Patient leaflet - Sumatriptan 10 mg nasal spray, solution in single dose Container
1. What Sumatriptan 10 mg nasal spray is and what it is used for
Each Sumatriptan 10 mg nasal spray contains a single dose of sumatriptan, which belongs to a group of medicines called triptans (also known as 5-HT1 receptor agonists).
Sumatriptan 10 mg nasal spray is used to treat migraine headache.
Migraine symptoms may be caused by the temporary widening of blood vessels in the head. Sumatriptan nasal spray is believed to reduce the widening of these blood vessels. This in turn helps to take away the headache and relieve other symptoms of a migraine attack, such as feeling or being sick (nausea or vomiting) and sensitivity to light and sound.
2. What you need to know before you use Sumatriptan 10 mg nasal spray
Do not use Sumatriptan 10 mg nasal spray
- If you’re allergic to sumatriptan, or any of the other ingredients of this medicine (listed in section 6).
If you have a heart problem such as narrowing of the arteries (Ischaemic heart disease) or chest pain
(angina), or have already had a heart attack.
If you have circulation problems in your legs that cause cramp-like pains when you walk (peripheral
vascular disease).
- If you have had a stroke or a mini-stroke (also called a transient ischaemic attack or TIA).
If you have high blood pressure. You may be able to use Sumatriptan 10 mg nasal spray if your high blood
pressure is mild and is being treated.
- If you have serious liver disease.
With other migraine medicines, including those which contain ergotamine, or similar medicines such as
methysergide or any triptan/5-HT1 receptor agonist (medicines which are also used for treating migraine).
- With anti-depressants called MAOIs (monoamine oxidase inhibitors), or if you have taken these
medicines in the last 2 weeks. If any of these apply to you: Tell your doctor, and don’t use Sumatriptan |
10 mg nasal spray.
Warnings and precautions Talk to your doctor or pharmacist before using |
Sumatriptan 10 mg nasal spray.
| If you have any extra risk factors If you are a heavy smoker, or are using nicot |
ine replacement therapy, and especially
| If you are a man aged over 40, or If you are a woman who has been through t |
he menopause.
| In very rare cases, people have developed serio |
us heart conditions after using Sumatriptan 10 mg nasal spray, even
| though they had no signs of heart disease befo |
re. If any of the points above applies to you it could mean you have
| a greater risk of developing heart disease - so: Tell your doctor so that your heart funct |
ion can be checked before Sumatriptan 10 mg nasal spray is
prescribed for you. If you have a history of fits (seizures) Or if you have other conditions which might m |
ake it more likely that you’ll have a fit – for example, a head injury
or alcoholism: Tell your doctor so that you can be supervis |
ed more closely.
| If you have liver or kidney disease Tell your doctor so that you can be supervis |
ed more closely.
If you are allergic to antibiotics called sulphonamides
If so, you may also be allergic to Sumatriptan. If you know you are allergic to an antibiotic but you are not sure whether it is a sulphonamide:
Tell your doctor or pharmacist before using Sumatriptan 10 mg nasal spray.
If you are taking anti-depressants called SSRIs (Selective Serotonin Reuptake Inhibitors) or SNRIs (Serotonin Noradrenaline Reuptake Inhibitors)
Tell your doctor or pharmacist before using Sumatriptan 10 mg nasal spray. Also see Other medicines and Sumatriptan 10 mg nasal spray, below.
If you use Sumatriptan 10 mg nasal spray frequently.
Using Sumatriptan too often may make your headaches worse.
Tell your doctor if this applies to you. He or she may recommend you stop using Sumatriptan 10 mg nasal spray.
If you feel pain or tightness in your chest after you use Sumatriptan 10 mg nasal spray
These effects may be intense but they usually pass quickly. If they don’t pass quickly, or they become severe: Get medical help immediately. Section 4 of this leaflet has more information about these possible side effects.
Other medicines and Sumatriptan 10 mg nasal spray
Tell your doctor or pharmacist if you’re taking, have recently taken or might take any other medicines. This includes any herbal products or medicines you’ve bought without a prescription.
Some medicines must not be taken with Sumatriptan 10 mg nasal spray and others may cause adverse effects if they’re taken with Sumatriptan 10 mg nasal spray. You must tell your doctor if you are taking: • ergotamine also used to treat migraine, or similar medicines such as methysergide (see section 2 Don’t use
Sumatriptan 10 mg nasal spray). Don’t use Sumatriptan 10 mg nasal spray at the same time as these medicines. Stop taking these medicines at least 24 hours before using Sumatriptan 10 mg nasal spray. Don’t take any medicines which contain ergotamine or compounds similar to ergotamine again for at least 6 hours after using Sumatriptan 10 mg nasal spray.
other triptans/5-HT1 receptor agonists (such as naratriptan, rizatriptan, zolmitriptan), also used to treat
migraine, (see section 2 Don’t use Sumatriptan 10 mg nasal spray). Don’t use Sumatriptan 10 mg nasal spray at the same time as these medicines. Stop taking these medicines at least 24 hours before using Sumatriptan 10 mg nasal spray. Don’t take another triptan/5-HT1 receptor agonist again for at least 24 hours after using Sumatriptan 10 mg nasal spray.
SSRIs (Selective Serotonin Reuptake Inhibitors) or SNRIs (Serotonin Noradrenaline Reuptake Inhibitors)
used to treat depression. Using Sumatriptan 10 mg nasal spray with these medicines can cause serotonin syndrome (a collection of symptoms which can include restlessness, confusion, sweating, hallucinations, increased reflexes, muscle spasms, shivering, increased heart beat and shaking). Tell your doctor immediately if you are affected in this way.
MAOIs (monoamine oxidase inhibitors) used to treat depression. Don’t use Sumatriptan 10 mg nasal spray
if you have taken these in the last 2 weeks.
St John’s Wort (Hypericum perforatum). Taking herbal remedies that contain St John’s Wort while you are
using Sumatriptan may make side effects more likely.
Pregnancy and breast-feeding
If you are pregnant, think you may be pregnant or are planning to have a baby, ask your doctor for
advice before taking this medicine. There is only limited information about the safety of Sumatriptan 10 mg nasal spray for pregnant women, though up till now there is no evidence of any increased risk of birth defects. Your doctor will discuss with you whether or not you should use Sumatriptan 10 mg nasal spray while you are pregnant.
Don’t breast-feed your baby for 12 hours after using Sumatriptan 10 mg nasal spray. If you express any
breast milk during this time, discard the milk and don’t give it to your baby.
Driving and using machines
Either the symptoms of migraine or your medicine may make you drowsy. If you are affected, don’t drive or operate machinery.
Sumatriptan 10 mg nasal spray contains sodium
This medicine contains less than 1 mmol sodium (23 mg) per dose, that is to say essentially ‘sodium-free’.
3. How to use Sumatriptan 10 mg nasal spray
Only use Sumatriptan 10 mg nasal spray after your migraine headache begins.
Don’t use Sumatriptan 10 mg nasal spray to try to prevent an attack.
Always use this medicine exactly as your doctor has told you. Check with your doctor or pharmacist if you are not sure.
There’s a step-by-step guide to using the spray at the end of this leaflet (see section 6).
How much to use
Adults aged 18 to 65
The usual dose for adults aged 18 to 65 is one Sumatriptan 20 mg spray into just one nostril. But one Sumatriptan 10 mg spray into one nostril is enough for some people.
Don’t use more than two sprays in 24 hours.
Adolescents aged 12 to 17
- The usual dose for adolescents aged 12 to 17 is one Sumatriptan 10 mg spray into one nostril.
Children under 12
- Sumatriptan 10 mg nasal spray is not recommended for children under 12 years old.
Older people (aged over 65)
- Sumatriptan 10 mg nasal spray is not recommended for people aged over 65.
When to use Sumatriptan 10 mg nasal spray
It’s best to use Sumatriptan 10 mg nasal spray as soon as you feel a migraine coming on, although it
can be used at any time during an attack.
If your symptoms start to come back
You can use a second Sumatriptan 10 mg nasal spray after 2 hours, but don’t use more than two sprays in
24 hours.
If the first spray has no effect
Don’t use a second spray, or any other Sumatriptan 10 mg nasal spray preparation for the same attack. If
Sumatriptan 10 mg nasal spray doesn’t give you any relief:
Ask your doctor or pharmacist for advice.
If you use more Sumatriptan 10 mg nasal spray than you should
- Don’t use more than two Sumatriptan 10 mg nasal spray in 24 hours
Using too much Sumatriptan10 mg nasal spray could make you ill. If you have used more than two sprays in 24 hours:
Contact your doctor for advice.
If you have any further questions on the use of this medicine, ask your doctor or pharmacist.
4. Possible side effects
Like all medicines, this medicine can cause side effects, although not everybody gets them. Some symptoms may be caused by the migraine itself. Adverse events reported in adults have also been observed in adolescents. These include very rare reports of heart attacks.
Allergic reaction: get doctor’s help straight away
The following side effects have occurred but their exact frequency is not known.
- The signs of allergy include rash, hives (itchy rash); wheezing; swollen eyelids, face or lips; complete collapse.
If you get any of these symptoms soon after using Sumatriptan 10 mg nasal spray:
Don’t use any more. Contact a doctor straight away.
Very common side effects
(affect more than 1 in 10 people)
Unpleasant taste.
Common side effects
(affect up to 1 in 10 people)
Pain, heaviness, pressure, tightness or pain in the chest, throat or other parts of the body, or feelings of
unusual sensations, including numbness, tingling and warmth or cold. These effects may be intense but generally pass quickly.
If these effects continue or become severe (especially the chest pain):
Get medical help urgently. In a very small number of people these symptoms can be caused by a heart attack.
Other common side effects include:
- Irritation or burning sensation in the nose or throat; nose bleeds.
- Feeling sick (nausea) or being sick (vomiting), although this may be due to the migraine itself.
- Tiredness or drowsiness.
- Dizziness, feeling weak, or getting hot flushes.
- Temporary increase in blood pressure.
- Shortness of breath
- Aching muscles.
Very rare side effects
(affect up to 1 in 10,000 people)
Liver function changes. If you have a blood test to check your liver function, tell your doctor or nurse that
you are using Sumatriptan 10 mg nasal spray.
Some patients may have the following side effects but it is not known how often they occur
- Seizures/fits, tremors, muscle spasm, neck stiffness.
Visual disturbances such as flickering, reduced vision, double vision, loss of vision, and in some cases even
permanent defects (although these may be due to the migraine attack itself).
Heart problems, where your heart beat may go faster, slower or change rhythm, chest pains (angina) or heart
attack.
Pale, blue-tinged skin and/or pain in your fingers, toes, ears, nose or jaw in response to cold or stress
(Raynaud’s phenomenon).
- Feeling faint (blood pressure may go down).
- Pain in the lower left side of the stomach and bloody diarrhoea (ischaemic colitis). • Diarrhoea.
If you had a recent injury or if you have inflammation (like rheumatism or inflammation of the colon) you
may experience pain or pain worsening at the site of injury or inflammation.
- Pain in the joints.
- Feeling anxious.
- Difficulty swallowing.
- Excessive sweating.
Reporting of side effects
If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via Yellow Card Scheme at: www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store. By reporting side effects you can help provide more information on the safety of this medicine.
5. How to store Sumatriptan 10 mg nasal spray
Keep this medicine out of the sight and reach of children.
Don’t store above 30°C and don’t freeze.
Don’t use this medicine after the expiry (EXP) date shown on the carton. The expiry date refers to the last day of that month.
Don’t throw away any medicines via waste water or household waste. Ask your pharmacist how to throw away medicines you no longer use. These measures will help protect the environment.
6. Contents of the pack and other information
What Sumatriptan 10 mg nasal spray contains
The active substance is sumatriptan.
Each Sumatriptan 10 mg nasal spray contains 10 mg sumatriptan.
The other ingredients are: sulfuric acid, anhydrous dibasic sodium phosphate, dihydrogen potassium phosphate, sodium hydroxide and water for injection.
What Sumatriptan 10 mg nasal spray looks like and contents of the pack
This medicine is provided in a pre-filled nasal spray device and contains sumatriptan in 0.1 ml of a yellow-coloured solution.
Sumatriptan 10 mg nasal spray is packed in a box containing the nasal sprays individually sealed in blisters. They are available in packs of 2 pre-filled nasal spray devices, although not all pack sizes may be available in your country. Each nasal spray contains one dose of Sumatriptan 10 mg nasal spray.
Marketing Authorisation Holder
Universal Farma, S.L.
c/ Dulcinea, s/n
28805 Alcalá de Henares, Madrid
(Spain)
Manufacturer
Universal Farma, S.L.
Polígono Industrial Miralcampo
C/ Del Tejido, 2
19200 Azuqueca de Henares
Guadalajara
Spain
This leaflet was last revised in February 2026.
Detailed information on this medicine is available on the Medicines & Healthcare products Regulatory Agency website: www.mhra.gov.uk.
Step-by-step guide to using your Sumatriptan 10 mg nasal spray
Don’t open a blister until you are ready to use a spray. Each spray is sealed in a blister to keep it clean and safe. If you carry a spray without a blister, or in an open blister, it may not work properly when you need it.
Each spray contains just one dose of Sumatriptan 10 mg nasal spray
Don’t press the plunger too soon or you will lose the dose
A. The Protective Cover:
- This covers the nozzle to protect it.
- Remove it before you use the nasal spray.
B. The Nozzle:
- You put this part into your nose.
- The medicine comes out of a tiny hole in the top.
C. The Finger-grip
- You hold this part when you use the spray.
D. The Plunger:
- You press this part once you have put the nozzle comfortably into your nose. • The spray contains only one dose and works only once.
Do not press the plunger until you have put the nozzle in your nostril or you will lose the dose.
1 • Blow your nose gently before use. 1
- Remove the protective cover.
2 • Hold the nasal spray gently with 2 your fingers and thumb as shown in picture 2.
Do not press the plunger yet!
3 • Block one nostril by pressing a 3 finger on the side of your nose as shown in picture 3. (If you already have a blocked nostril as a symptom of your illness this may not be needed.)
- Put the nozzle of the nasal spray into the other unblocked nostril as far as feels comfortable.
- Tilt your head back slightly and close your mouth as shown in picture 3.
- Breathe in gently through your nose and at the same time press the plunger firmly with your thumb. The plunger may feel stiff and you may hear it click.
- Keep your head slightly tilted back. Remove the nozzle from your nose.
Breathe gently through your mouth for
5-10 seconds. You may feel liquid inside your nose. This does not mean that the dose is being lost or that the spray has failed. This is normal and will soon pass.