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L03A Immunostimulants

ATC group of level 3 – pharmacological subgroup · in plain English: medicines boosting the immune system

This site has the patient leaflet or the SPC of 93 medicines in this group and its subgroups.

Place in the ATC classification

  1. L Antineoplastic and immunomodulating agents 1,791 medicines
    1. L03 Immunostimulants 93 medicines
      1. L03A Immunostimulants 93 medicines
        1. L03AA Colony stimulating factors 40 medicines
        2. L03AB Interferons 31 medicines
        3. L03AC Interleukins 2 medicines
        4. L03AX Other immunostimulants 20 medicines

Active substances in the group

Medicines in the group and its subgroups

MedicineLegal category
Accofil SPC (L03AA02 filgrastim) Prescription only (POM)
Accofil 12 MU/0.2 ml solution for injection or infusion in Pre-filled syringe SPC (L03AA02 filgrastim) Prescription only (POM)
Accofil 30 MU/0.5 ml solution for injection or infusion in Pre Filled syringe (L03AA02 filgrastim) Prescription only (POM)
Accofil 70 MU/0.73 ml solution for injection or infusion in Pre-filled syringe (L03AA02 filgrastim) Prescription only (POM)
Avonex SPC (L03AB07 interferon beta-1a) Prescription only (POM)
Avonex 30 micrograms / 0.5 ml solution for injection in Pre-filled pen SPC (L03AB07 interferon beta-1a) Prescription only (POM)
Avonex 30 micrograms/0.5 ml solution for injection in Pre-filled syringe SPC (L03AB07 interferon beta-1a) Prescription only (POM)
BCG Medac 2 x 10^8 - 1.5 x 10^9 Cfu powder and solvent for intravesical suspension SPC (L03AX03 BCG vaccine) –
BCG Medac 2 x 10^8 - 1.5 x 10^9 Cfu powder for intravesical suspension SPC (L03AX03 BCG vaccine) –
BCG vaccine Ajv, powder and solvent for suspension for injection. (L03AX03 BCG vaccine) –
Beromun SPC (L03AX11 tasonermin) Prescription only (POM)
Besremi SPC (L03AB15 ropeginterferon alfa-2b) Prescription only (POM)
Besremi 250 mg / 0.5 ml solution for injection in Pre-filled pen SPC (L03AB15 ropeginterferon alfa-2b) Prescription only (POM)
Besremi 250 micrograms/0.5 ml solution for injection in Pre-filled pen (L03AB15 ropeginterferon alfa-2b) Prescription only (POM)
Besremi 500 mg / 0.5 ml solution for injection in Pre-filled pen SPC (L03AB15 ropeginterferon alfa-2b) Prescription only (POM)
Betaferon 250 micrograms / ml powder and solvent for solution for injection SPC (L03AB08 interferon beta-1b) Prescription only (POM)
Biograstim SPC (L03AA02 filgrastim) –
Brabio 20 mg / ml solution for injection Pre-filled syringe SPC (L03AX13 glatiramer acetate) Prescription only (POM)
Brabio 40 mg / ml solution for injection Pre-filled syringe SPC (L03AX13 glatiramer acetate) Prescription only (POM)
Cegfila (previously Pegfilgrastim Mundipharma) SPC (L03AA13 pegfilgrastim) –
Ceplene SPC no longer supplied (L03AX14 histamine dihydrochloride) –
Copaxone 20 mg / ml solution for injection Pre-filled syringe SPC (L03AX13 glatiramer acetate) Prescription only (POM)
Copaxone 40 mg / ml solution for injection Pre-filled syringe SPC (L03AX13 glatiramer acetate) Prescription only (POM)
Dyrupeg 6 mg solution for injection in a Pre-filled syringe SPC (L03AA13 pegfilgrastim) Prescription only (POM)
Extavia SPC no longer supplied (L03AB08 interferon beta-1b) –
Extavia 250 mcg/ml powder and solvent for solution for injection SPC no longer supplied (L03AB08 interferon beta-1b) –
Filgrastim Hexal SPC (L03AA02 filgrastim) –
Filgrastim ratiopharm SPC (L03AA02 filgrastim) –
Fulphila 6 mg solution for injection in Pre-filled syringe SPC (L03AA13 pegfilgrastim) –
Granocyte 13 million IU/ml powder and solvent for solution for injection/infusion in a PFS SPC (L03AA10 lenograstim) Prescription only (POM)
Grastofil SPC (L03AA02 filgrastim) –
Grasustek SPC (L03AA13 pegfilgrastim) –
Histamine Dihydrochloride 0.5 mg/0.5 ml solution for injection SPC not available (L03AX14 histamine dihydrochloride) –
Immukin 2 x 10 000 000 IU (0.1 mg) solution for injection (L03AB03 interferon gamma) Prescription only (POM)
IntronA SPC no longer supplied (L03AB05 interferon alfa-2b) –
Lonquex 6 mg solution for injection in Pre-filled syringe SPC (L03AA14 lipegfilgrastim) Prescription only (POM)
Mepact SPC no longer supplied (L03AX15 mifamurtide) –
Methoxsalen G.L. Pharma 20 microgram/ml solution for Blood Fraction Modification SPC (L03AX Other immunostimulants) –
Methoxsalen Macopharma 20 micrograms / ml solution for Blood Fraction Modification SPC (L03AX Other immunostimulants) –
Mifamurtide 4 mg powder for concentrate for Dispersion for infusion SPC (L03AX15 mifamurtide) Prescription only (POM)
Mozobil SPC no longer supplied (L03AX16 plerixafor) –
Mozobil 20 mg / ml solution for injection SPC no longer supplied (L03AX16 plerixafor) –
Neulasta SPC (L03AA13 pegfilgrastim) Prescription only (POM)
Neulasta 6 mg solution for injection SPC (L03AA13 pegfilgrastim) Prescription only (POM)
Neupogen Singleject 30 MU/0.5 ml solution for injection SPC (L03AA02 filgrastim) Prescription only (POM)
Neupogen Singleject 30 MU/0.5 ml solution for injection in a Pre-filled syringe SPC (L03AA02 filgrastim) Prescription only (POM)
Neupogen Singleject 48 MU/0.5 ml solution for injection in a Pre-filled syringe SPC (L03AA02 filgrastim) Prescription only (POM)
Neupopeg SPC (L03AA13 pegfilgrastim) –
Nivestim 12 MU/0.2 ml solution for injection/infusion SPC (L03AA02 filgrastim) Prescription only (POM)
Nivestim 30 MU/0.5 ml solution for injection/infusion SPC (L03AA02 filgrastim) Prescription only (POM)
Nivestim 48 MU/0.5 ml solution for injection/infusion SPC (L03AA02 filgrastim) Prescription only (POM)
Nyvepria SPC (L03AA13 pegfilgrastim) –
Pegasys 135 micrograms solution for injection in Pre-filled syringe SPC (L03AB11 peginterferon alfa-2a) Prescription only (POM)
Pegasys 180 micrograms solution for injection SPC no longer supplied (L03AB11 peginterferon alfa-2a) –
Pegasys 180 micrograms solution for injection in Pre-filled syringe SPC (L03AB11 peginterferon alfa-2a) Prescription only (POM)
Pegasys 90 micrograms solution for injection in Pre-filled syringe SPC (L03AB11 peginterferon alfa-2a) Prescription only (POM)
PegIntron SPC no longer supplied (L03AB10 peginterferon alfa-2b) –
Pelgraz 6 mg solution for injection in Pre-filled Injector SPC (L03AA13 pegfilgrastim) Prescription only (POM)
Pelgraz 6 mg solution for injection in Pre-filled syringe SPC (L03AA13 pegfilgrastim) Prescription only (POM)
Pelmeg 6 mg solution for injection in Pre-filled syringe SPC (L03AA13 pegfilgrastim) Prescription only (POM)
Plegridy 125 micrograms solution for injection in Pre Filled pen SPC (L03AB13 peginterferon beta-1a) Prescription only (POM)
Plegridy 125 micrograms solution for injection in Pre Filled syringe (L03AB13 peginterferon beta-1a) Prescription only (POM)
Plegridy 63/94 micrograms solution for injection in Pre Filled pen SPC (L03AB13 peginterferon beta-1a) –
Plegridy 63/94 micrograms solution for injection in Pre Filled syringe SPC (L03AB13 peginterferon beta-1a) –
Plerixafor 20 mg/ml solution for injection SPC (L03AX16 plerixafor) Prescription only (POM)
Plerixafor Seacross 20 mg/ml solution for injection (L03AX16 plerixafor) Prescription only (POM)
Proleukin 18 million IU powder for solution for injection or infusion SPC (L03AC01 aldesleukin) Prescription only (POM)
Proleukin powder for Parenteral use 1 mg SPC (L03AC01 aldesleukin) –
Provenge SPC (L03AX17 sipuleucel-T) –
Ratiograstim SPC no longer supplied (L03AA02 filgrastim) –
Ratiograstim 30 MIU/0.5 ml solution for injection/infusion SPC no longer supplied (L03AA02 filgrastim) –
Rebif 22 micrograms / 0.25 ml solution for injection in cartridge, Rebif 8.8 micrograms / 0.1 ml solution for injection in cartridge SPC (L03AB07 interferon beta-1a) –
Rebif 22 micrograms / 0.5 ml solution for injection in cartridge SPC (L03AB07 interferon beta-1a) –
Rebif 22 micrograms / 0.5 ml solution for injection in Pre-filled pen SPC (L03AB07 interferon beta-1a) Prescription only (POM)
Rebif 44 micrograms / 0.5 ml solution for injection in cartridge SPC (L03AB07 interferon beta-1a) –
Rebif 44 micrograms solution for injection in Pre-filled pen SPC (L03AB07 interferon beta-1a) Prescription only (POM)
Rebif 44 micrograms solution for injection in Pre-filled syringe SPC (L03AB07 interferon beta-1a) Prescription only (POM)
Rebif 8.8 micrograms solution for injection in Pre-filled pen, Rebif 22 micrograms solution for injection in Pre-filled pen (L03AB07 interferon beta-1a) Prescription only (POM)
Rebif 8.8 micrograms solution for injection in Pre-filled syringe, Rebif 22 micrograms solution for injection in Pre-filled syringe SPC (L03AB07 interferon beta-1a) Prescription only (POM)
Ristempa SPC (L03AA13 pegfilgrastim) –
Strimvelis 1-10 million Cells/ml Dispersion for infusion SPC (L03AX Other immunostimulants) Prescription only (POM)
Tevagrastim SPC no longer supplied (L03AA02 filgrastim) –
Tevagrastim 30 MIU/0.5 ml solution for injection/infusion no longer supplied (L03AA02 filgrastim) –
Tevagrastim 48 MIU/0.8 ml solution for injection/infusion SPC no longer supplied (L03AA02 filgrastim) –
Udenyca SPC (L03AA13 pegfilgrastim) –
Viraferon SPC no longer supplied (L03AB05 interferon alfa-2b) –
ViraferonPeg SPC no longer supplied (L03AB10 peginterferon alfa-2b) –
Zarzio 30 MU/0.5 ml solution for injection or infusion in Pre-filled syringe SPC (L03AA02 filgrastim) Prescription only (POM)
Zarzio 48 MU/0.5 ml solution for injection or infusion in Pre-filled syringe SPC (L03AA02 filgrastim) Prescription only (POM)
Zefylti 30 MU/0.5 ml solution for injection/ infusion in Pre-filled syringe SPC (L03AA02 filgrastim) Prescription only (POM)
Zefylti 48 MU/0.5 ml solution for injection/infusion in Pre-filled syringe SPC (L03AA02 filgrastim) Prescription only (POM)
Ziextenzo SPC no longer supplied (L03AA13 pegfilgrastim) –
Ziextenzo 6 mg solution for injection in Pre-filled syringe SPC no longer supplied (L03AA13 pegfilgrastim) –

Other names of the ATC group

Sources

  • Patient leaflets and SPCs: the MHRA product information (products.mhra.gov.uk) and the European Medicines Agency (EMA)
  • Active substances, ATC codes and legal categories: the NHS Dictionary of Medicines and Devices (dm+d), NHS Business Services Authority
  • World Health Organization (WHO): ATC/DDD classification, group L03A

Contains public sector information licensed under the Open Government Licence v3.0.

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