SECURON SR 240 MG TABLETS - patient leaflet, side effects, dosage

To correct the errors from variation 0003 to split multiple licence leaflet into separate leaflets

5. how to store securon sr

Keep out of the sight and reach of children.

Do not store above 25°C. Store in the original package. Do not take this medicine after the expiry date shown on the carton and blister label. If your doctor tells you to stop taking this medicine, take any remaining medicine back to the pharmacist for safe disposal.

Only keep this medicine if your doctor tells you to.

• Medicines should not be disposed of via waste water or household waste. Ask your pharmacist how to dispose of medicines that are no longer required. These measures will help to protect the environment.
• If your medicine becomes discoloured or show any other signs of deterioration, ask your pharmacist who will advise you what to do.

6. contents of the pack and other information

What this medicine contains:

• Securon SR tablets contain the active ingredient verapamil hydrochloride in a sustained-release (slow release) formulation.
• Each Securon SR modified-release tablet contains 240mg of verapamil hydrochloride.
• The other ingredients are: microcrystalline cellulose, sodium alginate, povidone, magnesuim stearate, purified water, hypromellose, macrogol 400, macrogol 6000, talc, titanium dioxide E171, and montan glycol wax, quinoline yellow E104 and indigotine E132.

What this medicine looks like and contents of the pack

• Securon SR tablets are oblong, pale, green tablet scored on both sides and embossed with two triangles on one side.

Manufacturer and Licence Holder

This medicine is manufactured by FAMAR A.V.E ANTHOUSSA PLANT, Anthoussa Avenue 7, Anthoussa Attiki, 15344, Greece and is procured from within the EU and repackaged by the Product Licence Holder: Lexon (UK) Limited, Unit 18, Oxleasow Road, East Moons Moat, Redditch, Worcestershire, B98 0RE.

If you have any questions or are not sure about anything, ask your doctor or pharmacist. They will have additional information about this medicine and will be able to advise you.

I POM PL 15184/1873 Securon SR 240mg Tablets

Securon SR is registered trademarks of Mylan Healthcare GmbH.

Leaflet revision date: 20/07/21

Blind or partially sighted? Is this leaflet hard to see or read? Phone Lexon (UK) Limited,

Tel: 01527 505414 to obtain the leaflet in a format suitable for you

IMPORTANT INFORMATION

Read all of this leaflet carefully before you start taking this medicine

• keep this leaflet as you may need to read it again
• this leaflet provides a summary of the information currently available about Securon SR
• for further information or advice ask your doctor or pharmacist
• this medicine is for you only and should never be given to anyone else, even if they appear to have the same symptoms as you
• tell your doctor or pharmacist if you experience any side effects

Your medicine is called Securon SR 240mg Tablets and will be referred to as Securon SR throughout the rest of this leaflet.

Please note this leaflet also contains information about other strengths of this medicine Half

Securon SR 120mg Tablets

Leaflet contents:

• 1. What Securon SR is and what is it used for?

• 2. What you need to know before you take Securon SR

• 3. How to take Securon SR

• 4. Possible side effects.

• 5. How to store Securon SR

• 6. Contents of the pack and other information

• 1. WHAT SECURON SR IS AND WHAT IS IT USED FOR?

Securon SR tablets belong to a group of medicines called calcium channel blockers.

Calcium channel blockers change the amount of calcium getting into the muscle cells in your heart and blood vessels. This can change the strength and speed with which your heart beats. It also opens up the blood vessels so blood can be pumped around the body more easily. This helps more oxygen to get to your heart muscle and can lower your blood pressure.

Securon SR tablets are used to treat hypertension (high blood pressure) and to prevent angina (chest pain) attacks. The tablets may also be prescribed following a heart attack, to prevent another attack occuring.

The active ingredient in Securon SR tablets is verapamil hydrochloride.

2. what you need to know before you take securon sr

If the answer to any of the following questions is ‘YES’ please tell your doctor or pharmacist BEFORE taking any tablets:

• Are you sensitive (allergic) to verapamil or any of the other ingredients in the tablets? (See Section 6).
• Are you pregnant or planning to become pregnant, or are you breast feeding?
• Do you have very low blood pressure?
• Do you have or have you ever suffered from heart problems such as heart failure?
• Do you have an abnormally slow or irregular heart beat?
• Have you recently had a heart attack?
• Do you have liver or kidney problems?
• Do you have or have you ever suffered from heart problems such as heart failure or the heart condition called Wolff-Parkinson-White syndrome?
• Do you have a condition where the nerve to muscle transmission is affected e.g.

myasthemia gravis, Lambert-Eaton syndrome, advanced Duchenne muscular dystrophy?

• Are you being treated with ivabradine (for heart conditions)?

Taking other medicines. Please tell your doctor or pharmacist if you are taking any medicines with or without a prescription or have recently taken any of the following medicines:

• beta-blockers used to treat high blood pressure and heart conditions (these include atenolol, propranolol and metoprolol)
• alpha blockers used to treat high blood pressure and heart conditions (these include prazosin and terazosin)
• diuretics (also called “water pills”)
• medicines known as “statins” such as atorvastatin, lovastatin, simvastatin used to lower cholesterol levels
• any other medicine for high blood pressure or an abnormal heart beat (arrhythmia) such as quinidine, flecainide, disopyramide, digoxin and digitoxin
• dabigatran (medicine to prevent the formation of blood clots)
• medicines containing ivabradine for the treatment of certain heart diseases
• medicines used to treat depression (including the herbal product St John’s Wort), anxiety or psychosis. These may include imipramine, buspirone and lithium.
• medicines known as immunosuppressants such as ciclosporin, sirolimus, everolimus and tacrolimus. These are used to prevent organ transplant rejection.
• glibenclamide, used to treat certain types of diabetes.
• aspirin, a non-steroidal anti-inflammatory painkiller (NSAID) used to relieve pain and reduce fever
• almotriptan, used to treat migraine
• midazolam, used as a sedative or anaesthetic
• theophylline, used to treat asthma
• doxorubicin, an anti-cancer medicine
• cimetidine, used to treat indigestion or stomach ulcers
• rifampicin, used to treat tuberculosis and other types of infection
• carbamazepine, phenytoin or phenobarbital (phenobarbitone). These medicines are used as anti-convulsants.
• ritonavir, used to treat HIV
• erythromycin, clarithromycin and telithromycin, used to treat types of infection
• colchicine or sulfinpyrazone, used to treat gout.

Tell your surgeon or dentist that you are taking Securon SR if surgery is planned as it may affect the anaesthetic used.

Other important information

Do NOT drink grapefruit juice whilst taking your tablets as it can affect the absorption of this medicine. This does not occur with other fruit juices such as orange, apple or tomato juice.

Drinking alcohol

Securon SR will increase the time your body takes to get rid of alcohol. This means that you may not have to drink as much for your blood alcohol levels to be above the legal limit to drive. It will also take you longer to sober up.

Pregnancy and breast feeding

Please discuss with your doctor if you are pregnant, planning to become pregnant or are breast feeding.

3. how to take securon sr

ALWAYS take this medicine exactly as your doctor has told you. Check with your doctor if you are not sure.

TAKE YOUR TABLETS with a glass of water. You should swallow the tablets without chewing or crushing them. It does not matter if you have not eaten.

Following a heart attack

The usual dose following a heart attack is 360 mg each day. This may be taken as one Securon SR 240 mg tablet in the morning and a Half Securon SR 120 mg tablet in the evening or as one Half Securon SR 120 mg tablet taken three times a day. The doctor will usually wait at least a week after your heart attack before prescribing these tablets.

CHILDREN:

Securon SR is NOT recommended for children under 12 years of age.

Elderly

The dose will be the same as that for adults. If you have kidney or liver problem, your doctor may lower your dose.

If you take more Securon SR than you should

If you take more tablets than prescribed (an overdose) you should contact a doctor or go to the nearest hospital casualty department IMMEDIATELY taking your tablets with you.

If you forget to take Securon SR

If you forget to take your tablets take them as soon as you remember, unless it is almost time for your next dose. If it is, do not take the missed dose at all. Do not take double dose to make up for a forgotten tablet.

If you stop taking Securon SR

If you stop taking your tablets your condition may get worse. It is important that you keep taking these tablets until your doctor tells you to stop. Do NOT stop just because you feel better.

Other things to remember about Securon SR

Securon SR 240 mg tablets may be broken in half if your doctor advises you to do so (e.g. if a lower dose has been prescribed).

• The tablets should NOT be crushed, chewed or sucked, as this will affect the modified-release formulation of the product.

If you have any further questions on the use of this medicine, ask your doctor or pharmacist.

4. possible side effects

As with all medicines, Securon SR can cause side effects, although not everyone will suffer from them. If you experience any other unusual symptoms whilst taking your tablets, tell your doctor or pharmacist.

Tell your doctor IMMEDIATELY if you experience any of the following side effects:

• Yellowing of the skin or eyes, a fever or tenderness around the middle. These are signs that your liver may not be functioning as well as usual
• Palpitations, chest pains for the first time or chest pains becoming more frequent, swollen ankles, hot and painful hands or feet
• Swelling of the limbs
• Unexpected wheezing, difficulty breathing, swelling of the mouth, lips or tongue or severe skin rash.