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L01 Antineoplastic agents

ATC group of level 2 – therapeutic subgroup · in plain English: cancer medicines

This site has the patient leaflet or the SPC of 1,025 medicines in this group and its subgroups.

Place in the ATC classification

  1. L Antineoplastic and immunomodulating agents 1,791 medicines
    1. L01 Antineoplastic agents 1,025 medicines
      1. L01A Alkylating agents 123 medicines
      2. L01B Antimetabolites 182 medicines
      3. L01C Plant alkaloids and other natural products, antineoplastic drugs 97 medicines
      4. L01D Cytotoxic antibiotics and related substances 42 medicines
      5. L01E Protein kinase inhibitors, antineoplastic and immunomodulating agents 353 medicines
      6. L01X Other antineoplastic agents 225 medicines

Medicines in the group and its subgroups

MedicineLegal category
Irinotecan Hydrochloride 20 mg / ml concentrate for solution for infusion SPC (L01CE02 irinotecan) –
Irinotecan Hydrochloride Medac 20 mg / ml concentrate for solution for infusion SPC (L01CE02 irinotecan) –
Ivozall SPC (L01BB06 clofarabine) –
Ixazomib 3 mg hard capsules SPC (L01XG03 ixazomib) Prescription only (POM)
Ixazomib 4 mg hard capsules SPC (L01XG03 ixazomib) Prescription only (POM)
Jakavi 10 mg tablets SPC (L01EJ01 ruxolitinib) Prescription only (POM)
Jakavi 15 mg tablets SPC (L01EJ01 ruxolitinib) Prescription only (POM)
Jakavi 20 mg tablets SPC (L01EJ01 ruxolitinib) Prescription only (POM)
Jakavi 5 mg tablets SPC (L01EJ01 ruxolitinib) Prescription only (POM)
Jakavi 5 mg/ml oral solution SPC (L01EJ01 ruxolitinib) Prescription only (POM)
Javlor SPC no longer supplied (L01CA05 vinflunine) –
Jemperli 500 mg concentrate for solution for infusion SPC (L01XC40 dostarlimab) Prescription only (POM)
Jevtana SPC no longer supplied (L01CD Taxanes, antineoplastic) –
Jevtana 60 mg concentrate and solvent for solution for infusion SPC no longer supplied (L01CD04 cabazitaxel) –
Jylamvo 2 mg/ml oral solution (L01BA01 methotrexate) Prescription only (POM)
Kadcyla 100 mg powder for concentrate for solution for infusion SPC (L01XC14 trastuzumab emtansine) Prescription only (POM)
Kadcyla 160 mg powder for concentrate for solution for infusion SPC (L01XC14 trastuzumab emtansine) Prescription only (POM)
Kanjinti SPC no longer supplied (L01XC03 trastuzumab) –
Kanjinti 420 mg powder for concentrate for solution for infusion SPC no longer supplied (L01XC03 trastuzumab) –
Kisplyx 10 mg hard capsules SPC (L01EX08 lenvatinib) Prescription only (POM)
Kisplyx 4 mg hard capsules SPC (L01EX08 lenvatinib) Prescription only (POM)
Kisqali 200 mg film-coated tablets SPC (L01EF02 ribociclib) Prescription only (POM)
Koselugo 10 mg hard capsule SPC (L01EE04 selumetinib) Prescription only (POM)
Koselugo 25 mg hard capsules SPC (L01EE04 selumetinib) Prescription only (POM)
Koselugo 5 mg granules in capsule for Opening (L01EE04 selumetinib) Prescription only (POM)
Koselugo 7.5 mg granules in capsule for Opening SPC (L01EE04 selumetinib) Prescription only (POM)
Kymriah 1.2 x 10^6 - 6 x 10^8 Cells Dispersion for infusion SPC (L01XX71 tisagenlecleucel) Prescription only (POM)
Kyprolis (Carfilzomib) 10 mg powder for solution for infusion SPC (L01XG02 carfilzomib) Prescription only (POM)
Kyprolis (Carfilzomib) 30 mg powder for solution for infusion SPC (L01XG02 carfilzomib) Prescription only (POM)
Kyprolis 10 mg powder for solution for infusion (L01XG02 carfilzomib) Prescription only (POM)
Kyprolis 30 mg powder for solution for infusion (L01XG02 carfilzomib) Prescription only (POM)
Lartruvo SPC (L01XC27 olaratumab) –
Ledaga 160 mcg/g gel SPC (L01AA05 chlormethine) Prescription only (POM)
Lenvatinib 10 mg hard capsules SPC (L01EX08 lenvatinib) Prescription only (POM)
Lenvatinib 4 mg hard capsules SPC (L01EX08 lenvatinib) Prescription only (POM)
Lenvatinib Torrent 10 mg hard capsules SPC (L01EX08 lenvatinib) Prescription only (POM)
Lenvima 10 mg hard capsules SPC (L01EX08 lenvatinib) Prescription only (POM)
Lenvima 4 mg hard capsules (L01EX08 lenvatinib) Prescription only (POM)
Leustat subcutaneous 2 mg/ml solution for injection SPC (L01BB04 cladribine) –
Levact 2.5 mg / ml powder for concentrate for solution for infusion SPC no longer supplied (L01AA09 bendamustine) –
Lextemy SPC (L01XC07 bevacizumab) –
Libtayo 350 mg concentrate for solution for infusion (L01XC33 cemiplimab) Prescription only (POM)
Litak 2 mg/ml solution for injection SPC (L01BB04 cladribine) Prescription only (POM)
Lomustine Medac 40 mg SPC (L01AD02 lomustine) Prescription only (POM)
Lonsurf SPC (L01BC Pyrimidine analogues, antineoplastic antimetabolites) Prescription only (POM)
Lonsurf 15 mg / 6.14 mg film-coated tablets SPC (L01BC59 trifluridine, combinations) Prescription only (POM)
Lorviqua 100 mg film-coated tablets SPC (L01ED05 lorlatinib) Prescription only (POM)
Lorviqua 25 mg film-coated tablets SPC (L01ED05 lorlatinib) Prescription only (POM)
Lumoxiti SPC (L01X Other antineoplastic agents) –
Lynparza 100 mg film-coated tablets SPC (L01XK01 olaparib) Prescription only (POM)
Lynparza 150 mg film-coated tablets SPC (L01XK01 olaparib) Prescription only (POM)
Lynparza 50 mg capsules SPC no longer supplied (L01XK01 olaparib) –
Lysodren SPC no longer supplied (L01XX23 mitotane) –
Lysodren 500 mg tablets SPC no longer supplied (L01XX23 mitotane) –
MabThera SPC (L01XC02 rituximab) Prescription only (POM)
Mabthera 1600 mg solution for subcutaneous injection SPC (L01XC02 rituximab) Prescription only (POM)
Mabthera 500 mg concentrate for solution for infusion SPC (L01XC02 rituximab) Prescription only (POM)
Mekinist 0.5 mg film-coated tablets SPC (L01EE01 trametinib) Prescription only (POM)
Mekinist 2 mg film-coated tablets SPC (L01EE01 trametinib) Prescription only (POM)
Mektovi 15 mg film-coated tablets SPC (L01EE03 binimetinib) Prescription only (POM)
Mektovi 45 mg film-coated tablets (L01EE03 binimetinib) Prescription only (POM)
Melphalan 2 mg tablets SPC (L01AA03 melphalan) Prescription only (POM)
Melphalan 50 mg concentrate and solvent for solution for injection/infusion (L01AA03 melphalan) Prescription only (POM)
Melphalan 50 mg powder and solvent for solution for injection/infusion SPC (L01AA03 melphalan) Prescription only (POM)
Mercaptopurine 50 mg tablets SPC (L01BB02 mercaptopurine) Prescription only (POM)
Mercaptopurine 50 mg tablets,Puri-nethol 50 mg tablets (L01BB02 mercaptopurine) Prescription only (POM)
Mercaptopurine Silver Pharma 50 mg tablets SPC (L01BB02 mercaptopurine) –
Methotrexate 100 mg / ml injection SPC (L01BA01 methotrexate) Prescription only (POM)
Methotrexate 100 mg / ml injection BP (L01BA01 methotrexate) Prescription only (POM)
Methotrexate 100 mg / ml solution for injection SPC (L01BA01 methotrexate) Prescription only (POM)
Methotrexate 100 mg/ml concentrate for solution for infusion SPC (L01BA01 methotrexate) Prescription only (POM)
Methotrexate 2.5 mg / ml injection SPC (L01BA01 methotrexate) Prescription only (POM)
Methotrexate 2.5 mg / ml solution for injection SPC (L01BA01 methotrexate) Prescription only (POM)
Methotrexate 25 mg / ml solution for injection SPC (L01BA01 methotrexate) –
Methotrexate 25 mg / ml solution for injection Pre-filled syringe SPC (L01BA01 methotrexate) –
Metoject 50 mg / ml solution for injection SPC no longer supplied (L01BA01 methotrexate) –
Metvix 160 mg/g cream SPC (L01XD03 methyl aminolevulinate) Prescription only (POM)
Minjuvi 200 mg powder for concentrate for solution for infusion SPC (L01XC35 tafasitamab) Prescription only (POM)
Mitocin 20 mg powder and solvent for intravesical solution no longer supplied (L01DC03 mitomycin) –
Mitocin 20 mg powder for solution for injection/infusion or intravesical use SPC (L01DC03 mitomycin) Prescription only (POM)
Mitomycin 10 mg powder for solution for injection/infusion or intravesical use SPC no longer supplied (L01DC03 mitomycin) –
Mitomycin 2 mg powder for solution for injection/infusion or intravesical use SPC no longer supplied (L01DC03 mitomycin) –
Mitomycin 20 mg powder for solution for injection/infusion or intravesical use SPC no longer supplied (L01DC03 mitomycin) –
Mitomycin 40 mg powder and solvent for intravesical solution SPC (L01DC03 mitomycin) Prescription only (POM)
Mitomycin 40 mg powder for solution for injection/infusion SPC (L01DC03 mitomycin) Prescription only (POM)
Mitotane Esteve 500 mg tablets (L01XX23 mitotane) Prescription only (POM)
Mitoxantrone 2 mg / ml Sterile concentrate SPC (L01DB07 mitoxantrone) –
Mitoxantrone 2 mg/ml concentrate for solution for infusion SPC no longer supplied (L01DB07 mitoxantrone) –
Mvasi SPC (L01XC07 bevacizumab) –
Mvasi 25 mg / ml Concentration for solution for infusion SPC (L01XC07 bevacizumab) –
Mylotarg 5 mg powder for concentrate for solution for infusion SPC (L01XC05 gemtuzumab ozogamicin) Prescription only (POM)
Myocet liposomal (previously Myocet) SPC (L01DB01 doxorubicin) –
Myocet liposomal 50 mg powder Dispersion and solvent for concentrate for Dispersion for infusion SPC (L01DB01 doxorubicin) –
Navelbine 10 mg / ml concentrate for solution for infusion (L01CA04 vinorelbine) Prescription only (POM)
Navelbine 20 mg soft capsule SPC (L01CA04 vinorelbine) Prescription only (POM)
Navelbine 30 mg soft capsule SPC (L01CA04 vinorelbine) Prescription only (POM)
Navelbine 80 mg soft capsule SPC (L01CA04 vinorelbine) Prescription only (POM)
Naveruclif 5 mg/ml powder for Dispersion for infusion SPC (L01CD01 paclitaxel) Prescription only (POM)
Nerlynx 40 mg film-coated tablets SPC (L01EH02 neratinib) Prescription only (POM)
Nexalboz 5 mg/ml powder for Dispersion for infusion SPC (L01CD01 paclitaxel) Prescription only (POM)

Sources

  • Patient leaflets and SPCs: the MHRA product information (products.mhra.gov.uk) and the European Medicines Agency (EMA)
  • Active substances, ATC codes and legal categories: the NHS Dictionary of Medicines and Devices (dm+d), NHS Business Services Authority
  • World Health Organization (WHO): ATC/DDD classification, group L01

Contains public sector information licensed under the Open Government Licence v3.0.

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