A04AA Serotonin (5HT3) antagonists, antiemetics and antinauseants

Place in the ATC classification

How to read ATC codes – what the levels mean and what a code does not tell you.

A Alimentary tract and metabolism drugs 1,624 medicines
1. A04 Antiemetics and antinauseants 88 medicines
  1. A04A Antiemetics and antinauseants 88 medicines
    1. A04AA Serotonin (5HT3) antagonists, antiemetics and antinauseants 59 medicines
      1. A04AA01 ondansetron 38 medicines
      2. A04AA02 granisetron 10 medicines
      3. A04AA05 palonosetron 8 medicines
      4. A04AA55 palonosetron, combinations 3 medicines

2 more subgroups have no medicine with a leaflet on this site.

Active substances in the group

Granisetron 10 medicines
Netupitant 3 medicines
Ondansetron 38 medicines
Palonosetron 11 medicines

Medicines in the group and its subgroups

Medicine	Legal category
Akynzeo 235 mg / 0.25 mg powder for concentrate for solution for infusion SPC (A04AA55 palonosetron, combinations)	Prescription only (POM)
Akynzeo 300 mg / 0.5 mg hard capsules SPC	Prescription only (POM)
Akynzeo 300 mg/0.5 mg hard Capules (A04AA55 palonosetron, combinations)	Prescription only (POM)
Aloxi SPC (A04AA05 palonosetron)	Prescription only (POM)
Aloxi 250 micrograms solution for injection SPC (A04AA05 palonosetron)	Prescription only (POM)
Aloxi 500 micrograms soft capsules SPC no longer supplied (A04AA05 palonosetron)	–
Ametron Melt 4 mg oral Lyophilisate SPC (A04AA01 ondansetron)	Prescription only (POM)
Ametron Melt 8 mg oral Lyophilisate SPC (A04AA01 ondansetron)	Prescription only (POM)
Granisetron 1 mg / 1 ml concentrate for solution for infusion or injection SPC (A04AA02 granisetron)	–
Granisetron 1 mg film-coated tablets SPC (A04AA02 granisetron)	Prescription only (POM)
Granisetron 1 mg tablets SPC (A04AA02 granisetron)	Prescription only (POM)
Granisetron 1 mg/ml concentrate for solution for injection or infusion SPC (A04AA02 granisetron)	–
Granisetron 1 mg/ml solution for injection SPC (A04AA02 granisetron)	–
Granisetron 2 mg film-coated tablets SPC not available (A04AA02 granisetron)	–
Granisetron 3 mg / 3 ml concentrate for solution for infusion or injection SPC (A04AA02 granisetron)	–
Kytril 2 mg film-coated tablets SPC no longer supplied (A04AA02 granisetron)	–
Ondansetron 2 mg / ml solution for injection SPC (A04AA01 ondansetron)	–
Ondansetron 2 mg / ml solution for injection or infusion SPC (A04AA01 ondansetron)	–
Ondansetron 2 mg / ml solution for injection/infusion SPC (A04AA01 ondansetron)	–
Ondansetron 2 mg\|ml solution for injection SPC (A04AA01 ondansetron)	Prescription only (POM)
Ondansetron 4 mg / 5 ml oral solution SPC (A04AA01 ondansetron)	Prescription only (POM)
Ondansetron 4 mg / 5 ml syrup SPC (A04AA01 ondansetron)	–
Ondansetron 4 mg film-coated tablets SPC (A04AA01 ondansetron)	Prescription only (POM)
Ondansetron 4 mg orodispersible tablets SPC (A04AA01 ondansetron)	Prescription only (POM)
Ondansetron 4 mg solution for injection/infusion in Pre-filled syringe SPC (A04AA01 ondansetron)	Prescription only (POM)
Ondansetron 4 mg tablets SPC (A04AA01 ondansetron)	Prescription only (POM)
Ondansetron 8 mg / 5 ml oral solution SPC (A04AA01 ondansetron)	Prescription only (POM)
Ondansetron 8 mg film-coated tablets SPC (A04AA01 ondansetron)	Prescription only (POM)
Ondansetron 8 mg orodispersible tablets SPC (A04AA01 ondansetron)	Prescription only (POM)
Ondansetron 8 mg solution for injection/infusion in Pre-filled syringe SPC (A04AA01 ondansetron)	Prescription only (POM)
Ondansetron 8 mg tablets SPC (A04AA01 ondansetron)	Prescription only (POM)
Ondansetron 8 mg/5 ml syrup SPC (A04AA01 ondansetron)	–
Ondansetron Enexi 2 mg/ml solution for injection/infusion SPC (A04AA01 ondansetron)	–
Ondansetron Kabi 0.08 mg/ml solution for infusion SPC (A04AA01 ondansetron)	–
Ondansetron Kabi 0.16 mg/ml solution for infusion SPC (A04AA01 ondansetron)	–
Ondansetron Kabi 2 mg / ml solution for injection SPC (A04AA01 ondansetron)	–
Ondansetron Medley 4 mg/5 ml oral solution SPC (A04AA01 ondansetron)	–
Ondansetron Steranco 4 mg /5 ml oral solution SPC (A04AA01 ondansetron)	–
Palonosetron 250 micrograms solution for injection SPC (A04AA05 palonosetron)	Prescription only (POM)
Palonosetron 250 micrograms solution for injection in Pre-filled syringe SPC (A04AA05 palonosetron)	Prescription only (POM)
Palonosetron Accord 250 micrograms solution for injection SPC (A04AA05 palonosetron)	Prescription only (POM)
Palonosetron Hospira SPC (A04AA05 palonosetron)	–
Palonosetron Hydrochloride 250 micrograms solution for injection SPC (A04AA05 palonosetron)	Prescription only (POM)
Sancuso SPC (A04AA02 granisetron)	Prescription only (POM)
Sancuso 3.1 mg / 24 hours transdermal patch SPC (A04AA02 granisetron)	Prescription only (POM)
Setofilm 4 mg orodispersible Films SPC (A04AA01 ondansetron)	Prescription only (POM)
Setofilm 4 mg orodispersible Films, Ondansetron 4 mg orodispersible Films (A04AA01 ondansetron)	Prescription only (POM)
Setofilm 8 mg orodispersible Films SPC (A04AA01 ondansetron)	Prescription only (POM)
Zofran 4 mg / 5 ml syrup no longer supplied (A04AA01 ondansetron)	–
Zofran 4 mg Melt (A04AA01 ondansetron)	Prescription only (POM)
Zofran 4 mg tablets (A04AA01 ondansetron)	Prescription only (POM)
Zofran 8 mg Melt (A04AA01 ondansetron)	Prescription only (POM)
Zofran 8 mg tablets (A04AA01 ondansetron)	Prescription only (POM)
Zofran Flexi-amp injection 2 mg / ml, Zofran injection 2 mg / ml SPC (A04AA01 ondansetron)	–
Zofran Melt 4 mg, Ondansetron 4 mg oral Lyophilisates (A04AA01 ondansetron)	Prescription only (POM)
Zofran suppositories 16 mg no longer supplied (A04AA01 ondansetron)	–
Zofran syrup 4 mg / 5 ml SPC no longer supplied (A04AA01 ondansetron)	–
Zofran tablets 4 mg SPC no longer supplied (A04AA01 ondansetron)	–
Zofran tablets 8 mg no longer supplied (A04AA01 ondansetron)	–

Other groups of the same level

A04AD Other antiemetics 29 medicines

Other names of the ATC group

Czech: A04AA Antagonisté serotoninových 5HT3 receptorů
French: A04AA antagonistes de la sérotonine (5ht3)
German: A04AA Serotonin-5HT3-Rezeptorantagonisten
Spanish: A04AA Antagonistas de la serotonina (antiemeticos)
German: A04AA Serotonin-5HT3-Rezeptorantagonisten
Italian: A04AA ANTAGONISTI DELLA SEROTONINA (5HT3)
Polish: A04AA Antagoniści receptora serotoninowego 5HT3
Turkish: A04AA Serotonin (5HT3) antagonistleri, antiemetikler ve bulantı gidericiler
Portuguese (Brazil): A04AA Antagonistas da serotonina (5HT3)
Slovak: A04AA Antagonisty sérotonínu (5HT3)
German (Switzerland): A04AA Serotonin-5HT3-Rezeptorantagonisten
French (Switzerland): A04AA Antagonistes de la sérotonine (5ht3)
Italian (Switzerland): A04AA Antagonisti della serotonina (5ht3)
Dutch: A04AA Serotonine(5HT3)-antagonisten, anti-emetica en middelen tegen misselijkheid
English (Canada): A04AA Serotonin (5HT3) antagonists, antiemetics and antinauseants

Sources

Patient leaflets and SPCs: the MHRA product information (products.mhra.gov.uk) and the European Medicines Agency (EMA)
Active substances, ATC codes and legal categories: the NHS Dictionary of Medicines and Devices (dm+d), NHS Business Services Authority
World Health Organization (WHO): ATC/DDD classification, group A04AA

Contains public sector information licensed under the Open Government Licence v3.0.

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