Patient leaflet - Conotrane cream
1. What Conotrane is and what it is used for
Conotrane Cream contains the active substances benzalkonium chloride and dimeticone. Conotrane Cream is used to protect the skin from moisture, irritants, chafing and contamination with bacteria or yeasts. It is used in the prevention and treatment of nappy rash and can also be used in the prevention of pressure sores and for other skin irritations caused by rubbing or moisture.
How Conotrane Cream works
Conotrane Cream acts as a barrier cream. The active substance, dimeticone, is water repellent and the other active substance, benzalkonium chloride, has antiseptic properties.
2. What you need to know before you use Conotrane
Do not use Conotrane Cream:
if you are allergic to benzalkonium chloride or dimeticone or any of the other ingredients of this medicine (listed in section 6).
Warnings and precautions
Talk to your doctor, pharmacist or nurse before using Conotrane Cream.
Conotrane contains paraffin. Do not smoke or go near naked flames - risk of severe burns. Fabric (clothing, bedding, dressings etc) that has been in contact with this product burns more easily and is a serious fire hazard. Washing clothing and bedding may reduce product build- up but not totally remove it.
Other medicines and Conotrane Cream
Tell your doctor or pharmacist if you are using, have recently used or might use any other medicines.
Pregnancy and breast-feeding
If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before using this medicine.
You should not apply this medicine to the breasts if you are breast‑feeding because the baby may take it in with your milk.
Conotrane Cream contains cetostearyl alcohol
Conotrane Cream contains cetostearyl alcohol which may cause local skin reactions (e.g. contact dermatitis).
This medicine contains benzalkonium chloride 0.1% w/w which is equivalent to 1.0 mg/g. Benzalkonium chloride may irritate the skin.
3. How to use Conotrane
This medicine is for cutaneous use. Always use this medicine exactly as described in this leaflet or as your doctor, pharmacist or nurse has told you. Check with your doctor, pharmacist or nurse if you are not sure. The cream is for external use only and should be applied to the affected area(s) several times a day as needed. For nappy rash, the cream should be applied at every nappy change.
If the symptoms persist for more than 14 days without improvement consult your doctor.
4. Possible side effects
Like all medicines, this medicine can cause side effects, although not everybody gets them. On rare occasions, the active ingredient benzalkonium chloride has caused irritation of the skin at the site of application. If this occurs, you should stop using Conotrane Cream immediately and consult your doctor if the irritation persists.
Reporting of side effects
If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Yellow Card Scheme at: www.mhra.gov.uk/yellowcard.
By reporting side effects you can help provide more information on the safety of this medicine.
5. How to store Conotrane
Keep this medicine out of the sight and reach of children.
Do not use this medicine after the expiry date which is stated on the tube and carton, after EXP. The expiry date refers to the last day of that month.
Do not store above 25°C (which is normal room temperature).
Do not throw away any medicines via wastewater or household waste. Ask your pharmacist how to throw away medicines no longer required. These measures will help protect the environment.
6. Contents of the pack and other information
What Conotrane Cream contains
- The active substances are benzalkonium chloride 0.1% w/w and dimeticone 22% w/w.
The other ingredients are cetostearyl alcohol, macrogol cetostearyl ether, white soft paraffin, light liquid paraffin, macrogol, potassium dihydrogen orthophosphate, geranium (fragrance) and water.
What Conotrane Cream looks like and contents of the pack
Conotrane Cream is a smooth white cream and is available in a tube containing 100 g or a tube containing 500 g.
Not all package sizes may be marketed.
Marketing Authorisation Holder and Manufacturer
Marketing Authorisation Holder:
Evolan Pharma AB, Box 120, 182 12 Danderyd, Sweden.
info@evolan.se
Manufacturer:
Laleham Health and Beauty Limited,
Fairfield, Bradshaw Lane, Kirkham, Preston, Lancashire PR4 3JA, UK
or
GMP Manufacturing Ltd,
Marfleet House, Valletta St, Hull HU9 5NP, UK
This leaflet was last revised in April 2026