Patient leaflet - Nefopam Hydrochloride 30 mg film-coated tablets
1. What Nefopam Hydrochloride Tablets is and what it is used for
Nefopam Hydrochloride Tablets belongs to a group of medicines called analgesics, commonly known as pain killers or pain relievers. The active substance, nefopam hydrochloride, interrupts the pain messages being sent to your brain, and it also acts in your brain to stop pain messages being felt.
This means that Nefopam does not stop the pain from happening, but you will not be able to feel the pain as much. Nefopam Hydrochloride Tablets is used to relieve of acute and chronic pain (for example pain after an operation, dental pain, joint or muscle pain, after an injury, or pain caused by cancer). Nefopam Hydrochloride Tablets should not be used to treat the pain from a heart attack.
2. What you need to know before you take Nefopam Hydrochloride Tablets
Do not take Nefopam Hydrochloride Tablets if:
You are a child under 12 years old
You have ever had an allergic reaction to nefopam
hydrochloride or any of the ingredients resulting in a skin rash, swelling of the face or difficulty in breathing (see section 6. Contents of the pack and other information)
You are taking monoamine oxidase inhibitors (MAOIs)
to treat your depression
- You have, or have ever had, epilepsy (fits).
Warnings and precautions
If the answer to any of the following is ‘yes’, you must tell your doctor - your doctor may decide to alter your treatment.
- Are you pregnant or breast feeding?
Do you have severe problems with your liver or
kidneys?
- Do you have, or have you had in the past difficulty passing urine?
- Are you taking other medicines?
Have you previously been diagnosed with glaucoma
(increased pressure in the eye)?
Use of Nefopam Hydrochloride Tablets may lead to dependence and abuse. If you have concerns that you may become dependent on Nefopam Hydrochloride Tablets, it is important that you consult your doctor.
Other medicines and Nefopam Hydrochloride Tablets
Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines, including those obtained without prescription and medicines listed below:
- Monoamine oxidase inhibitors (known as MAOIs) for depression.
- Tricyclic antidepressants for depression
- Anticholinergics
- Sympathomimetic
Pregnancy and breast-feeding
Nefopam Hydrochloride Tablets should not be taken during pregnancy or while breast-feeding.
If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine. Please contact your doctor if you become pregnant during your treatment.
Driving and using machines
Nefopam Hydrochloride Tablets can cause drowsiness. Do not drive or operate heavy machinery unless you know how Nefopam Hydrochloride Tablets affects you.
3. How to take Nefopam Hydrochloride Tablets
Always take this medicine exactly as your doctor or pharmacist has told you. Check with your doctor or pharmacist if you are not sure.
The recommended dose is two tablets taken three times a day. Your doctor may increase this dose up to a maximum of three tablets taken three times a day according to your needs.
Ask your doctor or pharmacist if:
- You are not sure how many tablets to take or when to take them
- You think the effect is too strong or too weak
- Swallow your tablets with water.
Use in adolescents and children:
Over 12 years - as per adults (see above).
Under 12 years - Nefopam 30mg Tablets should not be taken by children under 12.
Dosage for elderly patients:
In older patients the doctor may reduce the number of tablets that are taken.
Dosage for patients with kidney and/or liver problems:
Your doctor may adjust the dose of Nefopam Hydrochloride Tablets depending upon your condition.
If you take more Nefopam Hydrochloride Tablets than you should
If you accidentally take more tablets than your prescribed dose, tell your doctor or pharmacist immediately and if necessary contact your nearest hospital casualty
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POM
Marketing Authorisation Holder and Manufacturer:
MEDREICH PLC
Warwick House, Plane Tree Crescent,
Feltham TW13 7HF, UK
E-mail: info@medreich.co.uk
This leaflet was last revised in March 2026
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department. Remember to take the pack and any remaining medicines with you.
If you forget to take Nefopam Hydrochloride Tablets
If you forget to take Nefopam Hydrochloride Tablets, take it as soon as you remember. Do not take more than one dose at the same time to make up for the forgotten dose.
If you stop taking Nefopam Hydrochloride Tablets
Do not stop taking Nefopam Hydrochloride Tablets without first checking with your doctor.
If you have any further questions on the use of this medicine, ask your doctor or pharmacist.
4. Possible side effects
Like all medicines Nefopam Hydrochloride Tablets can cause side effects, although not everybody gets them.
Please stop taking this medicine and contact your doctor as soon as possible if you experience the following rare reactions:
swelling of the skin and soft tissue around the eyes, nose
and throat (angioedema), or allergic reactions (anaphylaxis).
Other side effects include:
Rare (may affect up to 1 in 1,000 people)
becoming dependent on Nefopam Hydrochloride
Tablets (drug dependence).
Not known (frequency cannot be estimated from the available data)
- feeling sick
- feeling light-headed, dizzy or nervous, or fainting
- decrease in blood pressure
- numbness or tingling in the extremities
- dry mouth
- having difficulty passing urine
- convulsions, tremor
- confusion
- hallucinations (seeing things that aren’t there).
- being sick
- abdominal pain or diarrhoea
- blurred vision
- drowsiness
- sweating
- trouble sleeping
- headaches
awareness of your heartbeat (palpitations), or a fast
heartbeat (tachycardia).
Reporting of side effects
If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Yellow Card Scheme at: www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store. By reporting side effects you can help provide more information on the safety of this medicine.
5. How to store Nefopam Tablet
- Keep this medicine out of sight and reach of children.
Do not use this medicine after the expiry date which is
stated on the carton and blister. The expiry date refers to the last day of that month.
This medicine does not require any special storage
conditions.
Do not throw away any medicines via wastewater or
households waste. Ask you pharmacist how to throw away medicines you no longer use. These measures will help protect the environment.
6. Contents of the pack and other information
What Nefopam Hydrochloride Tablets contains
The active substance is nefopam hydrochloride. Each tablet contains 30 mg of nefopam hydrochloride.
The other ingredients are:
Core Tablet: Microcrystalline cellulose (E460), calcium hydrogen phosphate dihydrate (E341), colloidal anhydrous silica, pregelatinised starch, hydrogenated vegetable oil, magnesium stearate.
Film-coating: hypromellose, titanium dioxide and macrogol.
What Nefopam Hydrochloride Tablets looks like and contents of the pack
White to off white coloured, round, bevel edged, film-coated tablets debossed with ‘N 30’ on one side and plain on other side.
Nefopam 30 mg tablets are available in Alu-PVC blisters of 90 tablets.
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