THR Certification Mark

Taking the product with other medicines (continued)

Some medicines for high blood pressure: amlodipine, nifedipine, felodipine, verapamil.

A medicine for regulating mood: Lithium.

A thyroid hormone:- Thyroxine.

St John’s Wort may also affect the following medicines, therefore do not take this product with these medicines unless a doctor has said it is safe to do so:

• fentanyl, propofol, sevofl urane and midazolam (anaesthetics/pre-operative medicines).
• tramadol (an analgesic).
• erythromycin, clarithromycin and telithromycin (antibiotics).
• itraconazole and voriconazole (antifungals).
• artemether and lumefantrine (antimalarials).
• rasagiline (anti-Parkinson’s me­dicine).
• aripiprazole (an antipsychotic medicine).
• buspirone (an anxiolytic).
• aprepitant (used to treat post-operative vomiting).
• butobarbital and phenobarbital (barbiturates).
• methyl phenidate (a central nervous system or CNS stimulant).
• exemestane (a hormone antagonist).
• eplerenone (a diuretic).
• lansoprazole and omeprazole (proton pump inhibitors).
• theophylline (a bronchodilator).
• gliclazide (an antidiabetic medicine).

3. how to take this product

Adults and the elderly: Take 1 tablet daily. Swallow the tablet whole with some water or other liquid. Do not chew.

Do not exceed the stated dose.

If you take too much of this product (overdose)

If you take more than the recommended dose , speak to a doctor, pharmacist or qualified healthcare practitioner and take this leaflet with you.

If you forget to take this product

Continue to take your usual dose at the usual time. It does not matter if you have missed a dose.

If symptoms worsen, or do not improve after 6 weeks consult your doctor or qualified healthcare practitioner or pharmacist.

If you have any questions, or are unsure about anything, please ask your doctor, pharmacist or qualified healthcare practitioner.

4. possible side effects

Like all medicines, this product can cause side effects.

The following side effects have been reported:

• Gastrointestinal disorders such as indigestion, loss of appetite, nausea, diarrhoea and constipation.
• Fatigue and restlessness.
• Allergic reactions such as a rash, hives or itching of the skin. If you experience allergic reaction, stop taking the product and consult your doctor.

Also sunburn-like reactions on skin exposed to strong sunlight or strong ultra-violet (UV) irradiation e.g. solarium have been reported, particularly in fair skinned individuals. Other side effects that have been reported include headaches, nerve pain or tingling, anxiety, dizziness and mania.

If any of the side effects become serious or if you notice a side effect not listed in this leaflet, please tell your doctor, pharmacist or qualified healthcare practitioner.

If you get any side effects, talk to your doctor, pharmacist or qualified healthcare practitioner. This includes any possible side effects not listed in the package leaflet. You can also report side effects directly via the Yellow Card Scheme at or search for MHRA Yellow Card in the Google Play or Apple App Store.

By reporting side effects you can help provide more information on the safety of this medicine

5. how to store st john’s wort tablets

THR Certification Mark

Taking the product with other medicines (continued)

Some medicines for high blood pressure: amlodipine, nifedipine, felodipine, verapamil.

A medicine for regulating mood: Lithium.

A thyroid hormone:- Thyroxine.

St John’s Wort may also affect the following medicines, therefore do not take this product with these medicines unless a doctor has said it is safe to do so:

• fentanyl, propofol, sevofl urane and midazolam (anaesthetics/pre-operative medicines).
• tramadol (an analgesic).
• erythromycin, clarithromycin and telithromycin (antibiotics).
• itraconazole and voriconazole (antifungals).
• artemether and lumefantrine (antimalarials).
• rasagiline (anti-Parkinson’s me­dicine).
• aripiprazole (an antipsychotic medicine).
• buspirone (an anxiolytic).
• aprepitant (used to treat post-operative vomiting).
• butobarbital and phenobarbital (barbiturates).
• methyl phenidate (a central nervous system or CNS stimulant).
• exemestane (a hormone antagonist).
• eplerenone (a diuretic).
• lansoprazole and omeprazole (proton pump inhibitors).
• theophylline (a bronchodilator).
• gliclazide (an antidiabetic medicine).

3. how to take this product

Adults and the elderly: Take 1 tablet daily. Swallow the tablet whole with some water or other liquid. Do not chew.

Do not exceed the stated dose.

If you take too much of this product (overdose)

If you take more than the recommended dose , speak to a doctor, pharmacist or qualified healthcare practitioner and take this leaflet with you.

If you forget to take this product

Continue to take your usual dose at the usual time. It does not matter if you have missed a dose.

If symptoms worsen, or do not improve after 6 weeks consult your doctor or qualified healthcare practitioner or pharmacist.

If you have any questions, or are unsure about anything, please ask your doctor, pharmacist or qualified healthcare practitioner.

4. possible side effects

Like all medicines, this product can cause side effects.

The following side effects have been reported:

• Gastrointestinal disorders such as indigestion, loss of appetite, nausea, diarrhoea and constipation.
• Fatigue and restlessness.
• Allergic reactions such as a rash, hives or itching of the skin. If you experience allergic reaction, stop taking the product and consult your doctor.

Also sunburn-like reactions on skin exposed to strong sunlight or strong ultra-violet (UV) irradiation e.g. solarium have been reported, particularly in fair skinned individuals. Other side effects that have been reported include headaches, nerve pain or tingling, anxiety, dizziness and mania.

If any of the side effects become serious or if you notice a side effect not listed in this leaflet, please tell your doctor, pharmacist or qualified healthcare practitioner.

If you get any side effects, talk to your doctor, pharmacist or qualified healthcare practitioner. This includes any possible side effects not listed in the package leaflet. You can also report side effects directly via the Yellow Card Scheme at or search for MHRA Yellow Card in the Google Play or Apple App Store.

By reporting side effects you can help provide more information on the safety of this medicine

5. how to store st john’s wort tablets

Keep out of the reach and sight of children.

Do not store above 25 °C.

Store in original packaging.

Do not use your tablets after the expiry date which is stated on the box and the blister pack. The expiry date refers to the last day of that month.

Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.

• 6. Further Information