Medicines by ATC code L01CE Topoisomerase 1 (TOP1) inhibitors

ATC group of level 4 – chemical subgroup · in plain English: cancer medicines

This site has the patient leaflet or the SPC of 17 medicines in this group and its subgroups.

2 prescription only (POM)
2 no longer supplied or not available

Place in the ATC classification

L Antineoplastic and immunomodulating agents 1,791 medicines
1. L01 Antineoplastic agents 1,025 medicines
  1. L01C Plant alkaloids and other natural products, antineoplastic drugs 97 medicines
    1. L01CE Topoisomerase 1 (TOP1) inhibitors 17 medicines
      1. L01CE01 topotecan 9 medicines
      2. L01CE02 irinotecan 8 medicines

2 more subgroups have no medicine with a leaflet on this site.

Active substances in the group

Irinotecan 6 medicines
Irinotecan anhydrous free-base 1 medicine
Irinotecan pegylated liposomal 1 medicine
Topotecan 9 medicines

Medicines in the group and its subgroups

Medicine	Legal category
Campto 40 mg / 2 ml concentrate for solution for infusion SPC (L01CE02 irinotecan)	–
Hycamtin 0.25 mg hard capsules SPC no longer supplied (L01CE01 topotecan)	–
Hycamtin 1 mg hard capsules SPC (L01CE01 topotecan)	Prescription only (POM)
Hycamtin 1 mg powder for concentrate for solution for infusion SPC no longer supplied (L01CE01 topotecan)	–
Irinotecan 1.5 mg / ml solution for infusion SPC (L01CE02 irinotecan)	–
Irinotecan 20 mg / ml concentrate for solution for infusion (L01CE02 irinotecan)	–
Irinotecan Hydrochloide 20 mg / ml concentrate for solution for infusion SPC (L01CE02 irinotecan)	–
Irinotecan Hydrochloride 20 mg / ml concentrate for solution for infusion SPC (L01CE02 irinotecan)	–
Irinotecan Hydrochloride Medac 20 mg / ml concentrate for solution for infusion SPC (L01CE02 irinotecan)	–
Onivyde pegylated liposomal (previously known as Onivyde) SPC (L01CE02 irinotecan)	–
Onivyde Pegylated liposomal 4.3 mg / ml concentrate for Dispersion for infusion SPC (L01CE02 irinotecan)	Prescription only (POM)
Topotecan 1 mg/ml concentrate for solution for infusion SPC (L01CE01 topotecan)	–
Topotecan Accord Healthcare 1 mg powder for concentrate for solution for infusion SPC (L01CE01 topotecan)	–
Topotecan Accord Healthcare 4 mg powder for concentrate for solution for infusion (L01CE01 topotecan)	–
Topotecan Hospira 4 mg/4 ml - concentrate for solution for infusion (L01CE01 topotecan)	–
Topotecan Medac 1 mg / ml concentrate for solution for infusion SPC (L01CE01 topotecan)	–
Topotecan Sandoz 1 mg/ml concentrate for solution for infusion SPC (L01CE01 topotecan)	–

Other groups of the same level

L01CA Vinca alkaloids and analogues, antineoplastic 18 medicines
L01CB Podophyllotoxin derivatives, antineoplastic drugs 7 medicines
L01CD Taxanes, antineoplastic 50 medicines
L01CX Other plant alkaloids and natural products 5 medicines

Other names of the ATC group

German: L01CE Topoisomerase-I (TOP-I)-Inhibitoren
German: L01CE Topoisomerase-I (TOP-I)-Inhibitoren
Italian: L01CE Inibitori della topoisomerasi
Turkish: L01CE Topoizomeraz 1 (TOP1) inhibitörleri
Czech: L01CE Inhibitory topoizomerázy I (TOP I)

Sources

Patient leaflets and SPCs: the MHRA product information (products.mhra.gov.uk) and the European Medicines Agency (EMA)
Active substances, ATC codes and legal categories: the NHS Dictionary of Medicines and Devices (dm+d), NHS Business Services Authority
World Health Organization (WHO): ATC/DDD classification, group L01CE

Contains public sector information licensed under the Open Government Licence v3.0.

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