Patient leaflet - PANADOL EXTRA ADVANCE 500 MG / 65 MG TABLETS
Extra Advance 500 mg/65 mg Tablets
Paracetamol + Caffeine
Please read right through this leaflet before you start using this medicine. This medicine is available without prescription, but you still need to use Panadol Extra Advance Tablets carefully to get the best results from
th them.
- Keep this leaflet, you may need to read it again.
- If you have any questions, or if there is anything you do not understand, ask your pharmacist.
- Contains Paracetamol.
In this leaflet:
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1. What Panadol Extra Advance Tablets do
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2. Check before you take Panadol Extra Advance Tablets
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3. How to take Panadol Extra Advance Tablets
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4. Possible side effects
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5. How to store Panadol Extra Advance Tablets
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6. Further information
1. What Panadol Extra Advance Tablets do
to treat pain, fever, symptoms of cold and flu, or to aid sleep.
Ask your doctor before you take this medicine:
- if you have liver or kidney problems
- if you are underweight or malnourished
- if you regularly drink alcohol
- if you have a severe infection as this may increase the risk of metabolic acidosis.
Signs of metabolic acidosis include:
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– deep, rapid, difficult breathing
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– feeling sick (nausea), being sick (vomiting)
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– loss of appetite
Contact a doctor immediately if you get a combination of these symptoms. You may need to avoid using this product altogether or limit the amount of paracetamol that you take.
If you are taking other medicines
Talkto your doctor or pharmacist before taking these tablets if you are taking any prescribed medicines; particularly metoclopramide or domperidone (for nausea [feeling sick] or vomiting [being sick]) or colestyramine (to lower blood cholesterol ). If you take blood thinning drugs (anticoagulants e.g. warfarin ) and you need to take a pain reliever on a daily basis, talk to your
Swallow 2 tablets every
4 hours as needed. Do not take more than 8 tablets in 24 hours.
Children aged 12–15 years:
Swallow 1 tablet every 4 hours as needed. Do not give more than 4 tablets in 24 hours.
Do not take more frequently than every 4 hours.
- Do not take more than the recommended dose.
- Do not give to children under 12 years.
- Avoid too much caffeine in drinks like coffee and tea.
High caffeine intake can cause difficulty sleeping, shaking and an uncomfortable feeling in the chest. If your symptoms continue or your headache becomes persistent, see your doctor.
If you take too many tablets
Talk to a doctor at once if you take too much of this medicine even if you feel well. This is because too much paracetamol can cause delayed, serious liver damage.
4. possible side effects
Like all medicines, Panadol Extra Advance Tablets can have side effects but not everybody gets them. A small number of people have had side effects. Very rare cases of serious skin reactions have been reported.
Stop taking the medicine and tell your doctor immediately if you experience:
- Allergic reactions which may be severe such as skin rash and itching sometimes with swelling of the mouth or face or shortness of breath
- Skin rash or peeling, or mouth ulcers
- Breathing problems. These are more likely if you have experienced them before when taking other painkillers such as ibuprofen and aspirin
- Unexplained bruising or bleeding side effects directly via the Yellow Card Scheme at or search for MHRA Yellow Card in the Google Play or Apple App Store. By reporting side effects, you can help provide more information on the safety of this medicine.
5. how to store panadol extra advance tablets
Keep out of the sight and reach of children.
Do not use this medicine after the ‘EXP’ date shown on the pack.
Store below 25°C.
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6. Further information