Hiprex 1g tablets – patient leaflet, side effects, dosage

1. What Hiprex is and what it is used for

Hiprex contains the active substance methenamine hippurate and belongs to a group of medicines called anti-bacterials. These work by killing many different types of bacteria which cause infections.

Hiprex is used to treat infections of the urinary tract and stop them from coming back. The urinary tract is a collective name for the parts of the body that produce, store and transport urine. These include the kidney, bladder and tubes called the ureter and urethra. It is also used to avoid urinary tract infections in patients with catheters from their bladders (a tube that helps with incontinence) and in people undergoing certain medical procedures.

2. What you need to know before you take Hiprex

Do not use Hiprex if:

• You are allergic to methenamine hippurate or any of the other ingredients of this medicine (listed in section 6)
• You are taking antibiotic medicines called sulphonamides. These can damage your kidneys when taken at the same time as Hiprex
• You are severely dehydrated
• You have serious problems with your kidneys
• You have problems with your liver
• You have gout
• You have a condition called metabolic acidosis (a chemical imbalance in the blood).

If any of the above applies to you, talk to your doctor or pharmacist.

Warnings and precautions

Talk to your doctor or pharmacist before taking Hiprex if:

• You have any kinds of problems with your kidneys.

Tell your doctor if you are taking any of the following medicines:

• Medicines to make your urine less acidic such as potassium citrate and acetazolamide. These can stop Hiprex working properly.
• Any other medicines, including medicines obtained without a prescription.

Pregnancy, breast-feeding and fertility

If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.

3. How to take Hiprex

Always take Hiprex exactly as your doctor or pharmacist has told you. You should check with your doctor or pharmacist if you are not sure.

Important:

Your doctor will choose the dose that is right for you. Your dose will be shown clearly on the label that your pharmacist puts on your medicine. If it does not, or you are not sure, ask your doctor or pharmacist. Adults

The recommended dose is one tablet twice a day.

If you have a catheter your doctor may increase your dose to one tablet three times a day. Use in children

Not for children aged under 6.

Children aged 6 – 12 years the recommended dose is half a tablet (500mg) twice a day.

Method of administration

The tablets can be broken in half. If you find it particularly difficult to swallow them, the tablets may be crushed and taken with a drink of milk or fruit juice.

If you take more Hiprex than you should

If you accidentally take more Hiprex than you should, you might be sick or see blood in your urine. Drink plenty of water and immediately go to the nearest hospital casualty department or your doctor. Your doctor may give you another medicine to stop you being sick.

If you forget to take Hiprex

Do not take a double dose to make up for a missed dose. Simply take your next dose as planned. If you stop taking Hiprex

Your doctor will tell you how long to take your medicine for. Do not stop taking Hiprex without first talking to your doctor. If you have further questions on the use of this medicine, ask your doctor or pharmacist.

4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them. You may experience the following:

Uncommon: may affect up to 1 in 100 people

• Rashes
• Itching
• Stomach irritation
• Bladder irritation usually seen as a burning sensation and pain on urinating
• Nausea
• Vomiting

Not known (cannot be estimated from the available data)

• Diarrhoea, abdominal pain

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Reporting of side effects

If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Yellow Card Scheme at: www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store.

By reporting side effects you can help provide more information on the safety of this medicine.

5. How to store Hiprex

Keep this medicine out of the sight and reach of children.

Do not use Hiprex after the expiry date which is stated on the bottle. The expiry date refers to the last day of that month.

Store Hiprex below 30 °C, with the bottle lid tightly closed in its original carton.

Medicines should not be disposed of via wastewater or household waste. Return any medicine you no longer need to your pharmacist.

6. Contents of the pack and other information

What Hiprex contains

The active substance is methenamine hippurate. Each tablet contains 1 gram.

The other ingredients are magnesium stearate (E572), povidone and colloidal anhydrous silica. What Hiprex looks like

A white to creamy-white oblong shaped tablet coded HX with break line on one face and break line on the other face. Hiprex comes in a glass bottle which contains 60 tablets.

Marketing Authorisation Holder:

Viatris Products Limited,

Station Close,

Potters Bar,

EN6 1TL,

United Kingdom.

Manufacturer:

Fine Foods & Pharmaceuticals N.T.M. S.p.A.

Via Grignano, 43,

24041 Brembate (BG),

Italy

Mylan Hungary Kft.

Mylan utca 1,

Komarom 2900,

Hungary

This leaflet was last revised in October 2025.

If this leaflet is difficult to see or read and you would like it in a different format, please contact Viatris Products Limited, Station Close, Potters Bar, EN6 1TL, United Kingdom.

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5002122_01 Hiprex is a trademark of MEDA AB.

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Date: Time:

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