Patient leaflet - Aspirin 300 mg tablets BP
1. WHAT ASPIRIN 300 mg TABLETS ARE AND WHAT THEY ARE USED FOR
Aspirin 300mg Tablets contain the active ingredient called Aspirin. It belongs to a group of medications called salicylates. It is used for the relief of:
- Mild to moderate pain including headache
- Symptomatic relief of rheumatic pains (pain in joints), strains, sprains, joint swelling and stiffness
- Symptomatic relief of sciatica (pain down into the leg, which travels below the knee, and may involve the foot) & general lower back pain
- Fibrositis (muscle pain, stiffness and easy tiredness)
- Neuralgia (pain in the nerves)
- Painful conditions such as toothache
- Period pains
- Sore throat.
2. WHAT YOU NEED TO KNOW BEFORE YOU TAKE ASPIRIN 300 mg TABLETS
Do not take Aspirin Tablets if you:
are allergic (hypersensitive) to Aspirin or any of the other ingredients of Aspirin
Tablets. See section 6.
are in the last three months of your pregnancy, you must not use higher doses than
100 mg per day (see section “Pregnancy, breast-feeding and fertility”)
- have or ever had a peptic ulcer (ulcer in your stomach or duodenum)
- have haemophilia (where you bleed for longer than normal time) or other clotting disorder
- have gout.
Warnings and Precautions
Talk to your doctor or pharmacist or nurse before taking Aspirin 300mg.
Take special care with Aspirin Tablets if you have:
- asthma, or suffer from allergies
- heart, liver or kidney problems
- a history of stomach and intestinal problems
- or ever had stomach or intestinal bleeding problems
- or ever had holes in the intestine
- lost lots of body fluids (dehydration)
- When taking acetylsalicylic acid, serious allergic reactions which may include chest pain and even heart attack (Kounis syndrome) have been reported (see section 4). Seek medical care immediately when you notice chest pain with allergic reactions (such as skin rashes, shortness of breath).
Children and adolscents
There is a possible association between Aspirin and Reye’s syndrome (a serious condition in which fat builds up on the brain, liver, and other body organs) when given to children. For this reason, Aspirin should not be given to children aged under 16 years, unless on the advice of a doctor.
Other medicines and Aspirin 300 mg
Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines.
If you see another doctor, attend hospital for surgery involving an anaesthetic, let them know what medicines you are taking.
Examples of medicines that can affect Aspirin Tablets are:
- ACE inhibitors to treat high blood pressure
- painkillers like NSAIDs (non-steroidal anti-inflammatory drugs)
- Heparin, Phenindione, Coumarins - anticoagulants to stop blood clotting
- indigestion remedies
- Corticosteroids
- Methotrexate to treat cancer and auto immune diseases
- Spironolactone - water tablets (diuretics)
- Zafirlukast to treat asthma
- Illoprost to treat blood circulatory problems
- Cilostazol used in heart problems
- Metoclopramide used to ease vomiting and nausea
- Mifepristone used in termination of pregnancy
- Probenecid or Sulfinpyrazone used in the treatment of gout
- Sibutramine to help weight loss.
Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without prescription.
Aspirin 300 mg Tablets with Alcohol
Do not drink alcohol while you are taking Aspirin Tablets.
Pregnancy, breast-feeding and fertility
Do not take ASPIRIN 300 mg during pregnancy and breast-feeding as there are no data on the safety of the combination of both active substances. In addition, it should be taken into account that acetylsalicylic acid (aspirin):
May cause kidney and heart problems in your unborn baby when used from the
20th week of pregnancy.
- May harm your unborn child or cause problems at delivery when used during the last trimester of pregnancy.
- May affect the mother’s and baby’s tendency to bleed and cause labour to be later or longer than expected when used prior or during delivery.
If you are pregnant, or breast feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.
If you continue or start treatment with Aspirin during pregnancy per instruction of the physician, then use Aspirin as advised by your doctor and do not use a higher dose than is recommended.
Pregnancy - last trimester
Do not take Aspirin higher than 100 mg per day if you are in the last 3 months of pregnancy as it could harm your unborn child or cause problems at delivery. It can cause kidney and heart problems in your unborn baby. It may affect your and your baby’s tendency to bleed and cause labour to be later or longer than expected.
If you take Aspirin at low doses (up to and including 100 mg per day), you need strict obstetric monitoring as advised by your doctor.
Pregnancy – first and second trimester
You should not take Aspirin during the first 6 months of pregnancy unless absolutely necessary and advised by your doctor. If you need treatment during this period or while you are trying to get pregnant, the lowest dose for the shortest time possible should be used. If taken for more than a few days from 20 weeks of pregnancy onward, Aspirin can cause kidney problems in your unborn baby that may lead to low levels of amniotic fluid that surrounds the baby (oligohydramnios) or narrowing of a blood vessel (ductus arteriosus) in the heart of the baby. If you need treatment for longer than a few days, your doctor may recommend additional monitoring.
Aspirin 300 mg contains lactose
This medicinal product contains Lactose. If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicinal product.
3. HOW TO TAKE ASPIRIN 300 mg TABLETS
Always take this medicine exactly as described in this leaflet or as your doctor, pharmacist, or nurse have told you. Check with your doctor, pharmacist or nurse if you are not sure.
Adults including the elderly & children over 16years:
The usual dose is 2-3 tablets at intervals of 4-6 hours, with a maximum dose of 12 tablets.
Swallow the tablets with a glass of water.
Children 16 years and under:
Not recommended.
If you take more Aspirin 300 mg Tablets than you should
If you take more Aspirin Tablets than you should, contact your doctor or the nearest hospital emergency department immediately. Take the pack and remaining tablets with you. The following are symptoms of aspirin overdose: vomiting, dehydration, ringing in the ears, deafness, sweating, warm hands and feet, increased breathing or over breathing, vertigo (the sensation of spinning even when you are standing completely still).
If you forget to take Aspirin 300 mg Tablets
If you forget to take a dose, take it as soon as you remember unless it is almost time for your next dose. Do not take a double dose to make up for a forgotten tablet.
4. POSSIBLE SIDE EFFECTS
Like all medicines, this medicine can cause side effects, although not everybody gets them.
If any of the following happens, stop taking Aspirin Tablets and tell your doctor immediately or go to the nearest hospital emergency department:
- Rare allergic (hypersensitive) reactions such as difficulty of breathing or severe coughing, swelling of your face, throat or tongue, skin rash, itching or hives.
- Asthma attacks (condition that affects the airways of the lungs causing breathing difficulties)
- Bleeding from stomach and intestine with vomiting of blood & passage of black, tarry stools
- Prolonged bleeding time (especially in patients with Minot-Von Willebrand syndrome, a bleeding disorder) and bleeding disorders such as epistaxis (nose bleeds), appearance of blood in the urine.
Spontaneous bleeding into the skin usually appears as a rash known as purpura, bleeding into the skin, haematoma (collection of blood in tissue under the skin or in an internal organ due to injury to the tissue or organ, or to an abnormal bleeding tendency).
Other possible side effects:
- Indigestion, inflammation or irritation of the lining of the stomach, gastro-intestinal erosions, ulcers & holes in stomach and intestine
- Bleeding from stomach and intestine with vomiting of blood & passage of black, tarry stools
- Sudden and abrupt bleeding into the tissue of the brain.
Uncommon (may affect upto 1 in 100 people):
- Low blood sugar
- Fever
- Reduced platelet (thrombocyte) count
- Kidney failure
- Confusion
- Feeling lost or unsure of your location
- Coma
- Fits
If any of the side effects gets serious, or if you notice any side effects not listed in this leaflet, please tell your doctor or pharmacist.
Frequency not known:
- Acute myocardial ischemia (painful heart condition caused by lack of blood flow to the heart) with or without myocardial infarction (heart attack) occurring as part of an allergic reaction (Kounis syndrome).
Reporting of side effects
If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Yellow Card Scheme. Website: www.mhra.gov.uk/yellowcard or search for
MHRA Yellow Card in the Google Play or Apple App Store. By reporting side effects you can help provide more information on the safety of this medicine.
5. HOW TO STORE ASPIRIN 300mg TABLETS
Keep this medicine out of the sight and reach of children.
Do not store the tablets above 25°C. Store in the original pack.
Do not use this medicine after the expiry date which is stated on the pack. The expiry date refers to the last day of that month.
Do not throw away any medicines via wastewater or household waste. Ask your pharmacist how to throw away medicines you no longer use. These measures will help to protect the environment.
6. CONTENT OF THE PACK AND OTHERINFORMATION What Aspirin Tablets contain
The active substance is aspirin 300mg. The other ingredients are Lactose and Potato
Starch.
What Aspirin Tablets look like and contents of the pack
Aspirin Tablets are available as plain, white, uncoated tablets. They are available in packs of 16, 25, 32, 50, 100, 500 and 1000 tablets in container & 16, 30, 32 & 100 tablets in blister pack.
Not all pack sizes may be marketed.
Marketing Authorisation Holder and Manufacturer
Activase Pharmaceuticals Limited
11 Boumpoulinas, 3rd Floor
1060 Nicosia, Cyprus
PL 28444/0092
Manufacturer
DDSA Pharmaceuticals Limited
84 Pembroke Road
London
W8 6NX
UK
This leaflet was last revised in August 2026