Patient leaflet - Sildenafil 25 mg film-coated tablets
1. What Sildenafil tablet is and what it is used for
Sildenafil contains the active substance sildenafil which belongs to a group of medicines called phosphodiesterase type 5 (PDE 5) inhibitors. It works by helping to relax the blood vessels in your penis, allowing blood to flow into your penis when you get sexually excited. Sildenafil tablet will only help you to get an erection if you are sexually stimulated.
Sildenafil is a treatment for adult men with erectile dysfunction, sometimes known as impotence. This is when a man cannot get, or keep a hard, erect penis suitable for sexual activity.
2. What you need to know before you take Sildenafil tablet
Do not take Sildenafil tablet
If you are allergic to sildenafil or any of the other ingredients
of this medicine (listed in section 6).
You should not take sildenafil if you are taking medicines called nitrates as the combination of these medicines may lead to a dangerous fall in your blood pressure. Always tell your doctor or pharmacist or nurse if you are taking any of these medicines that are often used for the relief of angina pectoris (or "chest pain"). You should not take sildenafil if you are using any of the medicines known as nitric oxide donors such as amyl nitrite ("pop-pers") as the combination may also lead to a dangerous fall in your blood pressure.
Tell your doctor or pharmacist if you are already taking riociguat.
If you are taking medicines known as protease inhibitors, such as for the treatment of HIV, your doctor may start you on the lowest dose (25 mg) of Sildenafil tablet.
Some patients who take alpha-blocker therapy for the treatment of high blood pressure or prostate enlargement may experience dizziness or light-headedness which may be caused by low blood pressure upon sitting or standing up quickly. Certain patients have experienced these symptoms when taking sildenafil with alpha-blockers. This is most likely to happen within 4 hours after taking Sildenafil tablet. To reduce the chance that these symptoms might happen, you should be on a regular daily dose of your alpha-blocker before you start sildenafil. Your doctor may start you on a lower dose (25 mg) of sildenafil tablet.
Tell your doctor or pharmacist if you are taking medicines containing sacubitril/valsartan, used to treat heart failure.
If you are taking medicines called nitrates, as the
combination may lead to a dangerous fall in your blood pressure. Tell your doctor if you are taking any of these medicines which are often given for relief of angina pectoris (or "chest pain"). If you are not certain, ask your doctor or pharmacist.
If you are using any of the medicines known as nitric oxide
donors such as amyl nitrite ("poppers") as the combination may also lead to a potentially dangerous fall in your blood pressure.
If you are taking riociguat. This drug is used to treat
pulmonary arterial hypertension (i.e., high blood pressure in the lungs) and chronic thromboembolic pulmonary hypertension (i.e., high blood pressure in the lungs secondary to blood clots). PDE5 inhibitors, such as sildenafil have been shown to increase the hypotensive effects of this medicine. If you are taking riociguat or are unsure tell your doctor.
- If you have a severe heart or liver problem.
If you have recently had a stroke or a heart attack, or if you
have low blood pressure.
If you have certain rare inherited eye diseases (such as
retinitis pigmentosa).
If you have ever had loss of vision due to non-arteritic
anterior ischaemic optic neuropathy (NAION).
Sildenafil with food, drink and alcohol
Sildenafil tablet can be taken with or without food. However, you may find that Sildenafil tablet takes longer to start working if you take it with a heavy meal.
Drinking alcohol can temporarily impair your ability to get an erection. To get the maximum benefit from your medicine, you are advised not to drink excessive amounts of alcohol before taking Sildenafil tablet.
Pregnancy, breast feeding and fertility
Sildenafil is not indicated for use by women.
Driving and using machines
Sildenafil may cause dizziness and can affect vision. You should be aware of how you react to sildenafil before you drive or use machinery.
Sildenafil 25 mg, 50 mg and 100 mg film-coated tablets contain sodium
This medicine contains less than 1 mmol sodium (23 mg) per tablet, that is to say essentially ‘sodium-free’.
3. How to take Sildenafil tablet
Always take this medicine exactly as your doctor or pharmacist has told you. Check with your doctor or pharmacist if you are not sure. The recommended starting dose is 50 mg.
Warnings and precautions
Talk to your doctor, pharmacist or nurse before taking
Sildenafil tablet.
If you have sickle cell anaemia (an abnormality of red blood
cells), leukaemia (cancer of blood cells), multiple myeloma (cancer of bone marrow).
If you have a deformity of your penis or Peyronie's Disease. - If you have problems with your heart. Your doctor should
carefully check whether your heart can take the additional strain of having sex.
If you currently have a stomach ulcer, or a bleeding problem
(such as haemophilia).
If you experience sudden decrease or loss of vision, stop
taking Sildenafil tablet and contact your doctor immediately. - You should not use sildenafil with any other oral or local
treatments for erectile dysfunction.
You should not use sildenafil with treatments for pulmonary arterial hypertension (PAH) containing sildenafil or any other PDE5 inhibitors.
You should not take sildenafil if you do not have erectile dysfunction.
You should not take sildenafil if you are a woman. Special considerations for patients with kidney or liver problems. You should tell your doctor if you have kidney or liver problems. Your doctor may decide on a lower dose for you. Children and adolescents
Sildenafil should not be given to individuals under the age of 18. Other medicines and Sildenafil tablet
Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines.
Sildenafil film-coated tablets may interfere with some medicines, especially those used to treat chest pain. In the event
You should not take Sildenafil more than once a day.
Do not take Sildenafil film-coated tablets in combination with other sildenafil containing products including Sildenafil orodispersible tablets or Sildenafil orodispersible films. You should take Sildenafil tablet about one hour before you plan to have sex.
Swallow the tablet whole with a glass of water.
If you feel that the effect of sildenafil is too strong or too weak, talk to your doctor or pharmacist.
Sildenafil will only help you to get an erection if you are sexually stimulated. The amount of time sildenafil takes to work varies from person to person, but it normally takes between half an hour and one hour. You may find that sildenafil takes longer to work if you take it with a heavy meal.
If sildenafil does not help you to get an erection, or if your erection does not last long enough for you to complete sexual intercourse you should tell your doctor.
The tablet can be divided into equal halves for ease of swallowing but should not be used to divide the dose (applicable for Sildenafil 50 mg and 100 mg tablets).
If you take more Sildenafil than you should:
You may experience an increase in side effects and their severity. Doses above 100 mg do not increase the efficacy. You should not take more tablets than your doctor tells you to:
Contact your doctor if you take more tablets than you should. If you have any further questions on the use of this medicine, ask your doctor, pharmacist, or nurse.
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4. Possible side effects
Like all medicines, this medicine can cause side effects although not everybody gets them. The side effects reported in association with the use of sildenafil are usually mild to moderate and of a short duration.
If you experience any of the following serious side effects stop taking sildenafil and seek medical help immediately: • An allergic reaction -this occurs uncommonly (may affect
up to 1 in 100 people)
Symptoms include sudden wheeziness, difficulty in
breathing or dizziness, swelling of the eyelids, face, lips or throat.
If you have Chest pains - this occurs uncommonly: If this
occurs during or after intercourse
- Get in a semi-sitting position and try to relax - Do not use nitrates to treat your chest pain • Prolonged and sometimes painful erections - this occurs
rarely (may affect up to 1 in 1000 people) If you have an erection which lasts for more than 4 hours, you should contact a doctor immediately.
A sudden decrease or loss of vision - this occurs rarely • Serious skin reactions - this occurs rarely
Symptoms may include severe peeling and swelling of the skin, blistering of the mouth, genitals and around the eyes, fever.
- Seizures or fits - this occurs rarely
Other side effects:
Very common (may affect more than 1 in 10 people): • headache.
Common (may affect up to 1 in 10 people):
- nausea,
- facial flushing,
hot flush (symptoms include a sudden feeling of heat in your
upper body),
- indigestion,
effects on vision (including colour tinge to vision, light
sensitivity, blurred vision or reduced sharpness of vision), • stuffy nose,
- dizziness.
Uncommon (may affect up to 1 in 100 people) • vomiting,
- skin rash,
- bleeding at the back of the eye,
- eye irritation,
- bloodshot eyes/red eyes,
- eye pain,
- seeing flashes of light,
- visual brightness,
- light sensitivity,
- watery eyes,
- pounding or rapid heartbeat,
- high blood pressure,
- low blood pressure,
- muscle pain,
- feeling sleepy,
- reduced sense of touch,
- vertigo,
- ringing in the ears,
- dry mouth,
- blocked or stuffy sinuses,
inflammation of the lining of the nose (symptoms include
runny nose, sneezing and stuffy nose),
- upper abdominal pain,
gastro-oesophageal reflux disease (symptoms include
heartburn),
- presence of blood in urine,
- pain in the arms or legs,
- nosebleed,
- Feeling hot,
- feeling tired.
Rare (may affect up to 1 in 1000 people):
- fainting,
- stroke,
- heart attack,
- irregular heartbeat,
- feeling of tightening of the throat,
- numb mouth,
- bleeding at the back of the eye,
- double vision,
- reduced sharpness of vision,
- abnormal sensation in the eye,
- swelling of the eye or eyelid,
- small particles or spots in your vision,
- seeing halos around lights,
- dilation of the pupil of the eye,
- discolouration of the white of the eye,
- penile bleeding,
- presence of blood in semen,
- dry nose,
- swelling of the inside of the nose,
- feeling irritable,
- sudden decrease or loss of hearing,
temporary decreased blood flow to parts of the brain.
Product Name : Sildenafil Tablets
Printing Color : Black
From post-marketing experience cases of unstable angina (a heart condition) and sudden death have been reported rarely. Of note, most, but not all, of the men who experienced these side effects had heart problems before taking this medicine. It is not possible to determine whether these events were directly related to sildenafil.
Reporting of side effects
If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Yellow Card Scheme Website: www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store. By reporting side effects you can help provide more information on the safety of this medicine.
5. How to store Sildenafil
Keep this medicine out of the sight and reach of children. This medicine does not require any special storage conditions. Do not use Sildenafil tablets after the expiry date which is stated on the carton and blister after EXP. The expiry date refers to the last day of the month.
Do not throw away any medicines via wastewater or household waste. Ask your pharmacist how to throw away medicines you no longer use. These measures will help protect the environment.
6. Contents of the pack and other information
What Sildenafil tablet contains
The active substance is sildenafil. Each film-coated tablet contains 25/50/100 mg of sildenafil (as citrate salt). The other ingredients are:
- Tablet core: microcrystalline cellulose, calcium hydrogen phosphate (anhydrous), croscarmellose sodium, magnesium stearate.
- Tablet coating: polyvinyl alcohol, titanium dioxide (E171), macrogol, talc, indigo carmine aluminium lake (E132), hypromellose, triacetin.
What Sildenafil tablet looks like and contents of the pack
Sildenafil 25 mg film-coated tablet Blue coloured round, biconvex, film-coated tablets debossed with 124 on one side and J on the other side.
Sildenafil 50 mg film-coated tablet Blue coloured round, scored biconvex, film-coated tablets debossed with 125 on one side and J on the other side with the score line.
Sildenafil 100 mg film-coated tablet Blue coloured round, biconvex, scored film-coated tablets debossed with 126 on one side and J on the other side with the score line.
Sildenafil tablet is supplied in the following pack sizes: Sildenafil 25 mg film-coated tablets
PVC/Aluminium foil blisters in cartons of 1, 2, 4, 8, 12 or 24 tablets.
Sildenafil 50 mg film-coated tablets
PVC/Aluminium foil blisters in cartons of 2, 4, or 8 tablets.
Sildenafil 100 mg film-coated tablets
PVC/Aluminium foil blisters in cartons of 1, 2, 4, 8, 12 or 24 tablets.
Not all pack sizes may be marketed.
Marketing Authorisation Holder and Manufacturer
Marketing Authorisation Holder
Euro-Link Pharma Ltd
110 Butterfield, Great Marlings
Luton, Bedfordshire,
LU2 8DL, UK
MANUFACTURER
Ascenders Consulting Services Limited,
110 Butterfield, Great Marlings,
Luton, LU2 8DL, United Kingdom
This leaflet was last revised in August 2026.
For information in large print, audio CD or Braille, please telephone +44 1582 439706 or email info@euro-linkpharma.co.uk
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