Patient leaflet - Jascayd 18 mg film-coated tablets
1. What Jascayd is and what it is used for
What Jascayd is
Jascayd contains the active substance nerandomilast.
It is a medicine called a phosphodiesterase 4B inhibitor, which helps to regulate the activity of your immune system and to reduce tissue scarring.
What Jascayd is used for
Jascayd is used:
to treat adults with a lung disease called Idiopathic Pulmonary
Fibrosis (IPF).
to treat adults with a lung disease called Progressive Pulmonary
fibrosis (PPF).
IPF and PPF are conditions in which the tissue in your lungs becomes thickened, stiff and scarred over time. As a result, scarring reduces the ability to transfer oxygen from the lungs into the bloodstream and it becomes difficult to breathe deeply. Jascayd helps to reduce further scarring and stiffening of the lungs and helps you to breathe better.
2. What you need to know before you take Jascayd
Do not take Jascayd
if you are allergic to nerandomilast or any of the other ingredients
of this medicine (listed in section 6).
Children
Do not give this medicine to children. It is not known if this medicine is safe and effective in children.
Other medicines and Jascayd
Jascayd may affect the way other medicines work, and other medicines may affect how Jascayd works.
Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines. This includes medicines obtained without a prescription and herbal medicines.
This is especially important if you are taking pirfenidone (another medicine to treat IPF), as it can reduce how well Jascayd works.
Tell your doctor if you take any of the medicines listed below. Your doctor may reduce your dose of Jascayd if you take any of these.
- Clarithromycin: an antibiotic medicine to treat bacterial infections
- Itraconazole: a medicine to treat fungal infections
Ritonavir: a medicine to treat HIV infections
Additionally, tell your doctor or pharmacist before taking Jascayd if you are taking any of the following medicines as it is expected that they may reduce how well Jascayd works:
Carbamazepine: a medicine to treat epilepsy and certain nerve
pain
St. John's wort: a herbal medicine used to help with mild
depression, symptoms of menopause, and certain mood-related conditions such as anxiety
Rifampicin: an antibiotic medicine to treat tuberculosis and other
bacterial infections
- Phenytoin: a medicine to treat epilepsy
- Bosentan: a medicine to treat pulmonary arterial hypertension
- Metamizole: a medicine to relieve pain and reduce fever
Pregnancy and breast-feeding
If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.
This medicine may cause loss of your pregnancy (miscarriage). You should use effective contraception during treatment with Jascayd. If you become pregnant while being treated with this medicine, tell your doctor straight away. You and your doctor will decide if the benefit of having the medicine is greater than the risk to your baby.
It is not known if this medicine passes into your breastmilk. Do not breastfeed during treatment with Jascayd.
Driving and using machines
This medicine is not expected to affect your ability to drive and use machines.
Jascayd contains lactose
If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicinal product.
Jascayd contains sodium
This medicine contains less than 1 mmol sodium (23 mg) per tablet, that is to say essentially ‘sodium-free’.
3. How to take Jascayd
Always take this medicine exactly as your doctor or pharmacist has told you. Check with your doctor or pharmacist if you are not sure.
Your doctor will tell you how much Jascayd to take and when to take it.
The recommended dose is 1 tablet of Jascayd 18 mg twice daily.
Take the tablets approximately 12 hours apart.
Your doctor may decide to reduce your dose of Jascayd to 9 mg twice daily depending on:
- How well you tolerate Jascayd or
- Any other medicines you are taking.
Taking this medicine
- Swallow the tablets whole with water.
You can take the tablet with or without food.
If you cannot swallow Jascayd tablets whole:
Place about 100 mL of non-carbonated, room temperature water
in a glass. Do not use any other liquids.
- Drop the tablet in water without crushing it.
Stir regularly for approximately 15 to 20 minutes until the tablet is
in very small pieces (the tablet will not completely dissolve).
- Drink the Jascayd and water mixture within 2 hours of mixing.
If you do not drink the mixture right away, stir the mixture again
before drinking.
Rinse the glass with about 100 mL of water and drink it. This
ensures you have taken the full dose.
If you take more Jascayd than you should
Contact your doctor or pharmacist immediately.
If you forget to take Jascayd
If you forget a dose, take your next dose at your regular time. Do not take the missed dose. Do not take more than 2 tablets of 18 mg Jascayd in 1 day.
If you stop taking Jascayd
You should continue taking Jascayd until your doctor tells you to stop. Do not stop taking Jascayd without talking to your doctor first.
If you have any further questions on the use of this medicine, ask your doctor or pharmacist.
4. Possible side effects
Like all medicines, this medicine can cause side effects, although not everybody gets them.
Talk to your doctor if you get any side effects.
Very common side effects (may affect more than 1 in 10 people):
- Diarrhoea
- Weight loss
Common side effects (may affect up to 1 in 10 people):
- Nausea
- Decreased appetite
- Back pain
Reporting of side effects
If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. You can also report side effects directly (see details below). By reporting side effects you can help provide more information on the safety of this medicine.
Yellow Card Scheme
Website: www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store
5. How to store Jascayd
Keep this medicine out of the sight and reach of children.
Do not use this medicine after the expiry date which is stated on the blister or label and on the carton after EXP. The expiry date refers to the last day of that month.
Store in the original package in order to protect from light. This medicine does not require any special temperature storage conditions.
Do not throw away any medicines via wastewater. Ask your pharmacist how to throw away medicines you no longer use. These measures will help protect the environment.
6. Contents of the pack and other information
What Jascayd contains
Jascayd 9 mg tablets:
- The active substance is nerandomilast. Each tablet contains 9 mg nerandomilast.
The other ingredients are:
- Lactose monohydrate
- Microcrystalline cellulose
- Hydroxypropylcellulose
- Croscarmellose sodium
- Magnesium stearate
- Hypromellose 2910
- Talc
- Mannitol
- Macrogol 8000
- Iron oxide yellow (E172)
Jascayd 18 mg tablets
- The active substance is nerandomilast. Each tablet contains 18 mg nerandomilast.
The other ingredients are:
- Lactose monohydrate
- Microcrystalline cellulose
- Hydroxypropylcellulose
- Croscarmellose sodium
- Magnesium stearate
- Hypromellose 2910
Talc
- Mannitol
- Macrogol 8000
- Iron oxide red (E172)
- Iron oxide black (E172)
What Jascayd looks like and contents of the pack
Jascayd 9 mg film-coated tablets are light yellow, oval and biconvex. They have “F9” on one side and the Boehringer Ingelheim logo on the other side. The tablets are 9.5 mm long and 4.6 mm wide.
Jascayd 18 mg film-coated tablets are light red, oval and biconvex. They have “F18” on one side and the Boehringer Ingelheim logo on the other side. The tablets are 12 mm long and 5.9 mm wide.
Jascayd tablets are available in:
PVC/aluminium perforated unit dose blisters.
The pack sizes are 10 x 1, 30 x 1 or 60 x 1 film-coated tablets.
HDPE bottle with a child-resistant closure.
The pack sizes are 60 or 180 film-coated tablets.
Not all pack sizes may be marketed in your country.
Marketing Authorisation Holder
Boehringer Ingelheim International GmbH
Binger Strasse 173
55216 Ingelheim am Rhein
Germany
Manufacturer
Boehringer Ingelheim Pharma GmbH & Co. KG
Binger Strasse 173
55216 Ingelheim am Rhein
Germany
For any information about this medicine, please contact the local representative of the Marketing Authorisation Holder:
United Kingdom
Boehringer Ingelheim Ltd.
Tel: +44 1344 424 600
This leaflet was last revised in 05/2026.
Package leaflet: Information for the patient
Jascayd® 9 mg film-coated tablets Jascayd® 18 mg film-coated tablets nerandomilast
abcd
Jascayd® 9 mg film-coated tablets Jascayd® 18 mg film-coated tablets
nerandomilast
abcd
Jascayd® 9 mg film-coated tablets Jascayd® 18 mg film-coated tablets
nerandomilast
abcd
P060001-001 MASS D: 0,5 mm MASS E: 1,5 mm MASS G: 1,0 mm
| File information | ||||
| Issue date of TD: | ||||
Perigord No: 898281 P5
| Mandatory in | ||||
| TD | Printfile | |||
PPM SKU: P060001 24.08.2021 | Yes No | Yes Yes | ||
| PPM SKU version: 001 | No | Yes | ||
| No | Yes | |||
| Print colors: PAN BLACK | No | Yes | ||
| Mat. No. Pack. Site: P060001-001 | No | Yes | ||
| Additional Requirements of Packaging site | |
| Template name: PI_850x378_85x55 | Index: 2.0 |
Example:
| Only for BI-internal use, Template according to Drawing no.: SP-14-0053-001-B_Index_g |
In-process control code specification