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ERYTHROMYCIN 250 MG TABLETS, RETCIN - Patient leaflet, side effects, dosage

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Sources: Original (products.mhra.gov.uk)

Patient leaflet - ERYTHROMYCIN 250 MG TABLETS, RETCIN

PATIENT INFORMATION LEAFLET

RETCIN (Erythromycin)

PLEASE READ THIS LEAFLET CAREFULLY BEFORE YOU START TAKING THIS MEDICINE

KEEP THIS LEAFLET UNTIL YOU HAVE FINISHED ALL THE PRESCRIBED COURSE OF RETCIN.
IF YOU HAVE ANY QUESTIONS CONCERNING YOUR MEDICINE ASK YOUR DOCTOR OR PHARMACIST FOR MORE INFORMATION.

What is in your medicine?

The name of this medicine is RETCIN. It contains the active ingredient Erythromycin Ph.Eur. 274 mg.

Each Retcin tablet also contains the inactive ingredients: lactose, maize starch, potato starch, sodium starch glycollate, magnesium stearate, cellacephate, diethylphthalate, colour Ponceau 4R (E124), carnauba wax, beeswax, acetone, methanol, dichloromethane.

Retcin is a round, red, film-coated tablet of 250 mg strength, available in containers of 28, 30, 50, 56, 60, 84, 100, 250, 500 and 1000 tablets.

The name and address of the Product Licence holder of Retcin tablets is Chelonia Heathcare Limited, 11 Boumpoulinas, 1060 Nicosia, Cyprus.

The name and address of the manufacturer of Retcin tablets is Meridian Healthcare (UK) Ltd., Rich Industrial Estate, Chatfield Road, off York Road, Battersea, London SW11 3SE.

How does Retcin work?

Retcin is an antibiotic that acts on bacteria sensitive to Erythromycin.

Why have you been prescribed Retcin?

Retcin is used for the prevention and treatment of infections caused by Erythromycin sensitive organisms. It is used in the treatment of:

  • Chest infections
  • Skin and soft tissue infections
  • Bone infections
  • Mouth and dental infections
  • Stomach infections
  • Eye infections
  • Sexually transmitted diseases
  • Legionnaire’s Di­sease

Before taking Retcin

Before taking this medicine, tell your doctor if you have ever had any unusual or allergic reactions to Erythromycin or any of the other ingredients of Retcin, or any other antibiotics. This product contains lactose and is unsuitable for people with lactase insufficiency, galactosaemia or glucose/galactose malabsorption syndrome. Retcin also contains the colour Ponceau 4R (E124) which may cause allergic-type reactions including asthma. Allergy is more common in those people who are allergic to aspirin.

Also tell your doctor or pharmacist if you are allergic to any other substances such as foods, preservatives or dyes.

It is important that you tell your doctor if you are pregnant, breast-feeding or likely to become pregnant.

The presence of other medical problems may affect the use of this medicine. Tell your doctor if you have:

  • liver problems for which you have or are receiving treatment
  • kidney problems
  • heart problems or a condition known as porphyria

Use in pregnancy and while breast-feeding Erythromycin has not been shown to be harmful during pregnancy.

Ask your doctor for advice before breast-feeding whilst taking these tablets as erythromycin can pass into breast milk.

Can you drive or operate machinery when taking Retcin?

Retcin will not affect your ability to drive or operate machinery.

Can you take Retcin with other medicines?

There are some medicines that can interfere with Retcin. It is very important to tell your doctor or pharmacist about all the medicines that you are taking, whether or not any medicines were prescribed by your doctor or bought without a prescription from the pharmacy or elsewhere. Your doctor will be able to identify medicines you should not take with Retcin.

Especially make sure to tell your doctor if you have or are taking a medicine known as Terfenadine (which you may have purchased over-the-counter), or Astemizole both used for hay fever and relief of allergies. They should not be taken together with Retcin, they could damage your heart.

Cisapride – for stomach disorders and Pimozide and Sertindole – for psychiatric disorders all cause irregular heart beat when taken with Retcin.

Ergotamine and di-hydroergotamine used for attacks of migraine which can lead to toxic reactions when taken with Erthromycin.

Retcin may increase the blood thinning effect of coumarins.

Other medicines which interfere with Retcin include:

Simvastatin and Atorvastatin used to reduce cholesterol levels. Digoxin and Disopyramide used to treat heart conditions, Warfarin used to thin the blood, Carbamazepine used to treat epilepsy and to prevent manic-depressive illness, Phenytoin used to treat epilepsy, Eletriptan – for migraine, Theophylline used to treat obstruction of airways including severe asthma, Ciclosporin used to treat psoriasis, Mizolastine for allergic or itchy skin rash, Methylpredniso­lone to treat inflammatory conditions, Bromocriptine and Cabergoline used in the treatment of Parkinson’s Di­sease, Triazolam an anti-fungal medicine, Ritonavir to treat HIV, the sedatives Midazolam and Zopiclone , Clozapine for mental disorders, Reboxetine for depressive illness, Tolterodine for urinary problems, Corticosteroids , Sirolimus and Tacrolimus used following organ transplants, the antibacterial Rifabutin , Lercanidipine for high blood pressure and Vinblastine to stop the growth of certain cells.

Retcin can also affect the blood concentration of certain other medicines you may be taking. Your doctor will have more information.

When and how to take Retcin tablets

Take this medicine by mouth and only in the doses prescribed by your doctor. Do not take more of it, and do not take it more often or for a longer time than your doctor ordered.

Usual dosages stated below:

The medicine is to be taken by mouth. Do not crush or bite, but swallow whole.

Adults and children over 8 years : 1–2 g (four to eight tablets) daily in divided doses for mild to moderate infection. This dosage may be increased to 4 g (sixteen tablets) daily in divided doses. Tablets should be taken before or with meals.

Elderly : as for adults.

Length of medication with regard to treatment of particular infections :

Upper respiratory tract infections:

  • 5 to 10 days

Sources: Original (products.mhra.gov.uk)

Frequently Asked Questions

What is Erythromycin 250 mg used for?

Erythromycin 250 mg tablets are used to treat various bacterial infections, including respiratory tract infections, skin infections, and some sexually transmitted diseases.

How should I take Erythromycin 250 mg tablets?

Take Erythromycin 250 mg tablets by mouth, usually every 6 hours or as directed by your doctor. It's best to take them on an empty stomach for better absorption.

Can I take Erythromycin with food?

While it's best to take Erythromycin on an empty stomach, if it upsets your stomach, you can take it with food. However, this may reduce its absorption effectiveness.

What are the common side effects of Erythromycin?

Common side effects include nausea, vomiting, diarrhea, abdominal pain, and loss of appetite. Contact your doctor if these effects persist or worsen.

Is Erythromycin safe for pregnant women?

Erythromycin is generally considered safe for use during pregnancy. However, always consult your healthcare provider before taking any medication while pregnant.

Can I drink alcohol while taking Erythromycin?

It's advisable to limit alcohol consumption while on Erythromycin as it may increase side effects like stomach upset and dizziness.

What should I do if I miss a dose of Erythromycin?

If you miss a dose of Erythromycin, take it as soon as you remember. If it's close to the time of your next dose, skip the missed dose and resume your regular schedule. Never double up on doses.

Are there any serious side effects of Erythromycin to watch out for?

Serious side effects can include allergic reactions (rash, itching, swelling), severe gastrointestinal issues, and liver problems. Seek immediate medical attention if you experience any severe reactions.

Can children take Erythromycin 250 mg tablets?

Yes, but the dosage may differ based on the child's weight and specific infection type. Always follow your pediatrician's guidance regarding medication for children.

Will Erythromycin interact with other medications I’m taking?

Yes, Erythromycin can interact with various medications like blood thinners and certain cholesterol-lowering drugs. Inform your doctor about all medications and supplements you are taking.

How long does it take for Erythromycin to work?

You may start to feel better within a few days. However, complete resolution of symptoms may take longer depending on the infection type. Always complete the prescribed course even if you feel better.

Can I stop taking Erythromycin if I feel better before finishing my prescription?

No, do not stop taking Erythromycin without consulting your doctor even if you feel better. Stopping early can lead to reinfection or resistance.

Is it normal to experience diarrhea while on Erythromycin?

Mild diarrhea is a common side effect of antibiotics like Erythromycin. However, if diarrhea is severe or contains blood or mucus, contact your healthcare provider immediately.

What should I do if I have an allergic reaction to Erythromycin?

If you experience symptoms of an allergic reaction such as rash, itching, or difficulty breathing after taking Erythromycin, seek emergency medical help right away.

Can I take over-the-counter pain relievers while on Erythromycin?

Yes, most over-the-counter pain relievers like acetaminophen can be taken with Erythromycin. Always consult your doctor or pharmacist before combining medications.

Does Erythromycin affect birth control pills?

Erythromycin does not typically reduce the effectiveness of hormonal birth control methods; however, it's always good practice to discuss potential interactions with your healthcare provider.

What should I tell my doctor before starting Erythromycin treatment?

Inform your doctor about any allergies you have, medical conditions (especially liver issues), and all medications you are currently taking before starting treatment with Erythromycin.

Where should I store my Erythromycin tablets?

Store Erythromycin tablets at room temperature away from moisture and heat. Keep them out of reach of children and pets.

Can I use expired Erythromycin tablets?

No, do not use expired medications. Dispose of them properly and consult your pharmacist for guidance on safe disposal methods.