Patient leaflet - Ibuprofen tablets BP 600 mg
1. What Ibuprofen Tablets are and what they are used for
- Zidovudine (an anti-viral drug)
- Drugs such as ciclosporin or tacrolimus (to
These tablets contain the active ingredient Ibuprofen, which is one of the group of medicines called Non-Steroidal Anti-Inflammatory Drugs (known as NSAIDs) which work by changing the body's response to pain, swelling and high temperatures.
prevent rejection following organ or bone marrow transplants)
- Mifepristone (to terminate a pregnancy)
A quinolone antibiotic for treating infection
(e.g. ciprofloxacin, ofloxacin)
Other special warnings
They can be used to relieve pain and inflammation in conditions such as osteoarthritis, rheumatoid arthritis (including juvenile rheumatoid arthritis or Still's disease), arthritis of the spine, ankylosing spondylitis, swollen joints, frozen shoulder, bursitis, tendinitis, tenosynovitis, lower back pain, sprains and strains.
Medicines such as Ibuprofen may be associated with a small increased risk of heart attack ("myocardial infarction") or stroke. Any risk is more likely with high doses and prolonged treatment. Do not exceed the recommended dose or duration of treatment.
You should discuss your treatment with your doctor or pharmacist before taking Ibuprofen Tablets if you:
Ibuprofen Tablets can also be used for other painful conditions such as period pain, dental pain, headache including migraine and pain following surgery.
have heart problems including heart failure,
angina (chest pain) or you have had a heart attack, bypass surgery or peripheral artery disease (poor circulation in the legs or feet due to narrow or blocked arteries).
2. What you need to know before you take Ibuprofen Tablets
- have any kind of stroke or think that you might
Do not take Ibuprofen Tablets if:
be at risk of these conditions (e.g. if you have a family history of heart disease or stroke, high blood pressure, diabetes, high cholesterol or are a smoker).
you are allergic to Ibuprofen or any other
non-steroidal anti-inflammatory drugs (NSAIDs), aspirin or to any of the other ingredients in the tablets (see section 6) (An allergic reaction may be recognised as
have systemic lupus erythematosus (SLE,
sometimes known as lupus) or a connective tissue disease (autoimmune diseases affecting connective tissue).
shortness of breath, blocked nose, rash, itching, swollen face or lips)
There is a risk of kidney damage in dehydrated children and adolescents. Ibuprofen may make it more difficult to become pregnant. You should inform your doctor if you are planning to become pregnant or if you have problems becoming pregnant.
you have a peptic ulcer (ulcer in your stomach
or duodenum) or bleeding in your stomach, or have had two or more episodes of peptic ulcers, stomach bleeding or perforation in the past
you have ever had stomach bleeding or
perforation caused by taking NSAID painkillers
you have a condition which increases your
Alcohol: Ibuprofen may cause some side effects including dizziness, drowsiness and stomach problems such as bleeding in the stomach. Drinking excessive alcohol with ibuprofen tablet might make these side effects worse.
tendency to bleeding
- you have severe heart, liver or kidney failure
- you are in the last 3 months of pregnancy.
Warnings and precautions
Talk to your doctor, pharmacist or nurse before taking Ibuprofen Tablets, if:
Pregnancy, breast-feeding and fertility
If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.
- you have or have ever suffered from asthma
- you suffer from heart, liver or kidney problems
- you have high blood pressure
you suffer from a bleeding disorder
The use of Ibuprofen whilst pregnant or breast-feeding should be avoided. Ibuprofen should not be used in the last 3 months of pregnancy and should only be taken in the first 6 months of pregnancy on the advice of your doctor. The use of Ibuprofen may impair female fertility and is not recommended in women attempting to conceive.
you suffer from systemic lupus erythematosus
(SLE) or another connective tissue disorder
you have a history of stomach or intestinal
problems (such as Crohn's disease or colitis)
you are elderly, as you may be more likely to
suffer from side effects
you are in the first 6 months of pregnancy or
you are breast-feeding
you suffer from swelling and irritation inside
If you are taking Ibuprofen Tablets for longer than the recommended time or at higher than recommended doses you are at risk of serious harms. These include serious harms to the stomach/gut and kidneys, as well as very low levels of potassium in your blood. These can be fatal (see section 4).
the nose
- you have chicken pox or shingles.
you have been diagnosed with medication
overuse headache (MOH) despite regular use of analgesics
you have an infection - please see heading
“Infections” below.
Driving and using machines
Skin reactions
Ibuprofen Tablets may make you feel dizzy, tired, drowsy or might affect your vision. If you think this medicine has affected you do not drive or operate machinery.
Serious skin reactions including exfoliative dermatitis, erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis, drug reaction with eosinophilia and systemic symptoms (DRESS), acute generalized exanthematous pustulosis (AGEP) have been reported in association with ibuprofen treatment. Stop using Ibuprofen Tablets and seek medical attention immediately if you notice any of the symptoms related to these serious skin reactions described in section 4.
Ibuprofen Tablets contain Sunset Yellow
May cause allergic reactions.
3. How to take Ibuprofen Tablets
Always take this medicine exactly as your doctor or pharmacist has told you. Check with your doctor or pharmacist if you are not sure.
Signs of an allergic reaction to this medicine, including breathing problems, swelling of the face and neck region (angioedema), chest pain have been reported with ibuprofen. Stop immediately Ibuprofen Tablets and contact immediately your doctor or medical emergencies if you notice any of these signs.
The tablets should be swallowed with a drink of water with or after a meal or a snack. Ibuprofen Tablets should be swallowed whole and not chewed, broken, crushed or sucked to help prevent discomfort in the mouth or irritation in the throat.
The normal dose will be different for different medical conditions and patients.
Infections
The lowest effective dose should be used for the shortest duration necessary to relieve symptoms. If you have an infection, consult a doctor without delay if symptoms (such as fever and pain) persist or worsen (see section 2).
Ibuprofen Tablets may hide signs of infections such as fever and pain. It is therefore possible that Ibuprofen Tablets may delay appropriate treatment of infection, which may lead to an increased risk of complications. This has been observed in pneumonia caused by bacteria and bacterial skin infections related to chickenpox. If you take this medicine while you have an infection and your symptoms of the infection persist or worsen, consult a doctor without delay.
Adults and children over 12 years:
Initial dose: 2 to 3 tablets in divided doses. The maximum dose per day is 4 tablets.
Maintenance dose: 1 to 2 tablets in divided doses. In cases of severe juvenile arthritis your doctor may increase the dosage up to 40 mg/kg in divided doses.
Other medicines and Ibuprofen Tablets
Elderly:
Caution should be exercised in older patients. Your doctor will decide the dose that is best for you. The pharmacist's label will also tell you how many tablets to take and how often. If you are not sure about anything, ask your doctor or pharmacist. These tablets should not be given to children under the age of 12 years. You should avoid excessive use of painkillers. If you usually take painkillers, especially combinations of different painkillers, you may damage your kidneys, tell your doctor if you are already taking another painkiller before taking this medicine and your doctor will decide whether you should take this medicine. This risk may be increased if you are dehydrated.
If you take more Ibuprofen Tablets than you should
If you have taken more Ibuprofen Tablets than you should, or if children have taken medicine by accident always contact a doctor or nearest hospital to get an opinion of the risk and advice on action to be taken. The symptoms can include nausea, stomach pain, vomiting (may be blood streaked), headache, ringing in the ears, confusion and shaky eye movement. At high doses, drowsiness, chest pain, palpitations, loss of consciousness, convulsions (mainly in children), weakness and dizziness, blood in urine, cold body feeling and breathing problems have been reported.
If you forget to take Ibuprofen Tablets
Do not take a double dose to make up for a forgotten dose. Take it as soon as possible. However, if it is almost time for the next dose, skip the missed dose and continue with the regular dosing schedule.
If you stop using Ibuprofen Tablets
Please speak to your doctor or pharmacist before stopping this or any medicine.
If you have any further questions on the use of this medicine, ask your doctor, pharmacist or nurse.
4. Possible side effects
Like all medicines, this medicine can cause side effects, although they are usually mild and not everybody gets them.
If any side effects become serious or if you notice any side effects that are not listed in this leaflet, please tell your doctor or pharmacist. You can minimise the risk of side effects by taking the least amount of tablets for the shortest amount of time necessary to control your symptoms.
STOP TAKING Ibuprofen Tablets and seek immediate medical help if you experience:
Signs of aseptic meningitis such as severe
headache, high temperature, stiffness of the neck or intolerance to bright light.
Signs of intestinal bleeding such as
Passing blood in your faeces
(stools/motions)
- Passing black tarry stools
Vomiting any blood or dark particles that
look like coffee grounds.
- Liver, Kidney problems or difficulty urinating. Ibuprofen Tablets, especially when taken at higher than recommended doses or for a prolonged period of time, can cause damage to your kidneys and affect them removing acids properly from your blood into the urine (renal tubular acidosis). It can also cause very low levels of potassium in your blood (see section 2). This is a very serious condition and will require immediate treatment. Signs and symptoms include muscle weakness and light-headedness.
Chest pain, which can be a sign of a potentially
serious allergic reaction called Kounis syndrome
Reddish non-elevated, target-like or circular
patches on the trunk, often with central blisters, skin peeling, ulcers of mouth, throat, nose, genitals and eyes. These serious skin rashes can be preceded by fever and flu-like symptoms [exfoliative dermatitis, erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis].
Widespread rash, high body temperature and
enlarged lymph nodes (DRESS syndrome).
A red, scaly widespread rash with bumps under
the skin and blisters accompanied by fever. The symptoms usually appear at the initiation of treatment (acute generalised exanthematous pustulosis).
Tell your doctor and stop taking Ibuprofen Tablets if you experience:
Unexplained stomach pain (abdominal pain) or
other abnormal stomach symptoms, indigestion, heartburn, feeling sick and/or vomiting.
Unexplained wheezing, shortness of breath,
skin rash, itching or bruising (these may be symptoms of an allergic reaction).
- Yellowing of the eyes and/or skin (Jaundice).
Severe sore throat with high fever (these may
be symptoms of a condition known as agranulocytosis).
Loss of vision, Blurred or disturbed vision
(visual impairment) or seeing/hearing strange things (hallucinations).
Fluid retention e.g. swollen ankles (this may
be a sign of kidney problems).
Severe spreading skin rash (Stevens-Johnson
Syndrome, toxic epidermal necrolysis and erythema multiforme, symptoms include severe skin rash, blistering of skin, including inside mouth, nose, and genitals, as well as skin peeling which may be accompanied with symptoms such as aching, headaches, and feverishness).
Medicines such as Ibuprofen Tablets may be associated with a small increased risk of high blood pressure, heart attack ("myocardial infarction") or stroke or heart failure.
Medicines such as Ibuprofen Tablets have in exceptional cases been associated with severe skin problems for patients with chickenpox or shingles.
Blood disorders such as reduction in blood cells and platelet counts - the first signs are: high temperature, sore throat, mouth ulcers, flu-like symptoms, bleeding from the mouth, nose, ear and the skin. Kidney problems such as reduced kidney function, fluid retention (oedema), inflammation of the kidney and kidney failure. Liver problems such as inflammation of the liver, reduced liver function and yellowing of the eyes and/or skin (jaundice) or severe skin reactions may occur rarely with Ibuprofen.
Ibuprofen has also been shown to sometimes worsen the symptoms of Crohn's disease or colitis.
Other side effects
Common (may affect up to 1 in 10 people):
- rash
- feeling dizzy or tired
- diarrhoea, being sick, wind, constipation
- headache - if this happens while you are taking this medicine it is important not to take any other medicines for pain to help with this.
Uncommon (may affect up to 1 in 100 people):
- feeling drowsy
- feeling anxious
- feeling a tingling sensation or 'pins and needles'
- difficulty sleeping
- hives
- itching
- visual disturbances, hearing problems
- hepatitis, yellowing of your skin or eyes, reduced liver function
- reduced kidney function, inflammation of the kidneys, kidney failure
- sneezing, blocked, itchy or runny nose (rhinitis)
- stomach or gut ulcer, hole in the wall of the digestive tract
- inflammation of your stomach lining
- small bruises on your skin or inside your mouth, nose or ears
- difficulty breathing, wheezing or coughing
- asthma or worsening of asthma
- ringing in ears (tinnitus)
- sensation of feeling dizzy or spinning (vertigo)
- mouth ulcers.
Rare (may affect up to 1 in 1,000 people):
- feeling depressed or confused
Very rare (may affect up to 1 in 10,000 people):
- liver failure
- heart failure
- heart attack
- inflammation of the pancreas.
Not known (frequency cannot be estimated from available data):
Worsening of ulcerative colitis or Crohn's
Disease (inflammation of the colon)
- A severe skin reaction known as DRESS syndrome can occur. Symptoms of DRESS include: skin rash, fever, swelling of lymph nodes and an increase of eosinophils (a type of white blood cells)
- A red, scaly widespread rash with bumps under the skin and blisters mainly localized on the skin folds, trunk and upper extremities accompanied by fever at the initiation of treatment (acute generalised exanthematous pustulosis). Stop using Ibuprofen Tablets if you develop these symptoms and seek medical attention immediately. See also section 2.
- Skin becomes sensitive to light.
Reporting of side effects
If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Yellow Card Scheme at: www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store. By reporting side effects you can help provide more information on the safety of this medicine.
5. How to store Ibuprofen Tablets
Keep this medicine out of the sight and reach of children.
Keep this medicine in the pack provided and protect from heat, light and moisture.
Your tablets should be stored below 25°C. Do not use this medicine after the expiry date which is stated on the pack. The expiry date refers to the last day of that month.
Do not throw away any medicines via wastewater or household waste. Ask your pharmacist how to throw away medicines you no longer use. These measures will help protect the environment. If your doctor decides to stop your treatment, return any leftover tablets to your pharmacist. Only keep the tablets if your doctor tells you to.
6. Contents of the pack and other information
What Ibuprofen Tablets contain:
Ingredients
Ibuprofen Tablets 600 mg contain 600 mg of Ibuprofen as the active ingredient.
The other ingredients are: Colloidal silicon dioxide, maize starch, pregelatinised maize starch, sodium starch glycolate, stearic acid, hypromellose, hydroxypropyl cellulose, macrogol, erythrosine (E127), titanium dioxide (E171) and sunset yellow (E110).
What the Ibuprofen Tablets look like and contents of the pack:
Ibuprofen Tablets are oblong, pink film-coated tablets. Each pack contains 28, 42, 50, 56, 84, 100, 112, 250, 500 or 1000 tablets.
Not all pack sizes may be marketed.
Marketing Authorisation Holder and Manufacturer
Relonchem Limited,
Cheshire House, Gorsey Lane, Widnes, Cheshire, WA8 0RP, UK.
Product License No.: PL 20395/0132.
This leaflet was last revised in May 2026.
If you would like this leaflet in a different format please contact the license holder at the above address.
VERSION XXXXXX DATE 21.05.2026 150 mm
2.3
NO. OF COLORS 01
150 mm
PRODUCT NAME
Ibuprofen Tablets
██ Black
PRODUCT LICENCE NO.
PL 20395-0132
██ Dieline
PIL
COUNTRY
UK (English)
STRENGTH
PACK SIZE
150 x 550 mm
600 mg
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MANUFACTURER
SOFTWARE
ARTIST
Marksans (North) Adobe illustrator CC Bhuddish
FONT & SIZE
Arial (Min 9 pt)
REMARKS
NA
REASON FOR CHANGE
Comments received from Chaithra on 21.05.2026.