Patient leaflet - Hyperiforce ST Johns Wort tablets
1. What the product is for
Hyperiforce is a traditional herbal medicinal product used to relieve the
symptoms of slightly low mood and mild anxiety. This is based on traditional use only.
Used to help with:
Feeling down or low
Feeling stressed and anxious
Suffering from depression?
This product is for symptoms of slightly low mood and mild anxiety. If you think you are suffering from depression and have thoughts of self-harm, suicide or any other symptoms of depression you should see your doctor. Other symptoms of depression can include feeling hopeless and helpless, finding it hard to concentrate, loss of interest in your daily activities, tiredness, changes to your appetite or weight and changes in your sleeping patterns.
i Information
Patient Information Leaflet Do's and Don'ts for taking this product
2. Before you take this product
Do not take this product
If you are under 18 years of age.
If you are allergic to any of the ingredients in this product (see section 6 Further Information).
If you are pregnant or breast-feeding.
If you are suffering from depression (see section 1 What the product is for).
If your skin is exceptionally sensitive to sunlight
(photosensitive).
If you are having light treatment (phototherapy) for any condition.
Taking this product with other medicines
St John's Wort can affect the way some medicines work and reduce their effectiveness. Medicines that can be affected by St John's Wort include prescription medicines, and those that you may have bought without a prescription.
It is therefore important that you do not take St John's Wort if you are using any of the medicines listed in the following table.
| All medicines for anxiety or depression | This includes amitriptyline, clomipramine, moclobemide, citalopram, escitalopram, fluoxetine, fluvoxamine, paroxetine, sertraline, duloxetine, venlafaxine. It also includes benzodiazepines e.g. diazepam, alprazolam. | A mood-regulating medicine | Lithium |
| A thyroid hormone | Thyroxine | ||
| An antihistamine | Fexofenadine | ||
| All hormonal contraceptives | This includes oral contraceptives (the Pill), emergency contraception (the morning-after pill) and other forms of contraception such as hormonal implants, creams, patches, intra-uterine devices with hormones. If you are unsure as to whether your contraception contains hormones please see your pharmacist. | ||
All hormone replacement therapy (HRT) treatments | These come in a number of forms including tablets, patches, gels and vaginal rings. | ||
| Prostate medicine | Finasteride | ||
| All medicines for epilepsy | Carbamazepine, phenobarbitone, phenytoin, primidone, sodium valproate | ||
All immunosuppressant medicines | Ciclosporin, sirolimus, tacrolimus | ||
| All medicines for HIV infections | Amprenavir, atazanavir, darunavir, fosamprenavir, indinavir, lopinavir, nelfinavir, ritonavir, saquinavir, tipranavir (HIV protease inhibitors) Delavirdine, efavirenz, nevirapine (HIV non-nucleoside reverse transcriptase inhibitors) | ||
All blood thinning medicines (anticoagulants) | Acenocoumarol, warfarin | ||
| Some medicines for heart conditions | Amiodarone, digoxin, ivabradine | ||
| Some medicines for high blood pressure | Amlodipine, felodipine, nifedipine, verapamil | ||
| Some medicines for cholesterol | Atorvastatin, simvastatin | ||
| Some medicines for migraines | Almotriptan, eletriptan, frovatriptan, nartriptan, rizatriptan, sumatriptan, zolmitriptan | ||
| Some medicines for cancer | Dastinib, erlotinib, etoposide, everolimus, imatinib, irinotecan, mirotane, sorafenib, sunitinib | ||
| A medicine for pain relief or opioid dependency | Methadone |
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St John’s Wort may also affect the following medicines. Do not take this product with these medicines unless a doctor has said it is safe to do so:
Fentanyl, propofol, sevoflurane and midazolam (anaesthetics/pre-operative medicines) Tramadol (a pain killer)
Erythromycin, clarithromycin and telithromycin (antibiotics)
Itraconazole and voriconazole (antifungals) Artemether and lumefantrine (used to treat malaria)
Rasagiline (used to treat Parkinson’s) Aripiprazole (an antipsychotic medicine) Buspirone (an anxiolytic)
Aprepitant (used to treat post-operative vomiting)
Butobarbital and phenobarbital (barbiturates) Methyl phenidate (a central nervous system (CNS) stimulant)
Exemestane (a hormone antagonist) Eplerenone (a diuretic)
Lansoprazole and omeprazole (proton pump inhibitors)
Theophylline (a bronchodilator)
Gliclazide (a medicine for diabetes)
If you are unsure if this product is suitable for you then please contact your pharmacist or our Helpline on 0845 608 5858.
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3. How to take this product
Adults and the elderly: 1 tablet three times daily.
Don't take more than the recommended dose.
Not for use in children or those under 18 years of age.
Take special care with this product
Avoid prolonged sunbathing or the use of sunbeds or solariums whilst taking this product. St John's wort may cause your skin to be much more sensitive to sunlight. Remember to tell your doctor you are taking this product if you have to have an operation. This product should be stopped 10 days before an operation.
Driving and using machines
This product may make you feel dizzy or tired. If this happens to you, do not drive or use machines.
If you take too much
If you take too much and feel ill, talk to your doctor.
If you forget to take this product
Don't worry about the missed dose. Take the next tablet as usual.
If you feel this product isn't working
See your doctor:
If you do not feel an
improvement within six weeks, or if you feel worse. If your symptoms begin to interfere significantly with how you live your
everyday life or if you have thoughts of self-harm or suicide.
Using Side effects i Information
4. Possible side effects
Like all medicines, this product can cause side effects, although not everybody gets them.
The following side effects can occur when using this product.
The frequency of these effects occurring is not known.
Digestive symptoms such as
Indigestion
Loss of appetite
Feeling sick (nausea)
Diarrhoea
Constipation
These are often short-lived and should go away by themselves. However if they are troubling you, talk to your doctor or pharmacist.
Allergic skin reactions
Rash
Red, itchy spots (urticaria/ hives)
Itching (pruritis)
Stop taking the product if these occur.
Other side effects
Fatigue
Restlessness
Sunburn-like reactions on skin exposed to strong sunlight or strong ultra-violet (UV) radiation e.g. solarium, particularly in people with fair skin
Headaches
Nerve pain or tingling (neuropathy)
Anxiety
Dizziness
Mania
If you are concerned about any side effect listed above or any other side effect occurs, please talk to your doctor or pharmacist.
Reporting of side effects
If you get any side effects, talk to your doctor,
pharmacist or nurse. This includes any possible side effects not listed in this leaflet.
You can also report side effects directly via the Yellow Card Scheme at www.mhra.gov.uk/ yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store.
By reporting side effects you can help provide more information on the safety of this medicine.
5. How to store this product
Keep out of the sight and reach of children.
Do not use this product after the expiry date on the packaging. The expiry date refers to the last day of that month.
Use within 8 months of opening.
This product does not require any special storage conditions.
Do not use this product if you notice a change in appearance. The tablets should be oval and brown green in colour.
6. Further
Information
What this product contains
One tablet contains 66 mg of extract (as dry extract) from fresh St John's wort (Hypericum perforatum L.) flowering herb (equivalent to 170-305 mg of dried St John's wort flowering herb). Extraction solvent: Ethanol 68% V/V.
The other ingredients used for the tablet are microcrystalline cellulose, croscarmellose sodium, colloidal anhydrous silica and glycerol distearate.
What this product looks like and the contents of the pack
Hyperiforce tablets are oval and brown green in colour. Hyperiforce is available in packs of 60 or 120 tablets. Not all pack sizes may be marketed.
Traditional Herbal Registration Holder and Manufacturer Traditional Herbal
Registration Holder and Batch Release:
A.Vogel Ltd,
2 Brewster Place,
Irvine, Ayrshire, UK
KA11 5DD
Manufacturer:
A.Vogel AG, CH-9325,
Roggwil, Switzerland
THR No. 13668/0014
This leaflet was revised on 04/2026.
What is St John's wort?
St. John's wort, also known as Hypericum perforatum, is a plant which has been used as a herbal medicine for many years. The flowers and leaves found at the top of the plant are used to make this product.
You should also know
A.Vogel runs a helpline by phone and email which can provide you with further information.
Email: enquiries@avogel.co.uk Phone: 0845 608 5858
You can get a larger print or audio version of this leaflet.
Call this number: 0845 608 5858.
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Certification Mark
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