PENBRITIN SYRUP 125 MG / 5ML, AMPICILLIN 125 MG / 5ML POWDER FOR ORAL SUSPENSION - patient leaflet, side effects, dosage

3. How to take

4. Possible side effects

5. How to store

• 6. Further information

1. what this medicine is and what it is used for

Ampicillin suspension contains ampicillin which belongs to the penicillin group of antibiotics.

Ampicillin works by killing bacteria that cause infections such as:

• ear, nose and throat infections
• bronchitis, pneumonia, chest infections
• urinary tract infections
• sexually transmitted infections
• skin and soft tissue infections
• gastrointestinal infections
• blood poisoning.

• 2. Before you take

Do NOT take Ampicillin suspension if you:

• are allergic to ampicillin, other antibiotics called beta-lactams (e.g. penicillin or cephalosporin) or any of the other ingredients (see Section 6).

If this applies to you, speak to your doctor or pharmacist.

Take special care with Ampicillin suspension

Before taking the suspension, tell your doctor if you:

• have ever had a skin rash or swelling of the face or neck when taking any antibiotic
• are already being treated with another antibiotic
• have glandular fever or low immune system
• have leukaemia
• have kidney problems.

Taking other medicines

Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription, and herbal preparations.

Some medicines may be affected by Ampicillin or they may affect how well Ampicillin will work. Tell your doctor or pharmacist if you are taking:

• any other antibiotics
• allopurinol or probenecid for conditions such as gout
• oral contraceptives (the pill).. You will need an additional method of contraception, such as condoms. Speak to your doctor or pharmacist about how long you need to take extra precautions for.

Urine tests: Tell the doctor if you are having urine tests for glucose, as your medicine may affect the results.

Pregnancy and breast-feeding

Ampicillin will not harm your unborn baby. Small quantities of the medicine may be prese nt in breast milk.

Ask your doctor for advice before taking any medic ine.

Driving and using machines

Ampicillin suspension is unlikely to affect your ability to operate machinery or to drive.

Important information about some of the ingredients of Ampicillin suspension

• sodium

Each 5 ml Ampicillin suspension contains 16.7 mg of sodium.

This should be taken into consideration by patients on a controlled sodium diet.

• sucrose

If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicine.

Each 5 ml Ampicillin suspension contains 3.6 g sucrose. This should be taken into account in patients with diabetes mellitus.

3. how to take

Always take Ampicillin suspension exactly as your doctor has told you and always read the label. Your doctor will decide on the appropriate dose to suit your condition.

Ask your doctor or pharmacist if you are not sure.

• Shake the bottle before taking the medicine.
• Take the suspension, half an hour to one hour before food.
• After taking Ampicillin suspension, rinse the mouth -the suspension contains sucrose which may be harmful to the teeth if the suspension is taken for more than 2 weeks.
• Space the doses as evenly as possible through the day – for example before meal times and at bedtime.

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Doses

Adults and children over 10 years: the usual dose is 250 mg to 750 mg four times a day.

Children under 10 years: half the adult dose four times a day.

In severe infections the above doses may be increased by your doctor.

Patients with kidney problems: if your kidneys are not working very well, your doctor may change the dose.

Your doctor will give you special instructions if you are on kidney dialysis.

If you take more than you should

If you take more suspension than you should you may get nausea, vomiting and diarrhoea.

• 1. Tell your doctor, pharmacist or nearest hospital casualty department immediately.

• 2. Take the bottle and any remaining suspension with you so that people can see what you have taken.

• 3. Do this even if you feel well.

If you forget to take

If you forget to take a dose take it as soon as you remember, but i f it is almost time for your next dose, skip the missed dose and continue as usual.

Do not take a double dose to make up for a missed dose.

If you stop taking

Do not stop just because you feel better. If you stop too soon, the infection may come back.

Keep taking your suspension until the prescribed course is finished.

If you have any f urther questions on the use of this product, ask your doctor or pharmacist.

4. possible side effects

Like all medicines, Ampicillin suspension can cause side effects, although not everybody gets them. Do not be

alarmed by this list of possible side effects. You may not experience any of them.

STOP taking the suspension and seek medical help immediately if you have any of the following allergic reactions:

• difficulty breathing or swallowing, swelling of the face, lips, tongue or throat
• severe itching of the skin, with a red rash or raised lumps
• blistering of the mouth, eyes, or genital region, patchy areas of rash, peeling skin.

Seek immediate medical attention if you have any of the following rare symptoms:

• severe stomach cramps, watery and severe diarrhoea which may be bloody, fever
• yellowing of your skin or eyes, pale faeces and dark urine, unexplained persistent nausea, stomach problems, loss of appetite or unusual tiredness

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• unusual bleeding or bruising
• fever, sore throat, mouth ulcers, repeated infections or infections that will not go away
• feeling tired, breathless, and looking pale
• fever, rash, nausea, aches and pains, passing more or less urine than usual or passing urine at night.

Some of these reactions may happen several weeks after finishing the treatment.

The following side effects usually settle without changing the dose:

• upset stomach, nausea or diarrhoea.

Blood tests: Tell your doctor if you are having blood tests as your medicine can cause short-term changes in blood cell counts.

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5. how to store

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• 6. Further information

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