Patient leaflet - Tillomed Diarrhoea Relief 2 mg capsules
1. What Tillomed Diarrhoea Relief is and what it is used for
The active ingredient in Tillomed Diarrhoea Relief is Loperamide hydrochloride which belongs to a group of medicines called ’antidiarrhoeals’ which are used to treat diarrhoea. It helps reduce diarrhoea by slowing down an overactive bowel. This allows water and salts that are usually lost in diarrhoea to be absorbed by the body. Tillomed Diarrhoea Relief is used to treat:
- short-lived (acute) attacks of diarrhoea
- sudden short lived (acute) attacks of diarrhoea in adults and children aged 12 years and over
- episodes of diarrhoea in adults and young people aged 18 and over who have been diagnosed with Irritable Bowel Syndrome (IBS) For IBS diarrhoea, you can use this medicine for up to 2 weeks for repeated attacks, but if any one attack lasts continuously for longer than 48 hours, talk to your doctor.
2. What you need to know before you take Tillomed Diarrhoea Relief
Do not take Tillomed Diarrhoea Relief if:
- you are allergic to Loperamide or any of the other ingredients of this medicine (listed in section 6)
- it is for a child aged under 12 (or under 18 for an IBS patient)
- you need to keep the bowel movements normal to avoid complications such as blockage of the bowel and abnormal or rapid widening of the colon
- you have constipation, blockage of the bowel or a bloated tummy
- you have a flare-up of ulcerative colitis (a form of inflammatory bowel disease) which can cause abdominal pain, bloody diarrhoea, fever and weight loss
- you have severe diarrhoea after taking antibiotics (symptoms may include watery or bloody diarrhoea)
- you have a bacterial infection of the small intestine and colon (caused by bacteria such as salmonella, shigella and campylobacter)
- you have inflammation of the colon after taking antibiotics (symptoms may include watery or bloody diarrhoea)
- you have acute (short-lived) dysentery, the symptoms of which may include blood in your stools and a high temperature
Warnings and precautions
Do not take this product for anything other than its intended use (see section 1) and never take more than the recommended amount (see section 3). Serious heart problems (symptoms of which include fast or irregular heartbeat) have been reported in patients who have taken too much Loperamide, the active ingredient in Tillomed Diarrhoea Relief.
Stop taking Loperamide and talk to your doctor if there is no improvement in your symptoms within 48 hours.
Talk to your doctor before taking Tillomed Diarrhoea Relief if:
- you have or think you may have lost body fluids and salts through diarrhoea. Particularly important for children and frail or elderly patients with severe diarrhoea (see ‘Replacing fluids and salts’, section 3)
you have liver disease. You should consult
your doctor or pharmacist before taking Loperamide as it may cause side effects
- you are taking Loperamide to treat diarrhoea caused by Irritable Bowel Syndrome (IBS). See “Special warnings for IBS patients” section
- you have a bloated tummy and you have AIDS. You should stop taking the capsules immediately and contact your doctor Consult a doctor before use if you have a history of drug abuse; loperamide is an opioid and addiction is observed with opioids as a class.
Special warnings for IBS patients
Only take this medicine to treat episodes of diarrhoea associated with Irritable Bowel Syndrome if your doctor has previously diagnosed IBS.
If any of the following apply, do not use this medicine without first consulting your doctor, even if you know you have IBS:
- If you are aged 40 or over and it is some time since your last IBS attack
- If you are aged 40 or over and your IBS symptoms are different this time
- If you have recently passed blood from the bowel
- If you suffer from severe constipation
- If you are feeling sick or vomiting
- If you have lost your appetite or lost weight
- If you have difficulty or pain passing urine
- If you have a fever
- If you have recently travelled abroad Consult your doctor if you develop new symptoms, or if your symptoms worsen, or your symptoms have not improved over two weeks.
Other medicines and Tillomed Diarrhoea Relief
Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines, including those obtained without a prescription. This includes herbal medicines. Tillomed Diarrhoea Relief should not be taken with the following:
- Other antidiarrhoea preparations, except for oral rehydration therapy (see “Replacing fluids and salts” in section 3)
Tillomed Diarrhoea Relief may cause serious side effects if taken with the following:
- Quinidine, for abnormal and increased heart rhythm
- Ritonavir, for HIV infection and AIDS
- Itraconazole and Ketoconazole, for fungal infections
- Gemfibrozil, used to lower levels of cholesterol and other lipids (fats) in the blood Tillomed Diarrhoea Relief increases the blood levels of the following:
- Oral desmopressin, for reducing urine production (antidiuretic)
Pregnancy and breast-feeding
If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor for advice before taking this medicine.
Pregnancy
If you are pregnant or planning to become pregnant, you are advised not to take Tillomed Diarrhoea Relief. It is not known if it is safe to take, especially during the first 3 months of pregnancy.
Breast-feeding
If you are breast-feeding, you should not take Tillomed Diarrhoea Relief , as small amounts of this medicine get into your breast milk.
Driving and using machines
This medicine may make you feel tired, dizzy or drowsy. You may feel less alert, feel faint or pass out. If affected, you are advised not to drive or operate machinery.
Tillomed Diarrhoea Relief contains Lactose
If you have been told by your doctor that you have intolerance to some sugars, contact your doctor before taking this medicine.
Tillomed Diarrhoea Relief contains colouring agent Sunset Yellow FCF (E110)
It may cause allergic reaction.
3. How to take Tillomed Diarrhoea Relief
Always take this medicine exactly as described in this leaflet or as your doctor has told you. Check with your doctor or pharmacist if you are not sure.
- The capsule is for oral use only
- Swallow the capsules whole with some liquid
Short-term diarrhoea
Adults and children over 12 years:
- 2 capsules (4 mg) initially, followed by 1 capsule (2 mg) after each loose stool (bowel movement)
PACKAGE LEAFLET: INFORMATION FOR THE PATIENT
Tillomed Diarrhoea Relief 2 mg Capsules
Loperamide hydrochloride
Loperamide 2 mg Capsules
Package leaflet (GSL)
110 x 28 mm
TBA
TW163719 (design)
UK
All
NA
TBA
9 points (Reg text)
NA
25/11/2024 29/11/2024 08/04/2025 09/04/2025
Black C
000
- The usual dose is 3-4 capsules (6 mg – 8 mg) a day
- The total daily dose should not exceed 6 capsules (12 mg)
Diarrhoea associated with Irritable Bowel Syndrome
Adults aged 18 years and over:
- 2 capsules (4 mg) initially, followed by 1 capsule (2 mg) after each loose stool (bowel movement), or as previously advised by your doctor
- The maximum daily dose should not exceed 6 capsules (12 mg)
- For IBS diarrhoea, you can use this medicine for up to 2 weeks for repeated attacks, but do not use if any one attack lasts continuously for longer than 48 hours and talk to your doctor.
Patients with liver problems
See ‘Warnings and precautions’ (section 2).
Use in children under 12 years:
This medicine should not be given to children under 12 years of age.
If you have diarrhoea and your symptoms do not improve within 48 hours, you should stop taking Tillomed Diarrhoea Relief and contact your doctor.
Replacing fluids and salts
When you have diarrhoea, your body loses large amounts of fluid and salts. In addition to your medicine, you should take more liquids than normal. Drink plenty of clear fluids containing salt and sugar (special oral rehydration powders are available from pharmacists). This is especially important for children, and frail or elderly people.
If you take more Tillomed Diarrhoea Relief than you should
If you have taken too many capsules, immediately contact a doctor or hospital for advice. Remember to take this leaflet or any remaining capsules with you.
Symptoms (of an overdose) may include: increased heart rate, irregular heartbeat, changes to your heartbeat (these symptoms can have potentially serious, life-threatening consequences), muscle stiffness, uncoordinated movements, drowsiness, difficulty urinating, or weak breathing.
Children react more strongly to large amounts of Tillomed Diarrhoea Relief than adults. If a child takes too much or shows any of the above symptoms, call a doctor immediately.
If you forget to take Tillomed Diarrhoea Relief
Take it as soon as you remember, unless it is nearly time for your next dose. If you miss a dose, do not take a double dose to make up for a forgotten dose.
If you have any further questions on the use of this medicine, ask your doctor or pharmacist.
4. Possible side effects
Like all medicines, Tillomed Diarrhoea Relief can cause side effects, although not everybody gets them.
Seek medical advice immediately if you develop the following (rare) symptoms:
- Bloated tummy which may be due to enlargement of the large intestine, which may cause constipation, bloating and tenderness of the stomach or fever (megacolon or toxic megacolon)
- Allergic reaction: swelling of the face, throat or tongue, difficulty breathing (anaphylaxis) and dizziness
- Severe blistering of the skin, mouth, eyes and genitals (Steven-Johnson’s Syndrome or toxic epidermal necrolysis)
- Fever, general ill feeling, itching, joint aches, multiple skin lesions (erythema multiforme)
- Swelling of the deeper layers of the skin caused by a build-up of fluid (angioedema)
- Loss of consciousness or reduced level of consciousness (passing out, feeling faint or less alert)
- Difficulty co-ordinating movement
- Difficulty in urinating (passing water)
- Severe constipation
- Blockage of the bowel
Common side effects
(may affect up to 1 in 10 people)
- Headache
Constipation
- Feeling sick (nausea)
- Stomach wind (flatulence)
Uncommon side effects
(may affect up to 1 in 100 people)
- Dizziness
- Drowsiness
- Stomach pain or discomfort
- Dry mouth
- Being sick (vomiting)
- Indigestion
- Rash
Rare side effects
(may affect up to 1 in 1,000 people)
- Abnormal increase in muscle tension
- Pupils of the eyes become smaller
- Bloated tummy
- Skin rashes with the formation of wheals
- Severe itching
- Tiredness (fatigue)
Not known (frequency cannot be estimated from the available data)
- Upper abdominal pain, abdominal pain that radiates to back, tenderness when touching the abdomen, fever, rapid pulse, nausea, vomiting, which may be symptoms of inflammation of the pancreas (acute pancreatitis)
If you get any of these, stop using the medicine and get medical help at once.
Reporting of side effects
If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Yellow Card Scheme at www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store. By reporting side effects you can help provide more information on the safety of this medicine.
5. How to store Tillomed Diarrhoea Relief
- Keep this medicine out of the sight and reach of children.
- Do not store above 25˚C. Store in the original package in order to protect from light.
- Do not use this medicine after the expiry date, which is stated on the carton/blister after “EXP”. The expiry date refers to the last day of that month.
- Do not throw away any medicines via wastewater or household waste. Ask your pharmacist how to throw away medicines you no longer use. These measures will help to protect the environment.
6. Contents of the pack and other information
What Tillomed Diarrhoea Relief contains:
Each capsule contains 2 mg of Loperamide hydrochloride.
The other ingredients are:
Lactose, maize starch, talc, magnesium stearate, gelatin, colouring agents sunset yellow FCF (E110), erythrosine (E127), patent blue (E131), indigotine (E132) and titanium dioxide (E171) (see “Tillomed Diarrhoea Relief contains Lactose and colouring agent Sunset Yellow FCF (E110)” in section 2).
What Tillomed Diarrhoea Relief looks like and the contents of the pack:
Tillomed Diarrhoea Relief are grey-dark green coloured, hard, gelatin size 3 capsules, filled with homogenous white to off white powder.
Tillomed Diarrhoea Relief is available in:
Tillomed Diarrhoea Relief is available in a pack of 6 capsules.
Not all pack sizes may be marketed.
Marketing Authorisation Holder & Manufacturer
Tillomed Laboratories Limited
220 Butterfield, Great Marlings
Luton, LU2 8DL, United Kingdom
Legal category: General Sale List (GSL)
Medicine
Product Licence Number: PL 11311/0515
This leaflet was last revised in April 2025
51052xxxxGB0x
Till-Ver.6.1
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To get this information in large print or another format, please email medical.information@tillomed.com or call 0800 970 6115.