Patient leaflet - Sodium Chloride 0.9% w/v and Glucose 5% w/v IV infusion BP

1. What Sodium Chloride 0.9% w/v and Glucose 5% w/v

IV Infusion BP is and what it is used for

This medicine contains normal salt and glucose. It is given to you via a drip into your vein (intravenous infusion).

It will be given to you:

if you are lacking water
if you are lacking water and salt
if you have lost chloride
as a partial calorie source to meet your energy requirements. It may also be used to dilute or dissolve medicines that are to be given to you by a drip.

2. What you need to know before you use Sodium Chloride 0.9% w/v and Glucose 5% w/v IV Infusion BP

You will not be given Sodium Chloride 0.9% w/v and Glucose 5% w/v IV Infusion BP:

if you have excess water in your body tissues (hyperhydration)
if you have abnormally high levels of electrolytes in your body fluids and tissues due to loss of water (hypertonic dehydration)
if your blood has become too acidic (lactic acidosis)
if you have abnormally high blood sugar level that only responds to high insulin doses or intolerance to glucose
if you have water on the lungs or in your brain
if you have very high levels of sodium or chloride in your blood
if you have heart failure

Warnings and precautions

Talk to your doctor, pharmacist or nurse before using Sodium Chloride 0.9% w/v and Glucose 5% w/v IV Infusion BP.

Special care will be taken with this medicine if you suffer from any of the following:

high levels of sodium or chloride in your blood
disorders where you have to limit your sodium and fluid intake, such as
- heart failure
- swelling of the limbs
- high blood pressure
- pre-eclampsia (see section ‘pregnancy and breast-feeding’)
- severe kidney problems

If you suffer from acute stroke and too high blood sugar levels, your doctor will take special care with you: Your blood sugar level will be corrected before you receive this medicine.

If you have low levels of potassium in your blood, your doctor will take special care of you.

At the beginning and while you are given this medicine your water balance, salt levels (especially potassium), blood acidity and blood sugar levels will be monitored by your doctor. If you have very low levels of sodium in your blood your doctor will ensure that your blood sodium levels are not raised too fast.

Adequate supply of vitamins (in particular vitamin B1) will be ensured. If your child is receiving this medicine, your doctor will take special care of them.

Please note: If this solution is used to dilute or dissolve medicines that are to be given to you by a drip your doctor will take into account the safety information of the additive.

Other medicines and Sodium Chloride 0.9% w/v and Glucose 5% w/v IV Infusion BP

Tell your doctor if you are taking, have recently taken or might take any other medicines.

Your doctor will adjust your dosage if you receive medicines that make you retain sodium and fluid (e.g. corticosteroids or non-steroidal anti-inflammatory drugs) or affect how your body uses glucose (e.g. corticosteroids).

Pregnancy and breast-feeding

If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor, pharmacist or nurse for advice before you are given this medicine.

Pregnancy

Your doctor will give you this medicine only with caution and under monitoring of your blood glucose level. Special care will be taken if you have a specific disorder that may occur during pregnancy, called pre-eclampsia, with the following symptoms: high blood pressure, cramps, swelling.

Glucose-containing solutions may have harmful effects on newborns (low blood sugar levels) when given during labour or delivery. Breast-feeding

This medicine can be given while you are breast feeding.

Driving and using machines

This medicine has no or negligible influence on the ability to drive or use machines.

3. How to use Sodium Chloride 0.9% w/v and Glucose 5% w/v IV Infusion BP

The medicine will be administered to you by a drip into a vein.

Dosage

Adults

The amount of the medicine that you will be given will be determined by your doctor and will depend on your age, weight, clinical condition, the acidity of your blood and concomitant therapy. Thus your individual requirements of fluid, electrolytes and energy will be taken into account. The normal maximum dosage for an adult is 40 ml/kg body weight/day. The maximum infusion rate is 5 ml per kg body weight per hour. If you suffer from diarrhoea or vomiting, your doctor will decide if you need to receive more of this medicine.

Sodium Chloride 0.9% w/v and Glucose 5% w/v IV Infusion BP

Solution for Infusion

Sodium Chloride, Glucose

0006/445634/0725

B|BRAUN

Package leaflet: Information for the user

B. Braun Melsungen AG · 34209 Melsungen, Germany

Read all of this leaflet carefully before you start using this medicine because it contains important information for you.

Keep this leaflet. You may need to read it again.
If you have any further questions, ask your doctor, pharmacist or nurse.
This medicine has been prescribed for you. Do not pass it on to others. It may harm them, even if their signs of illness are the same as yours.
If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effect not listed in this leaflet. See section 4.
B|BRAUN B. Braun Melsungen AG
34209 Melsungen Germany

Children

Children will receive a reduced dosage dependent upon their age, weight and clinical condition. Thus the individual daily requirements of fluid, electrolytes and energy of your child will be taken into account. If your child suffers from diarrhoea or vomiting, your doctor will decide if they need to receive more of this medicine.

Elderly patients

Basically the same dosage as for adults applies. But your doctor will take caution if you are suffering from other diseases often seen with advanced age, for example heart failure or kidney failure. Other special patient groups

Special care will be taken if you have an impaired glucose tolerance (e.g. after surgery, severe injury, lack of oxygen, organ failure etc.). In those cases your blood glucose level will be monitored while you receive this solution.

If you use more Sodium Chloride 0.9% w/v and Glucose 5% w/v IV Infusion BP than you should

It is unlikely that this happens as your infusion will be controlled by a doctor, pharmacist or nurse.

Symptoms

An overdose may lead to excess fluid in the body, which will be followed by

increased skin tension
congestion of your blood
swelling
water on the lungs and in your brain
disorders of your salt and acid-base balance.

It may also lead to

high blood sugar values and glucose in your urine.

Treatment

Treatment will be determined by your doctor. It may include stopping of the infusion, supervision of blood salt level and administration of suitable medicines to treat the symptoms observed (e.g. diuretics, insulin). In extreme situations you may also need dialysis.

If you have any further questions on the use of this medicine, ask your doctor, pharmacist or nurse.

4. Possible side effects

Like all medicines, Sodium Chloride 0.9% w/v and Glucose 5% w/v IV Infusion BP can cause side effects although not everybody gets them. You may experience:

hypersensitivity reactions, including a serious allergic reaction, referred to as anaphylaxis (may possibly occur in patients who are allergic against corn)
pain and swelling at the site of infusion.

Reporting of side effects

If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Yellow Card Scheme at www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store.

By reporting side effects you can help provide more information on the safety of this medicine.

5. How to store Sodium Chloride 0.9% w/v and Glucose 5% w/v IV Infusion BP

Keep this medicine out of the sight and reach of children. Do not use this medicine after the expiry date which is stated on the label and the outer carton. The expiry date refers to the last day of that month.

This medicine is for single use only. After use discard container and any unused medicine.

Do not reconnect partially used containers.

This medicine does not require any special storage conditions. Do not use this medicine if you notice that the solution is not clear and not colourless or the container and its closure are damaged.

6. Contents of the pack and other information

What Sodium Chloride 0.9% w/v and Glucose 5% w/v IV Infusion BP contains

The active substances are sodium chloride and glucose. 1000 ml of the solution contain

Sodium chloride 9.0 g

Glucose 50.0 g (as glucose monohydrate 55.0 g) Electrolytes

Sodium 154 mmol/l

Chloride 154 mmol/l

The other ingredient is water for injections

Energy: 837 kJ/l 200 kcal/l

Theoretical osmolarity: 586 mOsm/l

Acidity (titration to pH 7.4): < 0.5 mmol/l

pH: 3.5 – 5.5

What Sodium Chloride 0.9% w/v and Glucose 5% w/v IV Infusion BP looks like and contents of the pack

It is a clear colourless sterile solution of sodium chloride and glucose in water.

It is supplied in

polyethylene plastic bottles; contents 500 ml or 1000 ml available in packs of

1 x 500 ml, 10 × 500 ml

1 x 1000 ml, 10 × 1000 ml

Marketing authorisation holder and Manufacturer

B. Braun Melsungen AG

Carl-Braun-Straße 1

34212 Melsungen, Germany

Tel: +49-(0)-5661-71-0

Fax: +49-(0)-5661-4567

Manufacturer

B. Braun Melsungen AG

Carl-Braun-Straße 1

34212 Melsungen, Germany

B. Braun Medical S.A.

Carretera de Terrassa 121

08191 Rubí, Barcelona, Spain

This leaflet was last revised in June 2025

The following information is only intended for health-care professionals:

Method of administration:

The solution should not be administered through the same infusion equipment simultaneously, before or after an administration of blood because of the possibility of pseudo-agglutination.

Hypertonic solutions should be administered in a large peripheral or central vein to diminish the risk of causing irritation.

To avoid risk of air embolism, all air must be expelled before starting a pressure infusion.

Dosage:

Partial coverage of energy requirements, i. e. substitution of the obligatory daily glucose requirements, is only possible with the maximum dose stated above.