Patient leaflet - Moxonidine 300 mcg film-coated tablets
1. What Moxonidine tablets is and what it is used for
Moxonidine tablets contains a medicine called moxonidine.
This medicine belongs to a group of medicines called “anti-hypertensives”. Moxonidine is used to treat high blood pressure (hypertension). It works by making your blood vessels relax and widen. This helps to lower your blood pressure. You must talk to a doctor if you do not feel better or if you feel worse.
2. What you need to know before
taking Moxonidine tablets Do not take Moxonidine tablets:
- if you are allergic (hypersensitive) to moxonidine or any of the other ingredients of this medicine (listed in Section 6).
- if you have a slow heart rate caused by a heart problem called “sick sinus syndrome” or “2nd or 3rd degree AV-block”.
- if you have heart failure.
- if you have serious kidney problems. Do not take Moxonidine tablets if any of the above apply to you. If you are not sure, talk to your doctor, pharmacist or nurse before taking Moxonidine tablets.
Warnings and precautions
Talk to your doctor, pharmacist or nurse before taking Moxonidine tablets:
- if you have a heart problem called “1st degree AV-block”.
- if you have a severe heart problem such as angina or chest pain at rest.
- if you have kidney problems. Your doctor may need to adjust your dose.
If any of the above apply to you (or you are not sure), talk to your doctor, pharmacist or nurse before taking Moxonidine tablets. Other medicines and Moxonidine tablets
Tell your doctor, pharmacist or nurse if you are taking, have recently taken or might take any other medicines. This includes medicines obtained without a prescription, including herbal medicines. This is because Moxonidine tablets can affect the way some other medicines work. Also some
other medicines can affect the way Moxonidine tablets works.
In particular, tell your doctor, pharmacist or nurse if you are taking any of the following medicines:
- other medicines to lower your blood pressure. Moxonidine tablets may increase the effect of these medicines
- medicines for depression such as imipramine or amitriptyline
- tranquillisers, sedatives or sleeping tablets such as benzodiazepines
- beta-blockers (see “If you stop taking Moxonidine tablets” in Section 3)
- Moxonidine tablets is removed from your body by your kidneys through a process called “tubular excretion”. Other medicines removed from the kidneys in the same way could affect how Moxonidine tablets works.
If any of the above apply to you (or you are not sure), talk to your doctor, pharmacist or nurse before taking Moxonidine tablets. Moxonidine tablets with food, drink and alcohol
- You can take the tablets with or without food.
- Do not drink alcohol while you are taking Moxonidine tablets. This is because Moxonidine tablets may increase the effects of alcohol.
Pregnancy and breast-feeding
- Tell your doctor if you are pregnant or might become pregnant. Your doctor will normally advise you to stop taking Moxonidine tablets. Your doctor will advise you to take another medicine instead of Moxonidine tablets.
- Tell your doctor if you are breast-feeding or about to start breast-feeding. Moxonidine tablets is not recommended for mothers who are breastfeeding. Your doctor may advise you to take another medicine if you want to breast-feed, or may ask you to stop breast-feeding.
- Ask your doctor, pharmacist or nurse for advice before taking any medicine if you are pregnant or breastfeeding.
Driving and using machines
You may feel sleepy or dizzy while taking Moxonidine tablets. If this happens, talk to your doctor before driving or using any tools or machines.
Moxonidine tablets contains lactose
If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicinal product.
3. How to take Moxonidine tablets
Always take Moxonidine tablets exactly as your doctor has told you. Check with your doctor, pharmacist or nurse if you are not sure.
Taking this medicine
- Swallow the tablets whole with a glass of water.
- Try to take your tablets around the same time each day. This will help you remember to take them.
The recommended dose is:
The usual starting dose is 200 micrograms a day.
- Your doctor may increase this dose to up to 600 micrograms a day. You should not take more than 400 micrograms as a single dose or more than 600 micrograms in any one day.
- If your doctor has told you to take 600 micrograms a day, this should be split in two (300 micrograms in the morning and 300 micrograms in the evening).
Your doctor may tell you to take a lower dose if you have kidney problems. Moxonidine 200mcg Film-coated Tablets Moxonidine 300mcg Film-coated Tablets Moxonidine 400mcg Film-coated Tablets
P3209T
| Product: | Moxonidine Film-coated Tablets |
| P3209T | |
| 140 x 310 mm | |
| 9pt | |
| 10/02/25 | |
| 2 | |
| Amendment Date | 25/02/26 |
Use in children and adolescents
Moxonidine tablets should not be given to children and adolescents under 18 years. If you take more Moxonidine tablets than you should
If you take more Moxonidine tablets than you should, talk to a doctor or go to a hospital straight away. Take the medicine pack with you. The following effects may happen: headache, feeling sleepy (somnolence, sedation), fall in blood pressure (hypotension), slow heart rate (bradycardia), feeling dizzy (vertigo), dry mouth, being sick (vomiting), feeling tired (fatigue), weakness and pain in your stomach (abdominal pain).
If you forget to take Moxonidine tablets
- If you forget to take a dose, take it as soon as you remember it. However, if it is nearly time for the next dose, skip the missed dose.
- Do not take a double dose to make up for a forgotten dose.
If you stop taking Moxonidine tablets
- Keep taking your tablets until your doctor decides that you should stop.
If you need to stop, your doctor will lower your dose slowly over a few weeks. If you are taking more than one medicine for high blood pressure (such as
beta-blockers), your doctor will tell you which medicine to stop first. This is so that your body can adjust slowly to the change
If you have any further questions on the use of this medicine, ask your doctor, pharmacist or nurse.
4. Possible side effects
Like all medicines, this medicine can cause side effects, although not everybody gets them. The following side effects may happen with this medicine:
Stop taking Moxonidine tablets and see a doctor straight away if you notice any of the following serious side effects – you may need urgent medical treatment:
- swelling of the face, lips or mouth (angioedema).
This is uncommon, affecting less than 1 in 100 people.
Other side effects include:
Very Common (affects more than 1 in 10 people)
- dry mouth.
Common (affects less than
1 in 10 people)
- back pain
- headache
- weakness (asthenia)
- feeling dizzy (vertigo)
- rash or itching (pruritus)
- difficulty sleeping (insomnia), feeling sleepy (somnolence)
- feeling sick (nausea), diarrhoea, being sick (vomiting), indigestion (dyspepsia). Uncommon (affects less than
1 in 100 people)
- neck pain
- feeling nervous
- fainting (syncope)
- swelling (oedema)
- ringing or noise in the ears (tinnitus)
- unusually slow heartbeat (bradycardia)
- low blood pressure, including low blood pressure when standing up.
Reporting of side effects
If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Yellow Card Scheme at: www.mhra.gov.uk/yellowcard or search for
MHRA Yellow Card in the Google Play or Apple App Store. By reporting side effects, you can help provide more information on the safety of this medicine.
5. How to store Moxonidine tablets
- Keep this medicine out of the sight and reach of children.
- Do not use this medicine after the expiry date which is stated on the label and carton. The expiry date refers to the last day of that month.
- This medicinal product does not require any special storage conditions.
- Do not use this medicine if you notice any visible signs of deterioration.
- Do not throw away any medicines via wastewater or household waste. Ask your pharmacist how to throw away medicines you no longer use. These measures will help protect the environment.
6. Contents of the pack and other information
What Moxonidine tablets contains
- The active ingredient is moxonidine: Each film-coated tablet contains 200 micrograms, 300 micrograms or 400 micrograms of moxonidine.
The other ingredients are:
Tablet core: lactose monohydrate, crospovidone, hydroxypropyl cellulose, magnesium stearate
Tablet coating: hypromellose (E464), titanium dioxide (E171), macrogol (E1521), iron oxide red (E172), talc (E553b), glycerol (E422).
What Moxonidine tablets looks like and contents of the pack
200mcg: Pale pink colour, round shaped, film-coated tablets, debossed with 'L' on one side and '18' on other side.
300mcg: Pale red colour, round shaped, film-coated tablets, debossed with 'L' on one side and '19' on other side.
400mcg: Dull red colour, round shaped, film-coated tablets, debossed with ‘L’ on side and ‘20’ on other side.
Moxonidine tablets are available in packs of 14, 28 or 84 tablets. Not all pack sizes may be marketed.
Marketing Authorisation Holder and Manufacturer
Marketing Authorisation Holder
Crescent Pharma Ltd., Key House, Sarum Hill, Basingstoke, RG21 8SR, UK. Telephone: 01256 772 730
Email: Safety@crescentpharma.com Manufacturer: Noumed Life Sciences Ltd., Noumed House, Shoppenhangers Road, Maidenhead, Berkshire, SL6 2RB, UK. This leaflet was last revised in February 2026.
Other sources of information:
To listen to or request a copy of this leaflet in braille, large print or audio please call, as above (UK only) Please be ready to give the following information: Product name: Moxonidine 200mcg Film-coated Tablets Reference number: PL 20416/0920 Product name: Moxonidine 300mcg Film-coated Tablets Reference number: PL 20416/0921 Product name: Moxonidine 400mcg Film-coated Tablets Reference number: PL 20416/0922