Medicines by ATC code B01AF Direct factor Xa inhibitors

Place in the ATC classification

How to read ATC codes – what the levels mean and what a code does not tell you.

B Blood and blood forming organ drugs 1,013 medicines
1. B01 Antithrombotic agents 447 medicines
  1. B01A Antithrombotic agents 445 medicines
    1. B01AF Direct factor Xa inhibitors 117 medicines
      1. B01AF01 rivaroxaban 81 medicines
      2. B01AF02 apixaban 26 medicines
      3. B01AF03 edoxaban 10 medicines

1 more subgroup has no medicine with a leaflet on this site.

Active substances in the group

Apixaban 26 medicines
Edoxaban 10 medicines
Rivaroxaban 81 medicines

Medicines in the group and its subgroups

Medicine	Legal category
Apixaban 1 mg/ml oral suspension SPC (B01AF02 apixaban)	Prescription only (POM)
Apixaban 2.5 mg film-coated tablets SPC (B01AF02 apixaban)	Prescription only (POM)
Apixaban 2.5 mg hard capsules SPC (B01AF02 apixaban)	–
Apixaban 5 mg film-coated tablets SPC (B01AF02 apixaban)	Prescription only (POM)
Apixaban 5 mg hard capsules SPC (B01AF02 apixaban)	–
Apixaban Abdi 5 mg film-coated tablet SPC (B01AF02 apixaban)	Prescription only (POM)
Apixaban Accord SPC (B01AF02 apixaban)	–
Apixaban Accord 2.5 mg film-coated tablets SPC (B01AF02 apixaban)	Prescription only (POM)
Apixaban Accord 5 mg film-coated tablets SPC (B01AF02 apixaban)	Prescription only (POM)
Apixaban Krka 2.5 mg film-coated tablets SPC (B01AF02 apixaban)	Prescription only (POM)
Apixaban Krka 5 mg film-coated tablets (B01AF02 apixaban)	Prescription only (POM)
Apixaban Macleods 5 mg film-coated tablets (B01AF02 apixaban)	Prescription only (POM)
Apixaban Milpharm 2.5 mg film-coated tablets SPC (B01AF02 apixaban)	Prescription only (POM)
Apixaban Milpharm 5 mg film-coated tablets SPC (B01AF02 apixaban)	Prescription only (POM)
Apixaban Mylan 2.5 mg film-coated tablets SPC no longer supplied (B01AF02 apixaban)	–
Apixaban Mylan 5 mg film-coated tablets SPC (B01AF02 apixaban)	Prescription only (POM)
Apixaban Sandoz 2.5 mg film-coated tablets SPC (B01AF02 apixaban)	Prescription only (POM)
Apixaban Sandoz 5 mg film-coated tablets SPC (B01AF02 apixaban)	Prescription only (POM)
Apixaban Teva 2.5 mg film-coated tablets SPC (B01AF02 apixaban)	Prescription only (POM)
Apixaban Teva 5 mg film-coated tablets SPC (B01AF02 apixaban)	Prescription only (POM)
Apixaban Torrent 2.5 mg film-coated tablets SPC (B01AF02 apixaban)	Prescription only (POM)
Apixaban Torrent 5 mg film-coated tablets SPC (B01AF02 apixaban)	Prescription only (POM)
Apixaban Umedica 2.5 mg film-coated tablets SPC (B01AF02 apixaban)	Prescription only (POM)
Apixaban Umedica 5 mg film-coated tablets SPC (B01AF02 apixaban)	Prescription only (POM)
Edoxaban 15 mg film-coated tablets SPC (B01AF03 edoxaban)	Prescription only (POM)
Edoxaban 30 mg film-coated tablets SPC (B01AF03 edoxaban)	Prescription only (POM)
Edoxaban 60 mg film-coated tablets SPC (B01AF03 edoxaban)	Prescription only (POM)
Edoxaban Krka 15 mg film-coated tablets SPC (B01AF03 edoxaban)	Prescription only (POM)
Edoxaban Krka 30 mg film-coated tablets SPC (B01AF03 edoxaban)	Prescription only (POM)
Edoxaban Krka 60 mg film-coated tablets (B01AF03 edoxaban)	Prescription only (POM)
Eliquis 2.5 mg film-coated tablets SPC (B01AF02 apixaban)	Prescription only (POM)
Eliquis 5 mg film-coated tablets SPC (B01AF02 apixaban)	Prescription only (POM)
Lixiana 15 mg film-coated tablets SPC (B01AF03 edoxaban)	Prescription only (POM)
Lixiana 30 mg film-coated tablets (B01AF03 edoxaban)	Prescription only (POM)
Lixiana, 60 mg film-coated tablets SPC (B01AF03 edoxaban)	Prescription only (POM)
Rivaroxaban 10 mg film-coated tablets SPC (B01AF01 rivaroxaban)	Prescription only (POM)
Rivaroxaban 15 mg & 20 mg film-coated tablets treatment Initiation Pack SPC (B01AF01 rivaroxaban)	–
Rivaroxaban 15 mg film-coated tablets SPC (B01AF01 rivaroxaban)	Prescription only (POM)
Rivaroxaban 15 mg film-coated tablets, Rivaroxaban 20 mg film-coated tablets SPC (B01AF01 rivaroxaban)	Prescription only (POM)
Rivaroxaban 2.5 mg film-coated tablets SPC (B01AF01 rivaroxaban)	Prescription only (POM)
Rivaroxaban 20 mg film-coated tablets SPC (B01AF01 rivaroxaban)	Prescription only (POM)
Rivaroxaban 20 mg hard capsules SPC (B01AF01 rivaroxaban)	Prescription only (POM)
Rivaroxaban 5 mg /ml oral suspension (B01AF01 rivaroxaban)	Prescription only (POM)
Rivaroxaban Abdi 10 mg film-coated tablets SPC (B01AF01 rivaroxaban)	Prescription only (POM)
Rivaroxaban Abdi 15 mg film-coated tablets SPC (B01AF01 rivaroxaban)	Prescription only (POM)
Rivaroxaban Abdi 2.5 mg film-coated tablets (B01AF01 rivaroxaban)	Prescription only (POM)
Rivaroxaban Abdi 20 mg film-coated tablets SPC (B01AF01 rivaroxaban)	Prescription only (POM)
Rivaroxaban Accord 10 mg film-coated tablets SPC (B01AF01 rivaroxaban)	Prescription only (POM)
Rivaroxaban Accord 15 mg film-coated tablets SPC (B01AF01 rivaroxaban)	Prescription only (POM)
Rivaroxaban Accord 2.5 mg film-coated tablets SPC (B01AF01 rivaroxaban)	Prescription only (POM)
Rivaroxaban Accord 20 mg film-coated tablets SPC (B01AF01 rivaroxaban)	Prescription only (POM)
Rivaroxaban Bluefish 10 mg film-coated tablets (B01AF01 rivaroxaban)	Prescription only (POM)
Rivaroxaban Bluefish 15 mg film-coated tablets SPC (B01AF01 rivaroxaban)	Prescription only (POM)
Rivaroxaban Bluefish 15 mg film-coated tablets + Rivaroxaban Bluefish 20 mg film-coated tablets SPC (B01AF01 rivaroxaban)	Prescription only (POM)
Rivaroxaban Bluefish 20 mg film-coated tablets SPC (B01AF01 rivaroxaban)	Prescription only (POM)
Rivaroxaban DR Reddys 10 mg film-coated tablets SPC (B01AF01 rivaroxaban)	Prescription only (POM)
Rivaroxaban DR Reddys 15 mg film-coated tablets SPC (B01AF01 rivaroxaban)	Prescription only (POM)
Rivaroxaban DR Reddys 2.5 mg film-coated tablets SPC (B01AF01 rivaroxaban)	Prescription only (POM)
Rivaroxaban DR Reddys 20 mg film-coated tablets SPC (B01AF01 rivaroxaban)	Prescription only (POM)
Rivaroxaban Gedeon Richter 10 mg film-coated tablets SPC (B01AF01 rivaroxaban)	Prescription only (POM)
Rivaroxaban Gedeon Richter 2.5 mg film-coated tablets SPC (B01AF01 rivaroxaban)	Prescription only (POM)
Rivaroxaban Grindeks 20 mg film-coated tablets SPC (B01AF01 rivaroxaban)	Prescription only (POM)
Rivaroxaban Jubilant 10 mg film-coated tablets SPC (B01AF01 rivaroxaban)	Prescription only (POM)
Rivaroxaban Jubilant 15 mg film-coated tablets SPC (B01AF01 rivaroxaban)	Prescription only (POM)
Rivaroxaban Jubilant 2.5 mg film-coated tablets SPC (B01AF01 rivaroxaban)	Prescription only (POM)
Rivaroxaban Jubilant 20 mg film-coated tablets SPC (B01AF01 rivaroxaban)	Prescription only (POM)
Rivaroxaban Krka 10 mg film-coated tablets SPC (B01AF01 rivaroxaban)	Prescription only (POM)
Rivaroxaban Krka 15 mg film-coated tablets (B01AF01 rivaroxaban)	Prescription only (POM)
Rivaroxaban Krka 2.5 mg film-coated tablets (B01AF01 rivaroxaban)	Prescription only (POM)
Rivaroxaban Krka 20 mg film-coated tablets SPC (B01AF01 rivaroxaban)	Prescription only (POM)
Rivaroxaban Medana 10 mg film-coated tablets SPC (B01AF01 rivaroxaban)	Prescription only (POM)
Rivaroxaban Medana 15 mg + 20 mg film-coated tablets SPC (B01AF01 rivaroxaban)	–
Rivaroxaban Medana 15 mg film-coated tablets SPC (B01AF01 rivaroxaban)	Prescription only (POM)
Rivaroxaban Medana 2.5 mg film-coated tablets SPC (B01AF01 rivaroxaban)	Prescription only (POM)
Rivaroxaban Medana 20 mg film-coated tablets SPC (B01AF01 rivaroxaban)	Prescription only (POM)
Rivaroxaban Milpharm 10 mg film-coated tablets SPC (B01AF01 rivaroxaban)	Prescription only (POM)
Rivaroxaban Milpharm 15 mg film-coated tablets SPC (B01AF01 rivaroxaban)	Prescription only (POM)
Rivaroxaban Milpharm 15 mg film-coated tablets / Rivaroxaban Milpharm 20 mg film-coated SPC (B01AF01 rivaroxaban)	Prescription only (POM)
Rivaroxaban Milpharm 20 mg film-coated tablets SPC (B01AF01 rivaroxaban)	Prescription only (POM)
Rivaroxaban Mylan SPC (B01AF01 rivaroxaban)	–
Rivaroxaban Polpharma 10 mg film-coated tablets SPC (B01AF01 rivaroxaban)	Prescription only (POM)
Rivaroxaban Polpharma 15 mg film-coated tablets SPC (B01AF01 rivaroxaban)	Prescription only (POM)
Rivaroxaban Polpharma 2.5 mg film-coated tablets SPC (B01AF01 rivaroxaban)	Prescription only (POM)
Rivaroxaban Polpharma 20 mg film-coated tablets SPC (B01AF01 rivaroxaban)	Prescription only (POM)
Rivaroxaban Sandoz 10 mg film-coated tablets SPC (B01AF01 rivaroxaban)	Prescription only (POM)
Rivaroxaban Sandoz 15 mg film-coated tablets SPC (B01AF01 rivaroxaban)	Prescription only (POM)
Rivaroxaban Sandoz 2.5 mg film-coated tablets SPC (B01AF01 rivaroxaban)	Prescription only (POM)
Rivaroxaban Sandoz 20 mg film-coated tablets SPC (B01AF01 rivaroxaban)	Prescription only (POM)
Rivaroxaban Sun 15 mg film-coated tablets (B01AF01 rivaroxaban)	Prescription only (POM)
Rivaroxaban Sun 2.5 mg film-coated tablets (B01AF01 rivaroxaban)	Prescription only (POM)
Rivaroxaban Sun 20 mg film-coated tablets (B01AF01 rivaroxaban)	Prescription only (POM)
Rivaroxaban Tillomed 10 mg film-coated tablets SPC (B01AF01 rivaroxaban)	Prescription only (POM)
Rivaroxaban Tillomed 15 mg film coated tablets, Rivaroxaban Tillomed 20 mg film coated tablets SPC (B01AF01 rivaroxaban)	Prescription only (POM)
Rivaroxaban Torrent 2.5 mg film-coated tablets (B01AF01 rivaroxaban)	Prescription only (POM)
Rivaroxaban Umedica 10 mg film-coated tablets SPC (B01AF01 rivaroxaban)	Prescription only (POM)
Rivaroxaban Umedica 15 mg film-coated tablets SPC (B01AF01 rivaroxaban)	Prescription only (POM)
Rivaroxaban Umedica 2.5 mg film-coated tablets SPC (B01AF01 rivaroxaban)	Prescription only (POM)
Rivaroxaban Umedica 20 mg film-coated tablets (B01AF01 rivaroxaban)	Prescription only (POM)
Roteas SPC (B01AF03 edoxaban)	–
Throsaben 10 mg film-coated tablets SPC (B01AF01 rivaroxaban)	Prescription only (POM)

Other groups of the same level

B01AA Vitamin K antagonists 13 medicines
B01AB Heparin group antithrombotic drugs 81 medicines
B01AC Platelet aggregation inhibitors excl. heparin 168 medicines
B01AD Enzymes, antithrombotic 20 medicines
B01AE Direct thrombin inhibitors 32 medicines
B01AX Other antithrombotic agents 14 medicines

Other names of the ATC group

French: B01AF inhibiteurs directs du facteur Xa
German: B01AF Direkte Faktor-Xa-Inhibitoren
Spanish: B01AF Inhibidores directos del facto xa
German: B01AF Direkte Faktor-Xa-Inhibitoren
Italian: B01AF INIBITORI DIRETTI DEL FATTORE Xa
Turkish: B01AF Doğrudan faktör Xa inhibitörleri
Portuguese (Brazil): B01AF Inibidores do factor Xa directos
Czech: B01AF Přímé inhibitory faktoru Xa
Slovak: B01AF Priame inhibítory faktora Xa
German (Switzerland): B01AF Direkte Faktor-Xa-Inhibitoren
French (Switzerland): B01AF Inhibiteurs directs du facteur Xa
Italian (Switzerland): B01AF INIBITORI DIRETTI DEL FATTORE Xa
Dutch: B01AF Directe factor Xa-remmers
English (Canada): B01AF Direct factor Xa inhibitors

Sources

Patient leaflets and SPCs: the MHRA product information (products.mhra.gov.uk) and the European Medicines Agency (EMA)
Active substances, ATC codes and legal categories: the NHS Dictionary of Medicines and Devices (dm+d), NHS Business Services Authority
World Health Organization (WHO): ATC/DDD classification, group B01AF

Contains public sector information licensed under the Open Government Licence v3.0.

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