PHENOXYMETHYLPENICILLIN 250 MG TABLETS - patient leaflet, side effects, dosage

1. WHAT PHENOXYMETHYLPENICILLIN TABLET IS AND WHAT IT IS USED FOR

Phenoxymethyl­penicillin, is an antibiotic, which belongs to a group of medicines called penicillins, which are used to kill bacteria that cause infections in your body.

Each tablet contains 250mg of Phenoxymethyl­penicillin potassium as the active ingredient.

The strength you are given will be decided by your doctor.

Phenoxymethyl­penicillin potassium is used to treat infections caused by bacteria that are sensitive to penicillins. These infections include:

• Infections of the lungs (such as pneumonia and bronchitis)
• Ear and throat infections (such as otitis media and pharyngitis)
• Other infections (such as infections of the skin and soft tissue, respiratory tract, scarlet fever and erysipelas)

Phenoxymethyl­penicillin is also used to prevent infections such as:

• Prevention of recurrent attacks of rheumatic fever or chorea (infection of the nervous system)
• Prevention of lung infections in patients with no spleen or sickle cell disease
• Prevention of pneumococcal infection (e.g. in asplenia)

2. what you need to know before you take phenoxymethylpenicillin tablet

Do not take Phenoxymethyl­penicillin tablet:

• If you have ever had a bad reaction or allergic to any penicillin or cephalosporin antibiotics, or any of the other ingredients listed in section 6
• If you have ever had a skin rash or swelling of the face or neck or shortness of breath when taking any antibiotic

Warnings and precautions

• Talk to your doctor or pharmacist before taking Phenoxymethyl­penicillin tablet Have a history of allergies and/or asthma Have kidney disease
• Have suffered severe diarrhoea following previous treatment with antibiotics and from any stomach problems, e.g. vomiting
• Are feeling or being sick or are suffering from any gut disorder which may affect the way your body absorbs the medicine
• Have a severe illness
• Have history of antibiotic-associated colitis

Other medicines and

Phenoxymethyl­penicillin tablet:

Tell your doctor or pharmacist if you are taking, have recently taken any other medicines even those not prescribed, including herbal and homeopathic remedies or might take any other medicines including:

• Other antibiotics (such as tetracyclines, erythromycin, chloramphenicol, neomycin, sulphonamides, have been reported to reduce the effect of penicillin)
• Sulfinpyrazone or probenecid (used for the treatment of gout

-painful inflammation of the joints)

• Methotrexate (used in the treatment of severe rheumatoid arthritis, severe psoriasis and cancer) and guar gum (used in the treatment of diabetes)
• Anti-coagulants (e.g. warfarin to prevent blood clots)
• Oral typhoid vaccine (penicillin can stop this from working)
• Phenoxymethyl penicillin may interfere with the way the contraceptive pill works. If you are taking the Pill you should use additional precautions (such as a condom or diaphragm) for the cycle during which you took the antibiotic

Phenoxymethyl­penicillin tablet with food and drink

Guar gum (used as a thickening agent and normally found in puddings and ice-cream and benefiber) can reduce the absorption of phenoxymethyl penicillin.

Pregnancy and breast-feeding:

If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.

Driving and using machines

This medicine should not affect your ability to drive or to use machinery.

Phenoxymethyl­penicillin contains lactose Patients with rare hereditary problems of fructose intolerance, gluclose-galactose malabsorption or sucrose-isomaltase insufficiency should not take this medicine. If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicinal product.

3. how to take phenoxymethylpenicillin tablet

Always take this medicine exactly as your doctor or pharmacist has told you. Check with your doctor or pharmacist, if you are not sure. The dosage prescribed will depend upon the type and severity of the infection. In general the treatment must be continued 2–3 days after improvement of the symptoms. It is important that you complete the entire course of medicine your doctor has prescribed for you.

Treatment of Infection

Adults: 250–500mg every 6 hours or as , directed by your doctor.

Child 1–5 years of age: 125mg every 6 hours.

Child 6–12 years of age: 250mg every 6 hours or as directed by your doctor.

Prevention of Infection

Rheumatic fever: 250mg twice daily..

Lung infection in patients with no spleen or sickle cell disease:

Adults: 500mg every 12 hours.

Child aged 6–12 years: 250mg every 12 hours.

Child under 5 years: 125mg every 12 hours. If you have kidney damage your doctor may give you a different dose. Dosage might be changed by your doctor if you have liver problems along with kidney problem.

When to take your medicine

Phenoxymethyl­penicillin contains lactose tablet is usually prescribed to be taken four times a day. It is best to take it as evenly spaced as possible. Take this medicine when your stomach is empty. You should swallow this medicine about half an hour before meals.

If you take more Phenoxymethyl­penicillin tablet than you should

If you accidentally take too much medicine, contact your doctor or pharmacist who will recommend what action you should take.

If you forget to take Phenoxymethyl­penicillin tablet

If you forget to take your medicine take it as soon as you remember.

Do not take a double dose to make up for a forgotten dose.

If you or a child ever takes too much medicine contact your doctor or local casualty department immediately. Take any remaining tablets and this leaflet to show to your doctor.

If you stop taking

Phenoxymethyl­penicillin Tablet

Keep taking this medicine until your doctor tells you to stop.

Do not stop taking the tablets if you feel better, as your infection may come back or get worse.

If you have any further questions on the use of this medicine, ask your doctor or pharmacist.

4. possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.

Phenoxymethyl­penicillin potassium is generally well tolerated.

Occasionally soft stools occur but this does not require interruption of treatment.

However, if you develop severe diarrhoea, which may contain blood, you should contact your doctor immediately.

STOP taking the medicine and tell your doctor IMMEDIATELY if you experience any of the following:

• Feeling or being sick is a rare reaction
• Allergic reactions can occur, which may rarely be severe.

Stop taking the mixture and contact a doctor immediately if you notice skin rash or itching, hives, which may be itchy raised or red, fever, chills, joint pains, swelling of the face, lips, throat or tongue, breathing difficulties or dizziness. Allergic reactions may also include affects on the blood and kidney

• Effects on the nervous system occur rarely and are more likely if you have an injection of an antibiotic or have severe kidney damage. If you experience numbness or tingling of the hands or feet, or fits, you should see your doctor
• Profuse watery diarrhoea usually with blood (pseudomembranous colitis) and mucus, stomach pain and fever
• unusual bleeding or bruising
• seizures
• peeling/blistering of the skin
• Serum sickness-like reactions (characterised by fever, chills, joint pains and oedema)
• Kidney problems, which might cause blood in the urine or reduced amounts of urine
• Jaundice – yellowing of skin or whites of the eyes
• Convulsions

Tell your doctor or pharmacist if you notice any of the following and they worry you.

• Stomach pain or cramps, nausea (feeling sick), vomiting (being sick) and diarrhoea
• Sore mouth
• Hepatitis
• Black hairy tongue
• Pins and needles or numbness
• Sore throats, infections, or fever (may be caused by low white blood cells)
• Problems with blood clotting (unusual bleeding or bruising)
• Anaemia (may cause lack of energy or tiredness)
• Thrush (a yeast infection of the vagina, mouth or skin folds)

5. how to store phenoxymethylpenicillin tablet

Keep this medicine out of the sight and reach of children.

Expiry date

Do not use this medicine after the expiry date which is stated on the carton.

The expiry date refers to the last day of that month.

Storage conditions: Do not store above 25°C. Store in original package. Keep the container tightly closed.

If your doctor decides to stop the treatment, return any tablets left over the pharmacist. Only keep them if your doctor tells you to. Do not use this medicine if you notice visible signs of deterioration. Do not throw away any medicines via wastewater or household waste. Ask your Pharmacist how to throw away medicines you no longer use. These measures will help protect the environment.

Important reminder: Do not give your medicine to anyone else, even if they suffer from the same condition as you. This medicine could be harmful to them or interfere with other treatments. Your medicine has been prescribed by your doctor specifically for you.

6. contents of the pack and other information

What Phenoxymethyl­penicillin tablet contains:

Active ingredient: Each tablet contains 250mg of phenoxymethyl­penicillin as phenoxymethyl­penicillin potassium. The Other ingredients are: lactose, talc, magnesium stearate and starch.

What Phenoxymethylpenicillin tablet looks like and contents of the pack

Phenoxymethyl­penicillin Potassium tablets are shiny white, flat tablets with bevel edge and embossed with ‚K‘ on one side and breakline on the other and come in bottles of 100, 500 and 1000 tablets and blister packs of 28 and 504 tablets.

Marketing Authorization Holder Flamingo Pharma (UK) Ltd.

1st Floor, Kirkland House, 11–15 Peterborough Road, Harrow, Middlesex, HA1 2AX, United Kingdom.

Manufacturer

Flamingo Pharma (UK) Limited

The Bloc,

38 Springfield Way,

Anlaby, Hull,

HU10 6RJ, United Kingdom

Product licence number PL 43461/0073

For any information about this medicine, please contact the Marketing Authorisation Holder.

The Leaflet was last reviewed in January 2021.

If you would like this leaflet in a different format, please contact the licence holder at the above address

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