Patient leaflet - BIMATOPROST 0.3 MG / ML EYE DROPS SOLUTION
Bimatoprost 0.3 mg/ml, eye drops, solution
Bimatoprost
Read all of this leaflet carefully before you start using this medicine because it contains important information for you.
- Keep this leaflet. You may need to read it again.
- If you have further questions, ask your doctor or pharmacist.
- This medicine has been prescribed for you only. Do not pass it on to others. It may harm them, even if their signs of illness are the same as yours.
- If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. See section 4.
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1. What Bimatoprost is and what it is used for
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2. What you need to know before you use Bimatoprost
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3. How to use Bimatoprost
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4. Possible side effects
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5. How to store Bimatoprost
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6. Contents of the pack and other information
1. what bimatoprost is and what it is used for
Bimatoprost is an antiglaucoma preparation. It belongs to a group of medicines called prostamides.
Bimatoprost is used to reduce high pressure in the eye. This medicine may be used on its own or with other drops called beta-blockers which also reduce pressure.
Your eye contains a clear, watery liquid that feeds the inside of the eye. Liquid is constantly being drained out of the eye and new liquid is made to replace this. If the liquid cannot drain out quickly enough, the pressure inside the eye builds up. This medicine works by increasing the amount of liquid that is drained. This reduces the pressure inside the eye. If the high pressure is not reduced, it could lead to a disease called glaucoma and eventually damage your sight.
2. what you need to know before you use bimatoprostdo not use bimatoprost :- if you are allergic to bimatoprost or any of the other ingredients of this medicine (listed in section 6).
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– if you have had to stop using eye drops in the past because of a side effect of the preservative benzalkonium chloride.
Warnings and precautions:
Talk to your doctor or pharmacist before you use Bimatoprost:
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– Talk to your doctor, if:
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– You have any breathing problems
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– You have liver or kidney problems
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– You have had a cataract surgery in the past
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– You have dry eye
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– You have or have had any problems with your cornea (front transparent part of the eye)
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– You wear contact lenses (see section 2 “Bimatoprost contains benzalkonium chloride”)
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– You have or have had low blood pressure or low heart rate
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– You have had a viral infection or inflammation of the eye
Bimatoprost may cause your eyelashes to darken and grow, and cause the skin around the eyelid to darken too. The colour of your iris may also go darker over time. These changes may be permanent. The change may be more noticeable if you are only treating one eye.
Children and adolescents
Bimatoprost has not been tested in children under the age of 18 and therefore Bimatoprost should not be used by patients under 18 years.
Other medicines and Bimatoprost
Tell your doctor or pharmacist if you are taking, or have recently taken, or might take any other medicines.
Pregnancy and breast-feeding
If you are pregnant or breast-feeding, think you might be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking any medicine.
Bimatoprost may pass into breast milk so you should not breast-feed while you are taking Bimatoprost.
Driving and using machines
Your sight may become blurred for a short time just after using Bimatoprost. You should not drive or use machines until your sight is clear again.
Bimatoprost contains benzalkonium chloride
Do not use the drops when you are wearing your lenses. Wait 15 minutes after using the drops before you put your lenses back in. A preservative in Bimatoprost called benzalkonium chloride may cause eye irritation and can discolour soft contact lenses.
Bimatoprost contains Disodium hydrogen phosphate heptahydrate
This medicine contains up to 0.05 mg phosphates in each drop which is equivalent to 0.95 mg/ml.
If you suffer from severe damage to the clear layer at the front of the eye (the cornea), phosphates may cause in very rare cases cloudy patches on the cornea due to calcium build-up during treatment.
3. how to use bimatoprost
Always use this medicine exactly as your doctor or pharmacist has told you. Check with your doctor or pharmacist if you are not sure.
Bimatoprost should only be applied to the eye. The recommended dose is one drop of Bimatoprost in the evening, once daily in each eye that needs treatment.
If you use Bimatoprost with another eye medicine, wait at least five minutes between using Bimatoprost and the other eye medicine.
Do not use more than once a day as the effectiveness of treatment may be reduced.
Instructions for use:
You must not use the bottle if the tamper-proof seal on the bottle neck is broken before you first use it.
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1. Wash your hands. Tilt your head back and look at the ceiling.
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2. Gently pull down the lower eyelid until there is a small pocket.
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3. Turn the bottle upside down and squeeze it to release one drop into each eye that needs treatment.
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4. Let go of the lower lid, and close your eye for 30 seconds.
Wipe off any excess that runs down the cheek.
If a drop misses your eye, try again.
To help prevent infections and avoid eye injury, do not let the tip of the bottle touch your eye or anything else. Put the cap back on and close the bottle straight after you have used it.
If you use more Bimatoprost than you should
If you use more Bimatoprost than you should, it is unlikely to cause you any serious harm. Put your next dose in at the usual time. If you are worried, talk to your doctor or pharmacist.
If you forget to use Bimatoprost
If you forget to use Bimatoprost, use a single drop as soon as you remember, and then go back to your regular routine. Do not take a double dose to make up for a forgotten dose.
If you stop using Bimatoprost
Bimatoprost should be used every day to work properly. If you stop using Bimatoprost the pressure inside your eye may go up, therefore talk to your doctor before stopping this treatment.
If you have any further questions on the use of this medicine, ask your doctor or pharmacist.
4. possible side effects
Like all medicines, this medicine can cause side effects, although not everybody gets them.
Very common (may affect more than 1 in every 10 users)
Affecting the eye
- Longer eyelashes (up to 45% of people)
- Slight redness (up to 44% of people)
- Itchiness (up to 14% of people)
Common (may affect up to 1 in 10 users)
Affecting the eye
- An allergic reaction in the eye
- Tired eyes
- Sensitivity to light
- Darker skin colour around the eye
- Darker eyelashes
- Pain
- A feeling that something is in your eye
- Sticky eyes
- Darker iris colour
- Difficulty in seeing clearly
- Irritation
- Burning
- Inflamed, red and itchy eyelids
- Tears
- Dryness
- Worsening of vision
- Blurred vision
- Swelling of the see-through layer which covers the surface of the eye
- Small breaks in the surface of the eye, with or without inflammation
Affecting the body
- Headaches
- An increase in blood-test results that show how your liver is working
- Increased blood pressure
Uncommon (may affect less than 1 in 100 people)
Affecting the eye
- Cystoid macular oedema (swelling of the retina within the eye leading to worsening vision)
- Inflammation within the eye
- Retinal bleeding
- Swollen eyelids
- Eyelid twitching
- Eyelid shrinking, moving away from surface of the eye
- Skin redness around the eye
Affecting the body
- Nausea
- Dizziness
- Weakness
- Hair growth around the eye
Not known (frequency cannot be estimated from the available data)
Affecting the eye
- Eyes appear sunken
- Ocular discomfort
Affecting the body
- Asthma
- Worsening of asthma
- Worsening of the lung disease called chronic obstructive pulmonary disease (COPD)
- Shortness of breath
- Symptoms of allergic reaction (swelling, redness of the eye and rash of the skin)
- Skin discoloration (periocular)
Other side effects reported with eye drops containing phosphates
In very rare cases, some patients with severe damage to the clear layer at the front of the eye (the cornea) have developed cloudy patches on the cornea due to calcium build-up during treatment.
Reporting side effects
If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. You can also report side effects directly the Yellow Card Scheme, Website: or search for ‘MHRA Yellow Card’ in the Google Play or Apple App Store. By reporting side effects you can help provide more information on the safety of this medicine.
5. how to store bimatoprost
Keep this medicine out of the sight and reach of children.
Do not use this medicine after the expiry date which is stated on the bottle label and the carton after EXP. The expiry date refers to the last day of that month.
This medicine does not require any special storage conditions.
You must throw away the bottle, at the latest, four weeks after you first opened it, even if there are still some drops left. This will prevent infections. To help you remember, write down the date you opened it in the space on the box.
Do not throw away any medicines via wastewater or household waste. Ask your pharmacist how to throw away medicines you no longer use. These measures will help protect the environment.
6. contents of the pack and other informationwhat bimatoprost contains- the active substance is bimatoprost. one ml of solution contains 0.3 mg bimatoprost.
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– The other ingredients are benzalkonium chloride (preservative), citric acid monohydrate, disodium hydrogen phosphate heptahydrate, sodium chloride and water for injection. Small amounts of hydrochloric acid or sodium hydroxide may be added to keep the level of acid (pH levels) normal.
What Bimatoprost looks like and contents of the pack
Bimatoprost is a colourless clear eye drop solution in a pack containing either 1 plastic bottle or 3 plastic bottles each with a screw cap. Each bottle is approximately half full and contains 3 millilitres of solution. This is enough for 4 weeks’ usage. Not all pack sizes may be marketed.
Marketing Authorisation Holder and Manufacturer
Marketing Authorisation Holder
Neon Healthcare Ltd.
8 The Chase, John Tate Road, Hertford, SG13 7NN, United Kingdom
Manufacturer
Rafarm S.A.
Thesi Pousi-Xatzi Agiou Louka, Paiania-Attiki, 19002, P.O. Box 37, Greece
This leaflet was last revised in 07/2021
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