin inhibitors 78 medicines
        4. L04AD Calcineurin inhibitors 69 medicines
        5. L04AX Other immunosuppressants 206 medicines

Medicines in the group and its subgroups

MedicineLegal category
Dimethyl Fumarate Torrent 240 mg gastro-resistant hard capsules (L04AX07 dimethyl fumarate) Prescription only (POM)
Dimethyl Fumarate Wockhardt 120 mg gastro-resistant hard capsules SPC (L04AX07 dimethyl fumarate) Prescription only (POM)
Dimethyl Fumarate Wockhardt 240 mg gastro-resistant hard capsules SPC (L04AX07 dimethyl fumarate) Prescription only (POM)
Ebetrex 10 mg / ml solution for injection Pre-filled syringe SPC (L04AX03 methotrexate) –
Ebetrex 20 mg/ml solution for injection, Pre-filled syringe SPC (L04AX03 methotrexate) –
Emulsoforal 10 mg capsules soft SPC (L04AD01 ciclosporin) –
Emulsoforal 100 mg capsules soft SPC (L04AD01 ciclosporin) –
Enbrel 10 mg powder and solvent for solution for injection for paediatric use SPC (L04AB01 etanercept) Prescription only (POM)
Enbrel 25 mg powder and solvent for solution for injection SPC (L04AB01 etanercept) –
Enbrel 25 mg solution for injection in Pre-filled pen SPC (L04AB01 etanercept) –
Enbrel 25 mg solution for injection in Pre-filled syringe, Enbrel 25 mg solution for injection in Pre-filled pen SPC (L04AB01 etanercept) Prescription only (POM)
Enbrel 50 mg solution for injection in Pre-filled pen SPC (L04AB01 etanercept) Prescription only (POM)
Enbrel 50 mg solution for injection in Pre-filled pen, Enbrel 50 mg solution for injection in Pre-filled syringe SPC (L04AB01 etanercept) Prescription only (POM)
Enspryng 120 mg solution for injection in Pre-filled syringe SPC (L04AC Interleukin inhibitors) Prescription only (POM)
Entyvio 108 mg solution for injection in Pre Filled pen SPC (L04AA Selective immunosuppressants) Prescription only (POM)
Entyvio 108 mg solution for injection in Pre Filled syringe SPC (L04AA33 vedolizumab) Prescription only (POM)
Entyvio 300 mg powder for concentrate for solution for infusion SPC (L04AA33 vedolizumab) Prescription only (POM)
Envarsus 0.75 mg prolonged-release tablets SPC (L04AD02 tacrolimus) Prescription only (POM)
Envarsus 1 mg prolonged-release tablets SPC (L04AD02 tacrolimus) Prescription only (POM)
Envarsus 4 mg prolonged-release tablets (L04AD02 tacrolimus) Prescription only (POM)
Erelzi 25 mg solution for injection in Pre Filled syringe SPC (L04AB01 etanercept) Prescription only (POM)
Erelzi 50 mg solution for injection in Pre Filled pen SPC (L04AB01 etanercept) Prescription only (POM)
Esbriet 267 mg film-coated tablets SPC no longer supplied (L04AX05 pirfenidone) –
Esbriet 267 mg hard capsules SPC no longer supplied (L04AX05 pirfenidone) –
Esbriet 534 mg film-coated tablets SPC no longer supplied (L04AX05 pirfenidone) –
Esbriet 801 mg film-coated tablets SPC no longer supplied (L04AX05 pirfenidone) –
Fingolimod 0.5 mg hard capsules SPC (L04AA27 fingolimod) Prescription only (POM)
Fingolimod Accord 0.5 mg hard capsules (L04AA27 fingolimod) Prescription only (POM)
Fingolimod Aristo 0.5 mg hard capsules SPC (L04AA27 fingolimod) Prescription only (POM)
Fingolimod Fresenius Kabi 0.5 mg hard capsules SPC (L04AA27 fingolimod) Prescription only (POM)
Fingolimod Hydrochloride Sandoz 0.5 mg hard capsules SPC (L04AA27 fingolimod) Prescription only (POM)
Fingolimod Krka 0.5 mg hard capsules SPC (L04AA27 fingolimod) Prescription only (POM)
Fingolimod Mylan SPC (L04AA27 fingolimod) –
Fingolimod Sun 0.5 mg hard capsules SPC (L04AA27 fingolimod) Prescription only (POM)
Fingolimod Teva 0.5 mg capsule hard SPC (L04AA27 fingolimod) Prescription only (POM)
Fingolimod Zentiva 0.5 mg hard capsules SPC (L04AA27 fingolimod) Prescription only (POM)
Flixabi SPC (L04AB02 infliximab) Prescription only (POM)
Flixabi 100 mg powder for concentrate for solution for infusion SPC (L04AB02 infliximab) Prescription only (POM)
Gilenya 0.5 mg hard capsules SPC (L04AA27 fingolimod) Prescription only (POM)
Gobivaz 100 mg solution for injection in Pre-filled pen SPC (L04AB06 golimumab) Prescription only (POM)
Gobivaz 100 mg solution for injection in Pre-filled syringe SPC (L04AB06 golimumab) Prescription only (POM)
Gobivaz 50 mg solution for injection in Pre-filled pen SPC (L04AB06 golimumab) Prescription only (POM)
Gobivaz 50 mg solution for injection in Pre-filled syringe SPC (L04AB06 golimumab) Prescription only (POM)
Hefiya SPC (L04AB04 adalimumab) –
Hukyndra 40 mg solution for injection in Pre-filled syringe SPC (L04AB04 adalimumab) –
Hukyndra 80 mg solution for injection in Pre-filled syringe SPC (L04AB04 adalimumab) –
Hulio (Adalimumab) / 40 mg / solution for injection in prefilled pen (L04AB04 adalimumab) –
Hulio 20 mg solution for injection in Pre-filled syringe SPC no longer supplied (L04AB04 adalimumab) –
Hulio 40 mg / 0.8 ml solution for injection SPC no longer supplied (L04AB04 adalimumab) –
Hulio 40 mg solution for injection in Pre-filled syringe SPC no longer supplied (L04AB04 adalimumab) –
Humira 20 mg solution for injection in Pre-filled syringe SPC (L04AB04 adalimumab) Prescription only (POM)
Humira 40 mg solution for injection in Pre-filled syringe SPC (L04AB04 adalimumab) –
Humira 40 mg solution for injection in Pre-filled syringe, Humira 40 mg solution for injection in Pre-filled pen SPC (L04AB04 adalimumab) –
Humira 80 mg solution for injection in Pre-filled syringe no longer supplied (L04AB04 adalimumab) –
Hyrimoz 20 mg solution for injection in Pre-filled syringe SPC (L04AB04 adalimumab) Prescription only (POM)
Hyrimoz 20 mg/0.2 ml solution for injection in Pre-filled syringe SPC (L04AB04 adalimumab) Prescription only (POM)
Hyrimoz 40 mg solution for injection in Pre-filled syringe SPC (L04AB04 adalimumab) –
Hyrimoz 40 mg/0.4 ml solution for injection in Pre-filled pen SPC (L04AB04 adalimumab) Prescription only (POM)
Hyrimoz 40 mg/0.4 ml solution for injection in Pre-filled syringe SPC (L04AB04 adalimumab) Prescription only (POM)
Hyrimoz 80 mg/0.8 ml solution for injection in Pre-filled syringe SPC (L04AB04 adalimumab) Prescription only (POM)
Idacio 40 mg / 0.8 ml solution for injection for paediatric use SPC (L04AB04 adalimumab) Prescription only (POM)
Idacio 40 mg solution for injection in Pre-filled pen SPC (L04AB04 adalimumab) Prescription only (POM)
Idacio 40 mg solution for injection in Pre-filled syringe SPC (L04AB04 adalimumab) Prescription only (POM)
Idefirix 11 mg powder for concentrate for solution for infusion SPC (L04AA Selective immunosuppressants) Prescription only (POM)
Ilaris SPC (L04AC08 canakinumab) Prescription only (POM)
Ilaris 150 mg powder for solution for injection SPC (L04AC08 canakinumab) Prescription only (POM)
Ilaris 150 mg solution for injection in Pre-filled pen SPC (L04AC08 canakinumab) Prescription only (POM)
Ilaris 150 mg/ml solution for injection SPC (L04AC08 canakinumab) Prescription only (POM)
Ilumetri 100 mg solution for injection in Pre-filled pen (L04AC17 tildrakizumab) Prescription only (POM)
Ilumetri 100 mg solution for injection in Pre-filled syringe SPC (L04AC Interleukin inhibitors) Prescription only (POM)
Ilumetri 200 mg solution for injection in Pre-filled pen SPC (L04AC17 tildrakizumab) Prescription only (POM)
Ilumetri 200 mg solution for injection in Pre-filled syringe SPC (L04AC17 tildrakizumab) Prescription only (POM)
Imnovid (previously Pomalidomide Celgene) SPC (L04AX06 pomalidomide) –
Imnovid 1 mg hard capsules SPC no longer supplied (L04AX06 pomalidomide) –
Imnovid 2 mg hard capsules SPC no longer supplied (L04AX06 pomalidomide) –
Imnovid 4 mg hard capsules no longer supplied (L04AX06 pomalidomide) –
Imraldi SPC (L04AB04 adalimumab) Prescription only (POM)
Imraldi 40 mg / 0.8 ml solution for injection SPC (L04AB04 adalimumab) Prescription only (POM)
Imraldi 40 mg solution for injection in Pre-filled syringe SPC (L04AB04 adalimumab) –
Imuldosa 130 mg concentrate for solution for infusion (L04AC05 ustekinumab) Prescription only (POM)
Imuldosa 45 mg solution for injection in Pre-filled syringe (L04AC05 ustekinumab) Prescription only (POM)
Imuran 25 mg tablets SPC no longer supplied (L04AX01 azathioprine) –
Imuran 50 mg tablets SPC no longer supplied (L04AX01 azathioprine) –
Imuran injection 50 mg / vial SPC no longer supplied (L04AX01 azathioprine) –
Inflectra 100 mg powder for concentrate for solution for infusion SPC no longer supplied (L04AB02 infliximab) –
Inzolfi 0.5 mg hard capsules SPC (L04AA27 fingolimod) –
Jayempi SPC (L04AX01 azathioprine) Prescription only (POM)
Jayempi 10 mg / ml oral suspension SPC (L04AX01 azathioprine) Prescription only (POM)
Jylamvo 2 mg/ml oral solution (L04AX03 methotrexate) Prescription only (POM)
Jyseleca 100 mg film-coated tablets SPC (L04AA45 filgotinib) Prescription only (POM)
Jyseleca 200 mg film-coated tablets SPC (L04AA Selective immunosuppressants) Prescription only (POM)
Kevzara 150 mg solution for injection in Pre-filled pen (L04AC14 sarilumab) Prescription only (POM)
Kevzara 175 mg/ml solution for injection (L04AC14 sarilumab) Prescription only (POM)
Kevzara 200 mg solution for injection in Pre-filled pen SPC (L04AC14 sarilumab) Prescription only (POM)
Kevzara 200 mg solution for injection in Pre-filled syringe SPC (L04AC14 sarilumab) Prescription only (POM)
Kineret 100 mg / 0.67 ml solution for injection in Pre-filled syringe SPC (L04AC03 anakinra) Prescription only (POM)
Kromeya SPC (L04AB04 adalimumab) –
Kyntheum 210 mg solution for injection in Pre-filled syringe SPC (L04AC12 brodalumab) Prescription only (POM)
Leflunomide 10 mg film-coated tablets SPC (L04AA13 leflunomide) Prescription only (POM)
Leflunomide 10 mg tablets SPC (L04AA13 leflunomide) Prescription only (POM)

Sources

  • Patient leaflets and SPCs: the MHRA product information (products.mhra.gov.uk) and the European Medicines Agency (EMA)
  • Active substances, ATC codes and legal categories: the NHS Dictionary of Medicines and Devices (dm+d), NHS Business Services Authority
  • World Health Organization (WHO): ATC/DDD classification, group L04A

Contains public sector information licensed under the Open Government Licence v3.0.

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