Patient leaflet - Medomon XL 60 mg prolonged-release tablets
1. What Medomon XL Tablets are and what are they used for
Medomon XL Tablets contains a medicine called isosorbide mononitrate. This belongs to a group of medicines called ‘nitrates’.
- It is used to prevent chest pain (angina).
It works by making the blood vessels relax and widen. This makes it easier for the heart
to pump blood around the body.
2. Before you take Medomon XL Tablets
Do not take Medomon XL Tablets if you:
are allergic (hypersensitive) to isosorbide mono nitrate or any of the other ingredients in
suffer from a condition called constrictive pericarditis (inflammation of the lining around
the heart), or cardiac tamponade (where the fluid around the heart puts pressure on the heart).
- are having a heart attack (acute myocardial infarction)
- suffer from very low blood pressure (hypotension)
suffer from a condition called aortic stenosis (narrowing of the main artery coming from
the heart).
suffer from a condition called mitral stenosis (narrowing of the mitral valve on the left
side of the heart)
suffer from a condition called hypertrophic cardiomyopathy (a heart disease which
causes the heart muscle to become thick and can cause symptoms such as chest pain, dizziness and collapse).
suffer from a condition which can increase the pressure on the brain e.g. a recent
serious head injury and bleeding into the brain (cerebral haemorrhage)
- suffer from severe anaemia (reduction in the number of red blood cells)
suffer from closed angle glaucoma (a condition which can causes sudden attacks of
eye pain due to rapid increases in eye pressure, with symptoms such as blurred vision, painful red eye and headache)
are taking any medicines for erectile problems, such as Viagra (Sildenafil), which
belong to a group of medicines called phosphodiesterase type 5 inhibitors (see section on Interaction with other medicines).
- are in the first three months of pregnancy
Do not take Medomon XL Tablets if any of the above apply to you. If you are not sure, talk to your doctor or pharmacist before taking Medomon XL Tablets.
Warnings and precautions
Talk to your doctor or pharmacist before taking Medomon XL Tablets if you:
- have had any serious damage to your heart, such as a heart attack or operation
- suffer from liver or kidney disease
- suffer from hypothyroidism (underactive thyroid gland)
- suffer from hypothermia (very low body temperature)
- suffer from malnutrition (severe lack of food)
drink alcohol - alcohol should be avoided during treatment with Medomon XL Tablets If any of the above apply to you, or you are not sure, talk to your doctor or pharmacist before taking Medomon XL Tablets.
Reminder
This medicine should not be used to treat a sudden angina attack. Your doctor should prescribe (GTN) glyceryl trinitrate (tablets or spray) if you have a sudden angina attack. Medomon XL Tablets is used to prevent attacks of angina, and should be used regularly, as prescribed by the doctor.
other medicines
Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines. This includes medicines that you buy without a prescription and herbal medi-cines. This is because Medomon XL Tablets can affect the way some medicines work and some medicines can have an effect on Medomon XL Tablets.
Do not take Medomon XL Tablets if you are taking the following medicines:
- medicines which reduce blood pressure such as:
o ACE inhibitors, e.g. enalapril, captopril
o beta-blockers, e.g. atenolol, propranolol
o calcium channel blockers, e.g. diltiazem, verapamil, nifedipine
o angiotensin II receptor antagonists, e.g. candesartan
o phosphodiesterase Type 5 Inhibitors e.g. sildenafil
o alprostadil used to treat erectile dysfunction
o aldesleukin used to treat kidney cancer and melanoma
- benzodiazepines, e.g. temazepam
- tricyclic antidepressants, e.g. amitriptyline.
Pregnancy and breast-feeding
Ask your doctor for advice before taking Medomon XL Tablets if you are pregnant, planning to become pregnant or are breast-feeding.
Driving and using machines
You may experience dizziness when you start taking Medomon XL Tablets. You should therefore know how you react to Medomon XL Tablets before you drive or use machines.
Important information about some of the ingredients of Medomon XL Tablets
These tablets contain lactose. Consult your doctor if you have been told you have an intolerance to some sugars before taking these tablets.
Manufacturer:
Rudipharm Limited
Oak House, Reeds Crescent, Watford, WD24 4QP, UK
To listen to or request a copy of this leaflet in Braille, large print or audio please call, +44 (0) 1293 827819 (UK only) Please be ready to give the following information: Product name: Reference number: Medomon XL 60mg PL 49565/0025
Prolonged Release Tablets
This leaflet was last revised in March 2026.
Marketing Authorisation Holder:
Rudipharm Limited
Unit 6, Salbrook Road Industrial Estate
Salbrook Road, Redhill, Surrey RH1 5GJ, UK
3. How to take Medomon XL Tablets
Always take Medomon XL Tablets exactly as your doctor has told you. You should check with your doctor or pharmacist if you are not sure.
- Swallow the tablets whole or broken in half (if this is easier to swallow).
- Take the tablets with half a glass of water
- Do not crush or chew the tablet
Dosage:
Adults: One tablet to be taken once daily in the morning. This may be increased to two tablets on the advice of your doctor, in which case both tablets should be taken once daily in the morning.
Treatment is sometimes started for the first 2-4 days, with half a tablet once daily in the morning in order to minimise the possibility of headache.
Elderly: The usual dose is the same as the adult dose.
Children:
Not recommended for use in children.
You must not take Medomon XL Tablets for a sudden attack of angina. If you have a sudden attack, take a glyceryl trinitrate tablet (follow the instructions given on the label). Very occasionally, some people see the remains of the tablet in their bowel motions. This is quite normal and does not mean that the medicine has not been released.
If you take more Medomon XL Tablets than you should
If you (or someone else) swallow a lot of tablets at the same time, or you think a child has swallowed any of these tablets, contact your nearest hospital casualty department or your doctor immediately. Take this leaflet and your tablets with you. The symptoms of an overdose may be pulsing headache, reddening of the skin, cold perspiration, nausea, vomiting and a fast heartbeat.
If you forget to take Medomon XL Tablets
If you forget to take your tablet(s) but remember within 12 hours of the usual time, take it when you remember. If you remember more than 12 hours after your usual time, don't take the tablet and just carry on with the next dose when it is due.
If you stop taking Medomon XL Tablets
Do not stop taking your tablets without first discussing this with your doctor as this may be harmful.
If you have any further questions on the use of this medicine, ask your doctor or pharmacist.
4. Possible side effects
Like all medicines, Medomon XL Tablets can cause side effects, although not everybody gets them.
The following side effects may happen with this medicine:
- Headache
- Feeling sick (nausea)
- Feeling dizzy
The above problem usually disappears with time.
Other possible side effects:
Common (may affect up to 1 in 10 people)
- Low blood pressure (this may make you feel faint or dizzy)
- Faster heartbeat (tachycardia)
Headache
- Feeling dizzy
- Feeling sick (nausea)
Uncommon (may affect up to 1 in 100 people)
- Being sick (vomiting)
- Diarrhoea
Rare (may affect up to 1 in 1,000 people)
- Fainting
- Rash
- Itchy skin
Very rare (may affect up to 1 in 10,000 people)
- Pain in muscles
Reporting of side effects
If you get any side effects, talk to your doctor or pharmacists. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Yellow card Scheme: www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store. By reporting side affects you can help provide more information on the safety of this medicine.
5. How to store Medomon XL Tablets
Keep out of the reach and sight of children.
Store your tablets in the original package.
Do not store above 25°C
Do not use your medicine after the expiry date shown on the label.
Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.
6. Further information What Medomon XL Tablets contain
Each tablet contains 60mg of the active ingredient isosorbide -5-mononitrate. The other substances are lactose monohydrate, hypromellose, maize starch, glyceryl palmitostearate and magnesium stearate.
What Medomon XL Tablets looks like and contents of the pack
The tablets are white, capsule shaped, biconvex and uncoated with scoring. They are supplied in cartons containing two strips of blister packs - each strip containing 14 tablets (28 tablets per carton).
Medomon XL Tablets - 60 mg
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