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TIXYLIX INFANT COUGH SYRUP, TIXYLIX CHILDRENS COUGH SYRUP - summary of medicine characteristics

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Summary of medicine characteristics - TIXYLIX INFANT COUGH SYRUP, TIXYLIX CHILDRENS COUGH SYRUP

1. NAME OF THE MEDICINAL PRODUCT

Tixylix Infant Cough Syrup

Tixylix Children’s Cough Syrup

2 QUALITATIVE AND QUANTITATIVE COMPOSITION

Active ingredient:

Glycerol 0.75ml per 5 ml

Excipient(s) with known effect:

Liquid maltitol (Lycasin) 2.16g/5ml dose.

Sodium benzoate (E 211) 10mg per 5ml dose.

Propylene glycol (E 1520) 34mg per 5ml dose.

Vanilla flavour (contains propylene glycol E1520)

Blackcurrant flavour (contains propylene glycol E1520)

For the full list of excipients, see section 6.1

3 PHARMACEUTICAL FORM

Syrup

A clear viscous liquid

CLINICAL PARTICULARS

4.1

Therapeutic indications

For the relief of dry tickly coughs

4.2

Posology and method of administration

For oral administration.

Children 3 months to under 1 year:

One 5 ml spoonful three to four times a da

Children 1 to 5 years:

Two 5 ml spoonfuls three to four times a day

Allow 3 to 4 hours between doses.

Children under 3 months:

Not recommended

4.3 Contraindications

Hypersensitivity to any of the ingredients.

4.4 Special warnings and precautions for use

Not recommended for children under 3 months.

If symptoms persist for more than 3 days consult your doctor.

Important information about some of the ingredients:

This medicine contains:

Sodium benzoate (E211), 10mg per 5ml dose.

Maltitol may have a mild laxative effect. Calorific value 2.3Kcal/g. If you have been told by your doctor that your child is intolerant to some sugars, contact your doctor before taking this medicinal product.

Patients with rare hereditary problems of fructose intolerance should not take this medicine.

This medicine contains 34mg propylene glycol (E1520) in each 5ml dose.

Less than 1mmol sodium (23mg) per 5ml dose, that is to say essentially “sodium-free”.

4.5 Interaction with other medicinal products and other forms of interaction

No known drug interactions exist.

4.6 Fertility, Pregnancy and lactation

No data are available for glycerol on exposed pregnancies or use during lactation.

Caution should be exercised when prescribing during pregnancy.

4.7 Effects on ability to drive and use machines

On the basis of the known pharmacodynamic and adverse event profile for glycerol, this medicine has no major influence on the ability to drive and use machinery.

4.8 Undesirable effects

No adverse effects known.

Reporting of suspected adverse reactions

Reporting suspected adverse reactions after authorisation of the medicinal product is important. It allows continued monitoring of the benefit/risk balance of the medicinal product. Healthcare professionals are asked to report any suspected adverse reactions via the Yellow Card Scheme at: www.mhra.gov.uk/yellowcard.

4.9 Overdose

4.9 Overdose

Overdosage with this product may possibly cause diarrhoea. Treatment should be symptomatic.

PHARMACOLOGICAL PROPERTIESPHARMACOLOGICAL PROPERTIES

5.1

Pharmacodynamic properties

Glycerol has demulcent properties and may possibly block sensory cough receptors in the respiratory tract.

5.2 Pharmacokinetic properties

None stated.

5.3 Preclinical safety data

None stated.

6.1 List of excipients

Liquid maltitol (Lycasin)

Hydroxyethylce­llulose

Sodium Benzoate (E211)

Citric Acid Monohydrate

Sodium Citrate

Vanilla flavour (contains propylene glycol E1520)

Blackcurrant flavour (contains propylene glycol E1520)

Purified Water

6.2 Incompatibilities

None stated.

6.3 Shelf life

36 months

6.4 Special precautions for storage

Keep the container tightly closed Do not store above 25°C

6.5 Nature and contents of container

Container: Amber-coloured glass bottle

Closure: Child resistant cap

Measuring spoon provided.

Pack size: 100ml, 150ml

Container: Amber-coloured polyethylene teraphthalate bot­tle

Closure: Child resistant cap

Measuring spoon provided.

Pack size: 150ml

6.6 Special precautions for disposal

6.6 Special precautions for disposal

Not applicable.