Patient leaflet - Anadin Joint Pain 200 mg tablets
1. What your medicine is and what it is used for
Each tablet contains: 200mg of ibuprofen.
Ibuprofen belongs to a group of medicines called Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) that work by relieving pain and reducing inflammation, swelling and fever.
Your medicine is for effective relief from: Joint and muscular pain, stiffness, backache and neuralgia.
2. Before you take your medicine
Do not give to children under 12 years.
Do not take if you:
- have or have ever had a stomach ulcer, perforation or bleeding, including due to NSAIDs.
- are allergic to ibuprofen or any other ingredient of the product, aspirin or other related painkillers.
- suffer from severe liver, kidney or heart failure.
are in the last 3 months of pregnancy.
Warning and Precautions
If you are taking Anadin Joint Pain for longer than the recommended time or at higher than recommended doses you are at risk of serious harms. These include serious harms to the stomach/gut and kidneys, as well as very low levels of potassium in your blood. These can be fatal (see section 4).
Anti-inflammatory/pain-killer medicines like ibuprofen may be associated with a small increased risk of heart attack or stroke, particularly when used at high doses. Do not exceed the recommended dose or duration of treatment. Signs of an allergic reaction to this medicine, including breathing problems, swelling of the face and neck region (angioedema), chest pain have been reported with ibuprofen. Stop using Anadin Joint Pain immediately and contact your doctor or medical emergencies if you notice any of these signs.
Take special care and talk to a pharmacist or your doctor before taking this medicine if you have or are:
- heart problems including heart failure, angina (chest pain), or if you have had a heart attack, bypass surgery, peripheral artery disease (poor circulation in the legs or feet due to narrow or blocked arteries), or any kind of stroke (including ‘mini-stroke’ or transient ischaemic attack “TIA”). • high blood pressure, diabetes, high cholesterol, have a family history of heart disease or stroke, or if you are a smoker. • asthmatic or suffer from kidney, liver or bowel problems, or from hayfever.
- suffering from Systemic Lupus Erythematosus (SLE) a condition of the immune system affecting connective tissue resulting in joint pain, skin change and disorders of other organs.
- trying to become pregnant (ibuprofen belongs to a group of medicines (NSAIDs) which may impair fertility in women. This effect is reversible upon stopping the medicine. It is unlikely that ibuprofen, used occasionally will affect your chances of becoming pregnant, however, tell your doctor before taking this medicine, if you have problems becoming pregnant).
- in the first 6 months of pregnancy.
- 12-18 years old as there is a risk of renal impairment. Therefore ask a doctor before use if you are a 12-18 year old who has not been drinking fluids or has lost fluids due to continuous vomiting or diarrhoea.
- an infection - please see heading “Infections” below.
Skin reactions
Serious skin reactions have been reported in association with Anadin Joint Pain treatment. You should stop taking Anadin Joint Pain and seek medical attention immediately, if you develop any skin rash, lesions of the mucous membranes, blisters or other signs of allergy since this can be the first signs of a very serious skin reaction. See section 4.
Infections
Anadin Joint Pain 200mg Tablets may hide signs of infections such as fever and pain. It is therefore possible that Anadin Joint Pain 200mg Tablets may delay appropriate treatment of infection, which may lead to an increased risk of complications. This has been observed in pneumonia caused by bacteria and bacterial skin infections related to chickenpox. If you take this medicine while you have an infection and your symptoms of the infection persist or worsen, consult a doctor without delay.
Taking Other Medicines
Do not use the medicine if you are:
- taking other NSAID painkillers, or aspirin with a daily dose above 75mg.
Anadin Joint Pain 200mg Tablets may affect or be affected by some other medicines. Talk to your doctor or pharmacist if you are taking: • medicines that are anti-coagulants (i.e. thin blood/prevent clotting e.g. aspirin/acetylsalicylic acid, warfarin, ticlopidine). • medicines that reduce high blood pressure (ACE-inhibitors such as captopril, beta-blockers such as atenolol, angiotensin-II receptor antagonists such as losartan).
- medicines such as corticosteroids, antiplatelet agents, cardiac glycosides, selective serotonin reuptake inhibitors, lithium, methotrexate, ciclosporin, mifepristone, tacrolimus, zidovudine, or quinolone antibiotics.
Some other medicines may affect or be affected by the treatment of Anadin Joint Pain 200mg Tablets. You should therefore always seek the advice of your doctor or pharmacist before you use Anadin Joint Pain 200mg Tablets with other medicines. Important information about some of the ingredients of your medicine
If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicine as it contains sucrose. Propylparahydroxybenzoate and methylparahydroxybenzoate may cause allergic reactions (possibly delayed). Pregnancy, breast-feeding and fertility
You should not take Anadin Joint Pain during the first 6 months of pregnancy unless absolutely necessary and advised by your doctor. If you need treatment during this period or while you are trying to get pregnant, the lowest dose for the shortest time possible should be used. If taken for more than a few days from 20 weeks of pregnancy onward, Anadin Joint Pain can cause kidney problems in your unborn baby that may lead to low levels of amniotic fluid that surrounds the baby (oligohydramnios) or narrowing of a blood vessel (ductus arteriosus) in the heart of the baby. If you need treatment for longer than a few days, your doctor may recommend additional monitoring. Do not take Anadin Joint Pain if you are in the last 3 months of pregnancy as it could harm your unborn child or cause problems at delivery. It can cause kidney and heart problems in your unborn baby. It may affect your and your baby’s tendency to bleed and cause labour to be later or longer than expected.
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3. How to take your medicine
For oral administration and short term use only.
Dosage: Adults, the elderly, and children and adolescents over 12 year of age: The minimum effective dose should be used for the shortest time necessary to relieve symptoms. 1 or 2 tablets up to 3 times a day, as required.
When 2 tablets are taken, pain relief can last for up to 8 hours. Take only as much as you need and leave at least 4 hours between each dose. Do not take more than 6 tablets in any 24 hour period.
Do not give to children under 12 years.
If you are aged between 12 and 18 years and the product is required for more than 3 days or if the symptoms worsen, you should contact your doctor.
If you are 18 years or older you should not take this product for longer than 10 days unless your doctor tells you to. If symptoms persist or worsen consult a pharmacist or your doctor. The lowest effective dose should be used for the shortest duration necessary to relieve symptoms. If you have an infection, consult a doctor without delay if symptoms (such as fever and pain) persist or worsen (see section 2). If you take more tablets than you should or if children have taken the medicine by accident always contact a doctor or nearest hospital to get an opinion of the risk and advice on action to be taken. Bring any remaining tablets with you to show your doctor. The symptoms can include nausea, stomach pain, vomiting (may be blood streaked), headache, ringing in the ears, confusion and shaky eye movement. At high doses, drowsiness, chest pain, palpitations, loss of consciousness, convulsions (mainly in children), weakness and dizziness, blood in urine, cold body feeling, and breathing problems have been reported.
4. Possible side effects
Like all medicines, your medicine can cause side effects, although not everybody gets them.
The following effects are very rare (less than 1 in 10,000 people) but if you experience any of the effects then STOP taking this medicine immediately and contact your doctor or pharmacist.
- Peptic ulceration or perforation: Symptoms could include severe abdominal pain, vomiting blood (or liquid with what looks like coffee grounds), blood in the faeces (stools/motions) or passing black tarry stools.
- Inflammation of the brain lining. Symptoms could include stiff neck, headache, nausea, vomiting, fever or feeling disorientated. • Severe allergic reactions. Symptoms could include dizziness or fainting, faster heart rate, swelling of the face, tongue and throat. • Worsening of asthma and wheezing or difficulty breathing.
Other Possible Side Effects
Less than 1 in 100 people may experience the following uncommon side effects:
- Allergic Reactions: Hives, skin rashes and itching.
- Stomach: Abdominal pain, indigestion, heartburn and nausea.
- Nervous system: Headache.
Less than 1 in 1000 people may experience the following rare side effects:
- Diarrhoea, wind, constipation and vomiting.
Less than 1 in 10,000 people may experience the following very rare side effects:
- Reduction in blood cells, which can make the skin pale or yellow, cause fever, sore throat, mild mouth ulcers, flu-like symptoms, exhaustion or weakness, easy bruising, or bleeding from the skin or nose.
- High blood pressure, heart failure or chest pain.
- Nervousness, visual impairment, ringing in the ears and vertigo.
- Liver problems. Symptoms could include yellowing of the skin or the whites of the eyes.
- Kidney problems. Symptoms could include swelling of the ankles.
Severe skin reactions. Symptoms could include blistering.
A severe skin reaction known as DRESS syndrome can occur. Symptoms of DRESS include: skin rash, fever, swelling of lymph nodes and an increase of eosinophils (a type of white blood cells).
- Chest pain, which can be a sign of a potentially serious allergic reaction called Kounis syndrome.
Medicines such as Anadin Joint Pain may be associated with a small increased risk of heart attack ("myocardial infarction") or stroke. Frequency “Not known”
- Reddish non-elevated, target-like or circular patches on the trunk, often with central blisters, skin peeling, ulcers of mouth, throat, nose, genitals and eyes. These serious skin rashes can be preceded by fever and flu-like symptoms [exfoliative dermatitis, erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis].
- Widespread rash, high body temperature and enlarged lymph nodes (DRESS syndrome).
- A red, scaly widespread rash with bumps under the skin and blisters mainly localized on the skin folds, trunk, and upper extremities accompanied by fever at the initiation of treatment (acute generalised exanthematous pustulosis). Stop using Anadin Joint Pain if you develop these symptoms and seek medical attention immediately. See also section 2.
- When taken at higher than recommended doses or for a prolonged period of time, this medicine can cause damage to your kidneys and affect them removing acids properly from your blood into the urine (renal tubular acidosis). It can also cause very low levels of potassium in your blood (see section 2). This is a very serious condition and will require immediate treatment. Signs and symptoms include muscle weakness and light-headedness.
- Skin becomes sensitive to light.
Reporting of side effects
If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Yellow Card Scheme at www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store.
By reporting side effects you can help provide more information on the safety of this medicine.
5. How to store your medicine
- Do not use this medicine after the expiry date shown on the end of the carton. Do not store above 25°C. • Keep out of the sight and reach of children.
6. Further information
What does this medicine contain?
The active substance is ibuprofen. Your medicine contains 200mg of ibuprofen in each coated tablet.
Each tablet also contains: maize starch, pregelatinised starch, silica colloidal anhydrous, croscarmellose sodium, stearic acid, sodium lauryl sulfate. The coating contains the following ingredients: shellac, povidone, acetylated monoglycerides, sucrose, titanium dioxide, purified water, iron oxide red, sodium benzoate, propylparahydroxybenzoate (E216), methylparahydroxybenzoate (E218), microcrystalline cellulose, carnauba wax. Your medicine are coated tablets, available in packs containing 16 tablets.
Who makes this medicine?
Your medicine is manufactured by: Haleon Italy Manufacturing Italy S.r.l.,
Via Nettunense, 90 - 04011 Aprilia (LT), Italy.
The Marketing Authorisation Holder is: Haleon UK Trading Limited,
The Heights, Weybridge, Surrey, KT13 0NY, U.K.
This leaflet was last revised in: May 2025.