Moxonidine 200 micrograms and 400 micrograms Film-coated Tablets – patient leaflet, side effects, dosage

1 What Moxonidine Tablets are and what they are used for

Moxonidine Tablets contains a medicine called moxonidine. This medicine belongs to a group of medicines called “anti-hypertensives”.

Moxonidine is used to treat high blood pressure (hypertension). It works by making your blood vessels relax and widen. This helps to lower your blood pressure.

2 What you need to know before you take Moxonidine Tablets

Do not take Moxonidine Tablets if:

• you are allergic (hypersensitive) to moxonidine or any of the other ingredients of moxonidine (listed in Section 6)
• you have a slow heart rate caused by a heart problem called “sick sinus syndrome” or “2nd or 3rd degree AV-block”
• you have heart failure
• you have serious kidney problems

Do not take Moxonidine Tablets if any of the above apply to you. If you are not sure, talk to your doctor or pharmacist before taking Moxonidine Tablets.

Warnings and precautions

Talk to your doctor or pharmacist before taking Moxonidine Tablets if:

• you have a heart problem called “1st degree AVblock”
• you have a severe heart problem such as angina or chest pain at rest
• you have kidney problems. Your doctor may need to adjust your dose

• If any of the above apply to you (or you are not sure), talk to your doctor or pharmacist before taking Moxonidine Tablets.

  Other medicines and Moxonidine Tablets

  Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines. This includes medicines obtained without a prescription, including herbal medicines. This is because Moxonidine can affect the way some other medicines work. Also some other medicines can affect the way Moxonidine works.

  In particular, tell your doctor or pharmacist if you are taking any of the following medicines:

  • other medicines to lower your blood pressure. Moxonidine may increase the effect of these medicines
  • medicines for depression such as imipramine or amitriptyline
  • tranquillisers, sedatives or sleeping tablets such as benzodiazepines
  • beta-blockers (see “If you stop taking Moxonidine Tablets” in Section 3)
  • Moxonidine is removed from your body by your kidneys through a process called “tubular excretion”. Other medicines removed from the kidneys in the same way could affect how Moxonidine works.

If any of the above apply to you (or you are not sure), talk to your doctor or pharmacist before taking Moxonidine Tablets.

Moxonidine Tablets with food, drink and alcohol

• You can take the tablets with or without food.
• Do not drink alcohol while you are taking Moxonidine Tablets. This is because Moxonidine may increase the effects of alcohol.

Pregnancy, breast-feeding and fertility

• Tell your doctor if you are pregnant or might become pregnant. Your doctor will normally advise you to stop taking Moxonidine Tablets. Your doctor will advise you to take another medicine instead of Moxonidine Tablets.
• Tell your doctor if you are breast-feeding or about to start breast-feeding. Moxonidine Tablets are not recommended for mothers who are breastfeeding. Your doctor may advise you to take another medicine if you want to breast-feed, or may ask you to stop breast-feeding.

Ask your doctor or pharmacist for advice before taking any medicine if you are pregnant or breastfeeding.

Driving and using machines

You may feel sleepy or dizzy while taking Moxonidine Tablets. If this happens, talk to your doctor before driving or using any tools or machines.

Moxonidine 200 micrograms and 400 micrograms Film-coated Tablets contain lactose

If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicinal product

3 How to take Moxonidine Tablets

Always take Moxonidine Tablets exactly as your doctor has told you. Check with your doctor or pharmacist if you are not sure.

Taking this medicine

• Swallow the tablets whole with a glass of water.
• Try to take your tablets around the same time each day. This will help you remember to take them.

For adults and the elderly:

The usual starting dose is 200 micrograms a day.

• Your doctor may increase this dose to up to 600 micrograms a day. You should not take more than 400 micrograms as a single dose or more than 600 micrograms in any one day.
• If your doctor has told you to take 600 micrograms a day, this should be split in two (300 micrograms in the morning and 300 micrograms in the evening).
• Your doctor may tell you to take a lower dose if you have kidney problems.

Use in children and adolescents

Moxonidine Tablets should not be given to children and adolescents under 18 years.

If you take more Moxonidine Tablets than you should

If you take more Moxonidine Tablets than you should, talk to a doctor or go to a hospital straight away.

Take the medicine pack with you. The following effects may happen: headache, feeling sleepy (somnolence, sedation), fall in blood pressure (hypotension), slow heart rate (bradycardia), feeling dizzy (vertigo), dry mouth, being sick (vomiting), feeling tired (fatigue), weakness and pain in your stomach (abdominal pain).

If you forget to take Moxonidine Tablets

• If you forget to take a dose, take it as soon as you remember it. However, if it is nearly time for the next dose, skip the missed dose.
• Do not take a double dose to make up for a forgotten dose.

If you stop taking Moxonidine Tablets

• Keep taking your Moxonidine Tablets until your doctor decides that you should stop.
• If you need to stop, your doctor will lower your dose slowly over a few weeks. If you are taking more than one medicine for high blood pressure (such as beta-blockers), your doctor will tell you which medicine to stop first. This is so that your body can adjust slowly to the change.

If you have any further questions on the use of this product, ask your doctor or pharmacist.

4. Possible side effects

Like all medicines, Moxonidine Tablets can cause side effects, although not everybody gets them. The following side effects may happen with this medicine:

Stop taking Moxonidine Tablets and see a doctor straight away if you notice any of the following serious side effects – you may need urgent medical treatment:

• swelling of the face, lips or mouth (angioedema). This is uncommon, affecting less than 1 in 100 people.

Other side effects include:

Very Common (affects more than 1 in 10 people)

• dry mouth.

Common (affects less than 1 in 10 people)

• back pain
• headache
• weakness (asthenia)
• feeling dizzy (vertigo)
• rash or itching (pruritus)
• difficulty sleeping (insomnia), feeling sleepy (somnolence)
• feeling sick (nausea), diarrhoea, being sick (vomiting), indigestion (dyspepsia).

Uncommon (affects less than 1 in 100 people)

• neck pain
• feeling nervous
• fainting (syncope)

• swelling (oedema)

  • ringing or noise in the ears (tinnitus)
  • unusually slow heartbeat (bradycardia)
  • low blood pressure, including low blood pressure when standing up.

Reporting of side effects

If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Yellow Card Scheme at: www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store. By reporting side effects you can help provide more information on the safety of this medicine.

5. How to store Moxonidine Tablets

Do not use Moxonidine Tablets after the expiry date which is stated on the carton and blister strips. The expiry date refers to the last day of that month.

Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.

6. Contents of the pack and other information

What Moxonidine Tablets contain

• Each film coated tablet contains 200 micrograms, or 400 micrograms of moxonidine as active substance.
• The other ingredients are lactose monohydrate, crospovidone (Type A), povidone (K-25), magnesium stearate, hypromellose (E464), titanium dioxide (E171, polyethylene glycol 6000 (E1521), talc (E553b) and red ferric oxide (E172)

What Moxonidine Tablets looks like and contents of the pack

The 200 microgram tablets are pale pink colored (approximately 6 mm) round biconvex film coated tablets debossed with MX2 on one side and plain on other side.

The 400 microgram tablets are Brick red coloured (approximately 6 mm) round shaped biconvex film coated tablets debossed with MX4 on one side and plain on another side.

Moxonidine tablets are packed in blister packs of 14, 28 or 84 tablets.

Not all pack sizes may be marketed.

Marketing Authorisation Holder

GLORAMP Pharma Consulting Limited

9 Alderson Close,

Aylesbury, Buckinghamshire,

HP19 8TA, United Kingdom

Manufacturer

LIQUIDSUN Pharma Ltd

Meadow Park Industrial estate,

Bourne road, Essendine,

Stamford, PE9 4LT, United Kingdom

This leaflet was last revised in June 2026.

Blind or partially sighted? Is this leaflet hard to see or read? Please contact the Marketing Authorisation Holder listed above to obtain the leaflet in a format suitable for you.