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Medical Carbon Dioxide – patient leaflet, side effects, dosage

Text from the MHRA, as of · About this document

Medicine status: Pharmacy medicine (P) Details

Medicine strength:
1 ml/ml
Contains active substance:
Similar medicines:

Patient leaflet - Medical Carbon Dioxide

1. WHAT MEDICAL CARBON DIOXIDE IS AND WHAT IS IT USED FOR

Medical Carbon Dioxide is a liquefied medicinal gas, supplied in cylinders filled to a high pressure. Medical Carbon Dioxide may be used in the following situations:

  • to expand the blood vessels if required • to stimulate breathing after a period of non-breathing
  • to increase Carbon Dioxide levels after a period of rapid breathing
  • during bodily investigations
  • to inflate body cavities during surgery (such as key-hole surgery)
  • in solid form (dry ice) for freezing of tissue and removal of warts.

If Medical Carbon Dioxide is given to you to breathe, it will always be given to you with Medical Oxygen.

2. THINGS TO CONSIDER BEFORE USE

Medical Carbon Dioxide is only given to you in a hospital or clinic under the supervision of a healthcare professional. Ensure that your healthcare professional is aware of any medical conditions that you may have.

Do not use Medical Carbon Dioxide:

  • if your blood or tissues are high in acid • if you have obstructive lung disease such as

    chronic bronchitis or emphysema because it can increase breathing difficulties

Carbon Dioxide should not be used during resuscitation

Taking other medicines

Medical Carbon Dioxide can affect other medicines in the body, including those taken for treating high blood pressure and muscle relaxants.

Medical Carbon Dioxide should not be used with adrenaline or similar drugs.

Tell your healthcare professional if you are taking or have recently taken any other medicines, including medicines obtained without a prescription.

Pregnancy and breast feeding

The use of Medical Carbon Dioxide is not recommended during pregnancy. Medical Carbon Dioxide will not affect you or your baby if used during breast-feeding.

Driving and using machines

You may drive and use machines after using Medical Carbon Dioxide providing that your healthcare professional considers that you are both fit and capable.

3. HOW TO USE MEDICALCARBON DIOXIDE

Instructions for use

Your healthcare professional will ensure that your Medical Carbon Dioxide supply is suitable for your use and that the equipment has been set up correctly so that you receive the right amount of gas.

When you are given your Medical Carbon Dioxide to breathe as a mixture with other medical gases, it will be supplied via a facemask, mouthpiece or endotracheal tube (which is placed down your airways).

Special medical equipment will be used if it is being used to inflate parts of your body during keyhole surgery or gynaecological procedures.

If you have any further questions on how this product is used, ask your healthcare professional.

If you use more Medical Carbon Dioxide than you should

When Medical Carbon Dioxide is supplied at concentrations higher than 5%, it may cause extreme breathing difficulties, raised blood pressure, cause nausea and vomiting and occasionally unconsciousness.

In the event of an overdose your healthcare professional will stop administration and continue appropriate care.

If you have any further questions on the use of this product, ask your healthcare professional.

4. POSSIBLE SIDE EFFECTS

Like all medicines, Medical Carbon Dioxide may cause side effects, although not everyone will get them.

The side effects which may occur are:

  • breathing difficulties, raised blood pressure and

    sickness if administered in concentrations over 5%

  • dizziness if administered in concentrations

    above 8%

  • unconsciousness if administered in

    concentrations above 12.5%.

Less common side effects which may occur are: • heart rhythm problems, when high levels

of Carbon Dioxide enter the blood during laparoscopy

  • heart attacks due to gas bubbles in the

    bloodstream.

Reporting of side effects

If you experience any of these side effects, or if you notice any side effects not listed in this leaflet, contact your healthcare professional immediately. You can also report side effects directly to the Medicines and Healthcare Products Regulatory Agency (MHRA) via the Yellow Card Scheme www. mhra.gov.uk/yellowcard and to BOC Healthcare. By reporting side effects you can help provide more information on the safety of this medicine.

5. HOW TO STORE COMPRESSED MEDICAL OXYGEN CYLINDERS

Expiry date

Medical Carbon Dioxide should not be used after the expiry date stated on the batch label on the cylinder.

Product should be used in strict rotation so that cylinders with the earliest expiry date are used first

Cylinder storage

Cylinders should be securely stored, in a well ventilated, dry and clean area, away from oils, greases, flammable materials and sources of extreme temperature.

The healthcare professional in the hospital or clinic will be responsible for making sure the cylinders are stored correctly.

DO NOT SMOKE or have a naked flame near your Carbon Dioxide gas cylinder.

NEVER se oil based moisturising creams with your cylinder equipment.

6. FURTHER INFORMATION

What Medical Carbon Dioxide contains: Your Medical Carbon Dioxide cylinder contains a minimum of 99.5% (min) Carbon Dioxide. There are no other ingredients.

Medical Carbon Dioxide cylinders

Medical Carbon Dioxide is supplied in the following size cylinders:

Cylinder Size Cylinder Contents

(Litres)

C 450

E 1800

LF 3600

VF 3600

The colour coding of the shoulder of Medical

Carbon Dioxide cylinders is grey. The body is colour coded white.

For a limited period cylinders may have a grey

body.

Shoulder of cylinders viewed from above

Body of cylinder types viewed from the side

All cylinders require separate pressure regulators to be fitted to the cylinder valve before use

Marketing Authorisation Holder and Manufacturer BOC Limited

Forge

43 Church Street West

Woking

Surrey

GU21 6HT

Tel 0800 111 333

bochealthcare-uk@boc.com

bochealthcare.co.uk

This leaflet was last approved in

BOC Healthcare

Customer Service Centre, Priestley Road, Worsley, Manchester M28 2UT, United Kingdom Tel 0800 111 333, Fax 0800 111 555, bochealthcare-uk@boc.com, bochealthcare.co.uk BOC Healthcare is the trading name of BOC Limited registered office, Forge, 43 Church Street West, Woking, Surrey GU21 6HT, England. Company number 337663 – English Register. Authorised and regulated by the Financial Conduct Authority, register number 715528. BOC is a company name used by Linde plc and its affiliates. The BOC logo and the BOC word are trademarks or registered trademarks of Linde plc or its affiliates. Copyright © 2013–2022. BOC Ltd.

About this document

Source: MHRA - Medicines and Healthcare products Regulatory Agency (products.mhra.gov.uk) · Marketing authorisation: PL 00735/5006

MHRA data as of 13 October 2026

Found a mistake? Tell us on the contact page.

The information on this site does not replace the advice of a doctor or pharmacist.

Facts about Medical Carbon Dioxide

Prescription needed? No, but it is sold only in pharmacies (P)
Active substance Carbon dioxide
Strength 1 ml/ml
Pharmaceutical form Inhalation gas
How is it taken Inhalation
Pack sizes 450 litre, 1800 litre, 3600 litre
Is it available? Listed as available (NHS Dictionary of Medicines and Devices – not a record of current supplies)
Storage Carbon Dioxide cylinders should be:
stored under cover, preferably inside, kept dry and clean, and not subjected to extremes of heat or cold and away from stocks of combustible material.
stored separately from industrial and other non-medical cylinders.
stored to maintain separation between full and empty cylinders.
used in strict rotation so that cylinders with the earliest filling date are used first.
stored separately from other medical cylinders within the store
Warning notices prohibiting smoking and naked lights must be posted clearly in the cylinder storage area and the Emergency Services should be advised of the location of the cylinder store.
Care is needed when handling and using Medical Carbon Dioxide cylinders.
Drug group (ATC) Medical Gases
  1. V Various drug classes
    1. V03 All other therapeutic products
      1. V03A All other therapeutic products
        1. V03AN Medical gases
          1. V03AN02 carbon dioxide
Marketing authorisation PL 00735/5006 (first authorised 1 September 1972)
Marketing authorisation holder BOC Ltd
Codes GTIN 5015573201032, 5015573201056, 5015573201254, 5015573201261 · BNF 19150000

Sources: the MHRA product information (products.mhra.gov.uk) and the NHS Dictionary of Medicines and Devices (dm+d), release 10.1.0 of 12 October 2026, NHS Business Services Authority. Contains public sector information licensed under the Open Government Licence v3.0.